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  1. Article

    Open Access

    Capsaicin consumption reduces brain amyloid-beta generation and attenuates Alzheimer’s disease-type pathology and cognitive deficits in APP/PS1 mice

    Alzheimer’s disease (AD) is the most common cause of age-related dementia and is currently incurable. The failures of current clinical trials and the establishment of modifiable risk factors have shifted the A...

    Jun Wang, Bin-Lu Sun, Yang **ang, Ding-Yuan Tian, Chi Zhu in Translational Psychiatry (2020)

  2. Article

    Open Access

    Disrupted intrinsic functional brain topology in patients with major depressive disorder

    Aberrant topological organization of whole-brain networks has been inconsistently reported in studies of patients with major depressive disorder (MDD), reflecting limited sample sizes. To address this issue, w...

    Hong Yang, **ao Chen, Zuo-Bing Chen, Le Li, Xue-Ying Li in Molecular Psychiatry (2021)

  3. Article

    Open Access

    Reduced nucleus accumbens functional connectivity in reward network and default mode network in patients with recurrent major depressive disorder

    The nucleus accumbens (NAc) is considered a hub of reward processing and a growing body of evidence has suggested its crucial role in the pathophysiology of major depressive disorder (MDD). However, inconsiste...

    Yu-Dan Ding, **ao Chen, Zuo-Bing Chen, Le Li, Xue-Ying Li in Translational Psychiatry (2022)