1,644 Result(s)
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**g-Ying Zhang
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Article
Open AccessEasily misdiagnosed X-linked adrenoleukodystrophy
Addison’s disease and X-linked adrenoleukodystrophy (X-ALD) (Addison’s-only) are two diseases that need to be identified. Addison’s disease is easy to diagnose clinically when only skin and mucosal pigmentatio...
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Infrared-responsive shape memory self-healing and fluorescent damage-indication anti-corrosion coatings for aluminum alloys
Widely applied aluminum alloys in ship hulls, underwater vehicles, and marine machinery experience severe corrosion in harsh marine environments. For corrosion protection of aluminum alloys, the most convenien...
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Small-molecule caspase-1 inhibitor CZL80 terminates refractory status epilepticus via inhibition of glutamatergic transmission
Status epilepticus (SE), a serious and often life-threatening medical emergency, is characterized by abnormally prolonged seizures. It is not effectively managed by present first-line anti-seizure medications ...
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Oncoprotein LAMTOR5-mediated CHOP silence via DNA hypermethylation and miR-182/miR-769 in promotion of liver cancer growth
C/EBP homologous protein (CHOP) triggers the death of multiple cancers via endoplasmic reticulum (ER) stress. However, the function and regulatory mechanism of CHOP in liver cancer remain elusive. We have reporte...
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Circumventing brittleness of 3D-printed Al2O3 cellular ceramic structures via compositing with polyurea
Benefiting from excellent mechanical properties and low density, cellular ceramic structures (CCSs) are competitive candidates as structural components. However, inherent brittleness from strong chemical bonds...
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A non-invasive artificial intelligence model for identifying axillary pathological complete response to neoadjuvant chemotherapy in breast cancer: a secondary analysis to multicenter clinical trial
This study aims to develop a stacking model for accurately predicting axillary lymph node (ALN) response to neoadjuvant chemotherapy (NAC) using longitudinal MRI in breast cancer.
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Morphology-based genetic diversity analysis reveals introgressive hybridizations obscure species boundaries of three wild roses endemic to Taiwan Island
Interspecific hybridization in the genus Rosa (Rosaceae) is a common natural phenomenon. Hybrids often exhibit heterosis and new combinations of traits, which can provide raw materials for horticultural breeding....
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Role of inclination angle on columnar-to-equiaxed transition in the eutectic Al-5Mg-2Si alloy fabricated by laser powder bed fusion
In this study, the effect of inclination angles relative to the building direction in the additively manufactured eutectic Al-5Mg-2Si alloy was investigated through the laser powder bed fusion (LPBF). The micr...
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Article
Association Between a Failed Prominence Eruption and the Drainage of Mass from Another Prominence
Sympathetic eruptions of solar prominences have been studied for decades, however, it is usually difficult to identify their causal links. Here, we present two failed prominence eruptions on 26 October 2022 an...
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Glial growth factor 2 treatment alleviates ischemia and reperfusion-damaged integrity of the blood-brain barrier through decreasing Mfsd2a/caveolin-1-mediated transcellular and Pdlim5/YAP/TAZ-mediated paracellular permeability
The impairment of blood-brain barrier (BBB) integrity is the pathological basis of hemorrhage transformation and vasogenic edema following thrombolysis and endovascular therapy. There is no approved drug in th...
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Open AccessAugmented microglial endoplasmic reticulum-mitochondria contacts mediate depression-like behavior in mice induced by chronic social defeat stress
Extracellular ATP (eATP) signaling through the P2X7 receptor pathway is widely believed to trigger NLRP3 inflammasome assembly in microglia, potentially contributing to depression. However, the cellular stress...
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A global survey on the use of the international classification of diseases codes for metabolic dysfunction-associated fatty liver disease
With the implementation of the 11th edition of the International Classification of Diseases (ICD-11) and the publication of the metabolic dysfunction-associated fatty liver disease (MAFLD) nomenclature in 2020...
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Open AccessThe role of minimal residual disease and serum free light chain ratio in the management of multiple myeloma
Multiple myeloma (MM) denotes a cancerous growth characterized by abnormal proliferation of plasma cells. Growing evidence suggests that the complexity in addressing MM lies in the presence of minimal residual...
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HBXIP induces PARP1 via WTAP-mediated m6A modification and CEBPA-activated transcription in cisplatin resistance to hepatoma
Poly (ADP-ribose) polymerase 1 (PARP1) is a DNA-binding protein that is involved in various biological functions, including DNA damage repair and transcription regulation. It plays a crucial role in cisplatin ...
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Open AccessA comprehensive analysis of GAS2 family members identifies that GAS2L1 is a novel biomarker and promotes the proliferation of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a common primary liver cancer with a high incidence and mortality. Members of the growth-arresting-specific 2 (GAS2) family are involved in various biological processes in hum...
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Open AccessPE/PPE mutations in the transmission of Mycobacterium tuberculosis in China revealed by whole genome sequencing
This study aims to examine the impact of PE/PPE gene mutations on the transmission of Mycobacterium tuberculosis (M. tuberculosis) in China.
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Open AccessRandom forest differentiation of Escherichia coli in elderly sepsis using biomarkers and infectious sites
This study addresses the challenge of accurately diagnosing sepsis subtypes in elderly patients, particularly distinguishing between Escherichia coli (E. coli) and non-E. coli infections. Utilizing machine learni...
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Soil moisture drives the shift from selection to complementarity effect in the rainfed maize/faba bean intercrop** system
Selection effect (SE) and complementarity effect (CE) are often considered as two key indicators to mediate the positive diversity-productivity relationship in the maize-legume intercrop** system, as intercr...
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Effect of TiO2 addition on microstructures and properties of MgO–CaO refractory aggregates
MgO–CaO (40 wt.% CaO) refractory aggregates were prepared using the calcined dolomite and light-burned magnesia fine powder as raw materials and TiO2 as additive. The effect of TiO2 on their phase composition, mi...
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Discovery of a selective TRF2 inhibitor FKB04 induced telomere shortening and senescence in liver cancer cells
Telomere repeat binding factor 2 (TRF2), a critical element of the shelterin complex, plays a vital role in the maintenance of genome integrity. TRF2 overexpression is found in a wide range of malignant cancer...
