97 Result(s)

Article

Aerosolised surfactant generated by a novel noninvasive apparatus reduced acute lung injury in rats

Exogenous surfactant has been explored as a potential therapy for acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). In the present study, a nebuliser driven by oxygen lines found in the h...

Yu Sun, Rui Yang, Ji-gen Zhong, Feng Fang, **-** Jiang, Ming-yao Liu… in Critical Care (2009)

Article

The interaction of HAb18G/CD147 with integrin α6β1 and its implications for the invasion potential of human hepatoma cells

HAb18G/CD147 plays pivotal roles in invasion by hepatoma cells, but the underlying mechanism remains unclear. Our previous study demonstrated that overexpression of HAb18G/CD147 promotes invasion by interactin...

**g-yao Dai, Ke-feng Dou, Cong-hua Wang, Pu Zhao, Wayne Bond Lau, Ling Tao… in BMC Cancer (2009)

Article

Isolation and characterization of exopolysaccharide with immunomodulatory activity from fermentation broth of Morchella conica

Mushroom polysaccharides have traditionally been used for the prevention and treatment of a multitude of disorders like infectious illnesses, cancers and various autoimmune diseases. In vitro and in vivo studies ...

Chao-an Su, **ao-yan Xu, De-yun Liu, Ming Wu… in DARU Journal of Pharmaceutical Sciences (2013)

Article

A reporter gene system for screening inhibitors of Wnt signaling pathway

Abnormal activation of canonical Wnt signaling has been associated with various types of cancer. Inhibitory reagents targeting the Wnt signaling have great potential to inhibit the growth of relevant tumors. H...

**ng-Yao Li, Yuan-Yuan Wang, Chun-Mao Yuan… in Natural Products and Bioprospecting (2013)

Article

PJS, a novel isocoumarin with hexahydropyrimidine ring from Bacillus subtilis PJS

Shao-Wei Liu, **g **, Chuan Chen, Jia-Meng Liu, **g-Yan Li… in The Journal of Antibiotics (2013)

Article

Over-expression of BCAT1, a c-Myc target gene, induces cell proliferation, migration and invasion in nasopharyngeal carcinoma

Nasopharyngeal carcinoma (NPC) is a common malignant tumor in southern China and Southeast Asia, but its molecular mechanisms of pathogenesis are poorly understood. Our previous work has demonstrated that BCAT1 m...

Wen Zhou, **angling Feng, Cai** Ren, **ngjun Jiang, Weidong Liu… in Molecular Cancer (2013)

Article

High throughput sequencing of two celery varieties small RNAs identifies microRNAs involved in temperature stress response

MicroRNAs (miRNAs) are small, non-coding RNAs of 20 to 24 nucleotides that regulate gene expression and responses to biotic and abiotic stress. Till now, no reports have previously been published concerning mi...

Meng-Yao Li, Feng Wang, Zhi-Sheng Xu, Qian Jiang, **g Ma, Guo-Fei Tan… in BMC Genomics (2014)

Article

Optical properties of epitaxial BiFeO₃ thin film grown on SrRuO₃-buffered SrTiO₃ substrate

The BiFeO₃ (BFO) thin film was deposited by pulsed-laser deposition on SrRuO₃ (SRO)-buffered (111) SrTiO₃ (STO) substrate. X-ray diffraction pattern reveals a well-grown epitaxial BFO thin film. Atomic force micr...

Ji-** Xu, Rong-Jun Zhang, Zhi-Hui Chen, Zi-Yi Wang… in Nanoscale Research Letters (2014)

Article

Overexpression of fibrinogen-like protein 2 induces epithelial-to-mesenchymal transition and promotes tumor progression in colorectal carcinoma

The main cause of death in colorectal carcinoma (CRC) patients is tumor metastasis; however, the underlying molecular mechanisms are largely unknown. In the present study, a novel metastasis-related gene, fi...

Wen-Zheng Qin, Quan-Lin Li, Wei-Feng Chen, Mei-Dong Xu, Yi-Qun Zhang… in Medical Oncology (2014)

Article

Effect of controlled rolling/controlled cooling parameters on microstructure and mechanical properties of the novel pipeline steel

The study of controlled rolling/controlled cooling process parameters which affect the microstructure and mechanical properties of a novel pipeline steel have been optimized by the orthogonal experiment with f...

Min Jiang, Li-Na Chen, ** He, Guang-Yao Chen, Chong-He Li… in Advances in Manufacturing (2014)

Article

The anti-fibrotic effects of mesenchymal stem cells on irradiated lungs via stimulating endogenous secretion of HGF and PGE2

Radiation-induced pulmonary fibrosis is a common disease and has a poor prognosis owing to the progressive breakdown of gas exchange regions in the lung. Recently, a novel strategy of administering mesenchymal...

Li-Hua Dong, Yi-Yao Jiang, Yong-Jun Liu, Shuang Cui, Cheng-Cheng **a… in Scientific Reports (2015)

Article

Epigenetics of Notch1 regulation in pulmonary microvascular rarefaction following extrauterine growth restriction

Extrauterine growth restriction (EUGR) plays an important role in the developmental origin of adult cardiovascular diseases. In an EUGR rat model, we reported an elevated pulmonary arterial pressure in adults ...

Li-Li Tang, Li-Yan Zhang, Lin-Jiang Lao, Qiong-Yao Hu, Wei-Zhong Gu… in Respiratory Research (2015)

Article

High-throughput sequencing of small RNAs and anatomical characteristics associated with leaf development in celery

MicroRNAs (miRNAs) exhibit diverse and important roles in plant growth, development and stress responses and regulate gene expression at the post-transcriptional level. Knowledge about the diversity of miRNAs ...

**ao-Ling Jia, Meng-Yao Li, Qian Jiang, Zhi-Sheng Xu, Feng Wang… in Scientific Reports (2015)

Article

Genetic diversity and evolutionary dynamics of Ebola virus in Sierra Leone

The genome sequences of 175 Ebola virus from five districts in Sierra Leone, collected during September–November 2014, show that the rate of virus evolution seems to be similar to that observed during previous...

Yi-Gang Tong, Wei-Feng Shi, Di Liu, Jun Qian, Long Liang, **ao-Chen Bo, Jun Liu… in Nature (2015)

Article

Metformin can block precancerous progression to invasive tumors of bladder through inhibiting STAT3-mediated signaling pathways

Metformin is the first line of oral antidiabetic drug in the biguanide class for treatment of type 2 diabetes. Increasing evidence has suggested that it is a potential anti-tumor drug. However, the mechanisms ...

Qi Pan, Guo-Liang Yang, Jiang-Hua Yang… in Journal of Experimental & Clinical Cancer … (2015)

Article

Erratum: Genetic diversity and evolutionary dynamics of Ebola virus in Sierra Leone

Nature 524, 93–96 (2015); doi:10.1038/nature14490 This Letter should have contained an associated Creative Commons statement in the Author Information section. In addition, the Fig. 3c legend should have state...

Yi-Gang Tong, Wei-Feng Shi, Di Liu, Jun Qian, Long Liang, **ao-Chen Bo, Jun Liu… in Nature (2015)

Article

Effects of two different anesthesia-analgesia methods on incidence of postoperative delirium in elderly patients undergoing major thoracic and abdominal surgery: study rationale and protocol for a multicenter randomized controlled trial

Delirium is a common complication in elderly patients after surgery and associated with increased morbidity and mortality. Studies suggest that deep anesthesia and intense pain are important precipitating fact...

Ya-Wei Li, Hui-Juan Li, Huai-** Li, Yi Feng, Yao Yu, **ang-Yang Guo… in BMC Anesthesiology (2015)

Article

Low c-Met expression levels are prognostic for and predict the benefits of temozolomide chemotherapy in malignant gliomas

Aberrant c-Met has been implicated in the development of many cancers. The objective of this study was to identify an unfavorable prognostic marker that might guide decisions regarding clinical treatment strat...

Ming-Yang Li, Pei Yang, Yan-Wei Liu, Chuan-Bao Zhang, Kuan-Yu Wang… in Scientific Reports (2016)

Article

XXIV World Allergy Congress 2015

A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts

Heung-Man Lee, Il-Ho Park, Jae-Min Shin… in World Allergy Organization Journal (2016)

Article

Mensenchymal stem cells can delay radiation-induced crypt death: impact on intestinal CD44⁺ fragments

Intestinal stem cells are primitive cells found within the intestinal epithelium that play a central role in maintaining epithelial homeostasis through self-renewal and commitment into functional epithelial ce...

Peng-Yu Chang, **ng **, Yi-Yao Jiang, Li-**an Wang… in Cell and Tissue Research (2016)