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  1. Article

    Open Access

    Changing surface ocean circulation caused the local demise of echinoid Scaphechinus mirabilis in Taiwan during the Pleistocene–Holocene transition

    Abundant fossil specimens of Scaphechinus mirabilis, now occurring mostly in temperate waters, have been found in the Toukoshan Formation (Pleistocene) in Miaoli County, Taiwan. Environmental changes leading to i...

    Sze Ling Ho, Jia-Kang Wang, Yu-Jou Lin, Ching-Ren Lin, Chen-Wei Lee in Scientific Reports (2022)

  2. Article

    Open Access

    Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation

    Human ribonuclease 1 (hRNase 1) is critical to extracellular RNA clearance and innate immunity to achieve homeostasis and host defense; however, whether it plays a role in cancer remains elusive. Here, we demo...

    Heng-Huan Lee, Ying-Nai Wang, Wen-Hao Yang, Weiya **a, Yongkun Wei in Nature Communications (2021)

  3. Article

    Open Access

    A Smartphone-based Diffusometric Immunoassay for Detecting C-Reactive Protein

    In this study, we developed a portable smartphone-based diffusometry for analyzing the C-reactive protein (CRP) concentration. An optimized fluorescence microscopic add-on system for a smartphone was used to i...

    Chih-Shen Chuang, Chih-Zong Deng, Yi-Fan Fang, Hong-Ren Jiang in Scientific Reports (2019)

  4. Article

    Open Access

    Submarine Groundwater Discharge helps making nearshore waters heterotrophic

    Submarine groundwater discharge (SGD) is the submarine seepage of all fluids from coastal sediments into the overlying coastal seas. It has been well documented that the SGD may contribute a great deal of allo...

    Shu-Lun Wang, Chen-Tung Arthur Chen, Ting-Hsuan Huang in Scientific Reports (2018)

  5. Article

    Open Access

    Risk of Band Keratopathy in Patients with End-Stage Renal Disease

    This study is a retrospective, nationwide, matched cohort study to investigate the risk of band keratopathy following end-stage renal disease (ESRD). The study cohort included 94,039 ESRD on-dialysis patients ...

    Shih-Feng Weng, Ren-Long Jan, Chun Chang, Jhi-Joung Wang, Shih-Bin Su in Scientific Reports (2016)