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  1. No Access

    Article

    PELO facilitates PLK1-induced the ubiquitination and degradation of Smad4 and promotes the progression of prostate cancer

    PLK1 and Smad4 are two important factors in prostate cancer initiation and progression. They have been reported to play the opposite role in Pten-deleted mice, one is an oncogene, the other is a tumor suppress...

    ** Gao, **g-Lan Hao, Qian-Wen **e, Gui-Qin Han, Bin-Bing Xu, Hang Hu… in Oncogene (2022)

  2. Article

    Open Access

    Two divergent haplotypes from a highly heterozygous lychee genome suggest independent domestication events for early and late-maturing cultivars

    Lychee is an exotic tropical fruit with a distinct flavor. The genome of cultivar ‘Feizixiao’ was assembled into 15 pseudochromosomes, totaling ~470 Mb. High heterozygosity (2.27%) resulted in two complete hap...

    Guibing Hu, Junting Feng, Xu **ang, Jiabao Wang, Jarkko Salojärvi… in Nature Genetics (2022)

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  3. Article

    Open Access

    GLIS2 promotes colorectal cancer through repressing enhancer activation

    Gene transcription is coordinately regulated by multiple transcription factors. However, a systematic approach is still lacking to identify co-regulators for transcription factors. Here, we performed ChIP-Seq ...

    Jie Yao, Pin-Ji Lei, Qing-Lan Li, Ji Chen, Shan-Bo Tang, Qiong **ao… in Oncogenesis (2020)

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  4. Article

    Corrigendum: Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54

    Nat. Genet. 42, 759–763 (2010); published online 22 August 2010; corrected after print 27 August 2014 In contrast to the version of this article initially published, the authors now find no evidence to support...

    Li-Dong Wang, Fu-You Zhou, Xue-Min Li, Liang-Dan Sun, **n Song, Yan **… in Nature Genetics (2014)

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  5. No Access

    Article

    Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations

    Dongxin Lin, Philip Taylor, Li-Dong Wang and colleagues have now pooled three genome-wide association analyses of esophageal squamous cell carcinoma, finding two new risk loci at genome-wide significance and a...

    Chen Wu, Zhaoming Wang, **n Song, **ao-Shan Feng, Christian C Abnet… in Nature Genetics (2014)

  6. No Access

    Article

    Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk

    Wei Zheng and colleagues report the results of a large-scale genome-wide association study of colorectal cancer in East Asians. They identify six new susceptibility loci, including variants near TCF7L2 and TGFB1.

    Ben Zhang, Wei-Hua Jia, Koichi Matsuda, Sun-Seog Kweon, Keitaro Matsuo… in Nature Genetics (2014)

  7. No Access

    Article

    Genome-wide association analyses in east Asians identify new susceptibility loci for colorectal cancer

    Wei Zheng and colleagues report genome-wide analyses in east Asians and identify three new loci associated with colorectal cancer risk.

    Wei-Hua Jia, Ben Zhang, Keitaro Matsuo, Aesun Shin, Yong-Bing **ang… in Nature Genetics (2013)

  8. No Access

    Article

    Genome-wide association study identifies two new susceptibility loci for atopic dermatitis in the Chinese Han population

    Xue-Jun Zhang, Zhi-Rong Yao and colleagues report a genome-wide association study for atopic dermatitis in the Chinese Han population. They identified two new susceptibility loci at 5q22 and 20q13.

    Liang-Dan Sun, Feng-Li **ao, Yang Li, Wen-Ming Zhou, Hua-Yang Tang… in Nature Genetics (2011)

  9. No Access

    Article

    Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies a susceptibility locus at PLCE1

    Li Dong Wang and colleagues report a genome wide association study for esophageal squamous cell carcinoma in the Chinese population. They identify two risk loci at PLCE1 and C20orf54.

    Li-Dong Wang, Fu-You Zhou, Xue-Min Li, Liang-Dan Sun, **n Song, Yan **… in Nature Genetics (2010)