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Article
Genomic study of PIFs in cotton and functional analysis of GhPIF4 in promoting cotton flowering
Cotton is the most important commercial crop in the production of fiber for the textile industry worldwide, and flowering time is an important agronomic trait for cotton production. Phytochrome interacting fac...
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Article
Reasonable suppression of polysulfides/polyselenides shuttle based on MXene in Na-SeS2 batteries
Metal-sulfur/selenium batteries have become the focus of new-generation energy storage systems due to the advantages of low-cost and high energy density. However, it still suffers from the notorious shuttle of...
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Article
Open AccessMeplazumab in hospitalized adults with severe COVID-19 (DEFLECT): a multicenter, seamless phase 2/3, randomized, third-party double-blind clinical trial
Meplazumab, a humanized CD147 antibody, has shown favourable safety and efficacy in our previous clinical studies. In DEFLECT (NCT04586153), 167 patients with severe COVID-19 were enroled and randomized to rec...
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Article
Near-infrared carbon nanodots for effective identification and inactivation of Gram-positive bacteria
An unacceptable increase in antibacterial resistance has arisen due to the abuse of multiple classes of broad-spectrum antibiotics. Therefore, it is significant to develop new antibacterial agents, especially ...
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Article
Oncogenic potential of BEST4 in colorectal cancer via activation of PI3K/Akt signaling
BEST4 is a member of the bestrophin protein family that plays a critical role in human intestinal epithelial cells. However, its role and mechanism in colorectal cancer (CRC) remain largely elusive. Here, we i...
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Article
Open AccessIdentification of NHXs in Gossypium species and the positive role of GhNHX1 in salt tolerance
Plant Na+/H+ antiporters (NHXs) are membrane-localized proteins that maintain cellular Na+/K+ and pH homeostasis. Considerable evidence highlighted the critical roles of NHX family in plant development and salt r...
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Article
Open AccessLnc SMAD5-AS1 as ceRNA inhibit proliferation of diffuse large B cell lymphoma via Wnt/β-catenin pathway by sponging miR-135b-5p to elevate expression of APC
Diffuse large B cell lymphoma (DLBCL) is a common and fatal hematological malignancy. Long noncoding RNAs (lncRNAs) have emerged as crucial biomarkers and regulators in many cancers. Novel lncRNA biomarker in ...
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Article
Silencing of GbANS reduces cotton resistance to Verticillium dahliae through decreased ROS scavenging during the pathogen invasion process
Anthocyanins are secondary metabolites that play important roles in plant adaption to adverse environments. The anthocyanin biosynthetic pathway is conserved in high plants. Previous studies revealed the signi...
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Article
Heterogeneous expression of the cotton R2R3-MYB transcription factor GbMYB60 increases salt sensitivity in transgenic Arabidopsis
MYB proteins form one of the largest transcription factor families in plants. Growing evidence has suggested that MYB has important roles in the regulation of plant growth and development, as well as responses...
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Article
Open AccessCalcium-dependent protein kinases in cotton: insights into early plant responses to salt stress
Soil salinization is one of the major environmental constraints to plant growth and agricultural production worldwide. Signaling components involving calcium (Ca2+) and the downstream calcium-dependent protein ki...
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Article
Open AccessGenomes of the rice pest brown planthopper and its endosymbionts reveal complex complementary contributions for host adaptation
The brown planthopper, Nilaparvata lugens, the most destructive pest of rice, is a typical monophagous herbivore that feeds exclusively on rice sap, which migrates over long distances. Outbreaks of it have re-occ...
