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  1. No Access

    Article

    Retreatment Efficacy and Renal Safety of Tenofovir Alafenamide, Entecavir, and Tenofovir Disoproxil Fumarate After Entecavir or Tenofovir Cessation

    We aimed to compare the one-year retreatment efficacy and renal safety of entecavir, tenofovir disoproxil fumarate (TDF), and tenofovir alafenamide (TAF) after HBV relapse in patients who discontinued entecavi...

    Shao-Ming Chiu, Kuo-Chin Chang, Tsung-Hui Hu in Digestive Diseases and Sciences (2023)

  2. No Access

    Article

    Validation of an alpha-fetoprotein model to predict recurrence after liver resection for hepatocellular carcinoma

    To validate a previously reported alpha-fetoprotein (AFP) model (including three variables: preoperative image-diagnosed tumor number and size and AFP level) for the prediction of recurrence in hepatocellular ...

    Wei-Feng Li, Yi-Hao Yen, Yueh-Wei Liu, Chih-Chi Wang, Chee-Chien Yong in Updates in Surgery (2022)

  3. No Access

    Article

    Predictors of Virological Suppression After Clinical Relapse in Patients Who Discontinued Entecavir or Tenofovir

    The predictors of persistent virological suppression after clinical relapse remain unclear.

    Hsin-Wei Fang, Yi-Hao Yen, Chao-Hung Hung in Digestive Diseases and Sciences (2022)

  4. No Access

    Article

    The characteristics of patients with macrovascular invasion in hepatocellular carcinoma: when East meets West

    To evaluate the prevalence and extension of macrovascular invasion (MaVI) in a large cohort of hepatocellular carcinoma (HCC) patients and analyze the association between MaVI and overall survival (OS).

    Yi-Hao Yen, Wei-Feng Li, Kwong-Ming Kee, Chih-Chi Wang in Langenbeck's Archives of Surgery (2022)

  5. No Access

    Article

    Long-term outcome of liver complications in patients with chronic HBV/HCV co-infection after antiviral therapy: a real-world nationwide study on Taiwanese Chronic Hepatitis C Cohort (T-COACH)

    The long-term outcome of hepatitis B virus (HBV) infection among patients dually infected with HBV and hepatitis C virus (HCV) remains unclear. We aimed to investigate the long-term liver outcomes of HBV/HCV-c...

    Ming-Lun Yeh, Chao-Hung Hung, Kuo-Chih Tseng, Hsueh-Chou Lai in Hepatology International (2021)

  6. No Access

    Article

    Liver resection in elderly patients with hepatocellular carcinoma: age does matter

    Increasing proportions of elderly patients with hepatocellular carcinoma (HCC) requiring oncological treatment have been noted. We aim to evaluate the impact of elderly age on outcomes of liver resection (LR) ...

    Yueh-Wei Liu, Chee-Chien Yong, Chih-Che Lin, Chih-Chi Wang in Updates in Surgery (2021)

  7. No Access

    Article

    A novel evidence of serial changes of bone mineral density in chronic hepatitis B patients treated with entecavir

    Tenofovir disoproxil fumarate (TDF) and Entecavir (ETV) are commonly used for patients with chronic hepatitis B (CHB), and renal or bone toxicity are possible concerns. This study is to evaluate the renal and ...

    Pao-Yuan Huang, Sherry Yueh-Hsia Chiu, Kuo-Chin Chang in Hepatology International (2021)

  8. No Access

    Article

    Combining end-of-treatment HBsAg and baseline hepatitis B core-related antigen reduce HBV relapse rate after tenofovir cessation

    The study investigated the role of hepatitis B core-related antigen (HBcrAg) in hepatitis B virus (HBV) relapse after stop** tenofovir disoproxil fumarate (TDF) in HBeAg-negative patients.

    Yuan-Hung Kuo, **g-Houng Wang, Chao-Hung Hung, Sheng-Nan Lu in Hepatology International (2021)

  9. No Access

    Article

    Six months as a cutoff time point to define early recurrence after liver resection of hepatocellular carcinoma based on post-recurrence survival

    To determine the optimal cutoff time point of early versus late recurrence relative to post-recurrence survival (PRS) among patients who underwent liver resection (LR) for hepatocellular carcinoma (HCC) in a h...

    Yueh-Wei Liu, Chee-Chien Yong, Chih-Che Lin, Chih-Chi Wang in Updates in Surgery (2021)

  10. No Access

    Article

    Incidence and predictors of hepatocellular carcinoma beyond year 5 of entecavir therapy in chronic hepatitis B patients

    The study compared the incidence and predictors of hepatocellular carcinoma (HCC) within and beyond year 5 of entecavir (ETV) therapy.

    Fai-Meng Sou, Tsung-Hui Hu, Chao-Hung Hung, Hsueh-Chou Lai in Hepatology International (2020)

  11. No Access

    Article

    Comparison of HBsAg changes between HBeAg-negative patients who discontinued or maintained entecavir therapy

    The study compared the hepatitis B surface antigen (HBsAg) changes between hepatitis B e antigen (HBeAg)-negative non-cirrhotic chronic hepatitis B patients who discontinued or maintained entecavir therapy.

    Chien-Hung Chen, Tsung-Hui Hu, **g-Houng Wang, Hsueh-Chou Lai in Hepatology International (2020)

  12. No Access

    Article

    Usefulness of Controlled Attenuation Parameter in Detecting and Monitoring Hepatic Steatosis with MRI-PDFF as Reference

    Controlled attenuation parameter (CAP) has been developed to estimate the extent of hepatic steatosis.

    **g-Houng Wang, Hsin-You Ou, Yi-Hao Yen in Digestive Diseases and Sciences (2020)

  13. No Access

    Article

    The influence of direct-acting antivirals in hepatitis C virus related hepatocellular carcinoma after curative treatment

    This study was done to elucidate the influence of direct-acting antiviral (DAA) agents on the recurrence of hepatocellular carcinoma (HCC) in patients with hepatitis C virus (HCV)-related HCC (HCV-HCC) after c...

    Yuan-Hung Kuo, **g-Houng Wang, Kuo-Chin Chang, Chao-Hung Hung in Investigational New Drugs (2020)

  14. Article

    Open Access

    Plasma fatty acid-binding protein 4 (FABP4) level is associated with abnormal QTc interval in patients with stable angina and chronic kidney disease

    Fatty acid-binding protein 4 (FABP4) (also known as adipocyte FABP or adipocyte P2) is expressed in adipocytes, macrophages, and capillary endothelial cells. Previous studies have shown associations among plas...

    Chao-** Wang, Chia-Chang Hsu, Wei-Chin Hung, Teng-Hung Yu in BMC Cardiovascular Disorders (2019)

  15. No Access

    Article

    The outcome of sorafenib monotherapy on hepatocellular carcinoma with portal vein tumor thrombosis

    Sorafenib is not recommended for advanced hepatocellular carcinoma (HCC) patients with Vp4 (portal invasion at the main trunk) by the Japan Society of Hepatology (JSH) due to a risk of hepatic failure. This st...

    Yuan-Hung Kuo, I-Pei Wu, **g-Houng Wang, Chao-Hung Hung in Investigational New Drugs (2018)

  16. Article

    Open Access

    Peripheral blood toll-like receptor 4 correlates with rapid virological response to pegylated-interferon and ribavirin therapy in hepatitis C genotype 1 patients

    Toll-like receptors (TLRs) are effectors of the innate immune system that are able to recognize hepatitis C virus (HCV) and give rise to an immune response. Failure of interferon (IFN)-α-based treatment is rel...

    Chuan-Mo Lee, Tsung-Hui Hu, Sheng-Nan Lu, **g-Houng Wang in BMC Gastroenterology (2016)

  17. No Access

    Article

    Clinical Impact of Gadoxetic Acid-Enhanced Magnetic Resonance Imaging on Hepatoma Management: A Prospective Study

    For patients with hepatocellular carcinoma (HCC), gadoxetic acid-enhanced magnetic resonance imaging (EOB-MRI) improved the diagnosis, migrated Barcelona Clinic Liver Cancer (BCLC) stage, and changed therapeu...

    **g-Houng Wang, Tai-Yi Chen, Hsin-You Ou, Chih-Chi Wang in Digestive Diseases and Sciences (2016)

  18. No Access

    Article

    High Risk of Hepatitis B Virus Reactivation in Nucleos(t)ide Analogue-Induced Hepatitis B e Antigen Seroconverters Older Than 40 Years

    A recent study showed that chronic hepatitis B virus (HBV) carriers with nucleos(t)ide analogue (NA)-induced hepatitis B antigen (HBeAg) seroconversion occurring before the age of 30 years have a higher risk o...

    Li-Fu Kuo, Chuan-Mo Lee, Chao-Hung Hung, **g-Houng Wang in Digestive Diseases and Sciences (2014)

  19. No Access

    Article

    Patients with interferon-induced HBeAg seroconversion have a higher risk of HBV reactivation and HBeAg seroreversion

    It remains unclear whether chronic hepatitis B patients who undergo interferon (IFN)-induced hepatitis B e antigen (HBeAg) seroconversion have a higher risk of hepatitis B virus (HBV) reactivation and HBeAg se...

    Chien-Hung Chen, Sheng-Nan Lu, Chuan-Mo Lee, Chao-Hung Hung in Hepatology International (2014)

  20. No Access

    Article

    Ultrasonographic Quantification of Hepatic–Renal Echogenicity Difference in Hepatic Steatosis Diagnosis

    Ultrasound (US) is recommended for hepatic steatosis screening. The purpose of this study was to determine the usefulness of US hepatic-renal echo-intensity (HR) difference in the quantitative assessment of he...

    **g-Houng Wang, Chao-Hung Hung, Fang-Ying Kuo in Digestive Diseases and Sciences (2013)

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