15 Result(s)
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Article
Open AccessTransplantation of gut microbiota derived from patients with schizophrenia induces schizophrenia-like behaviors and dysregulated brain transcript response in mice
Schizophrenia (SCZ), as a neurodevelopmental disorder and devastating disease, affects approximately 1% of the world population. Although numerous studies have attempted to elucidate the causes of SCZ occurren...
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Open AccessNAD+ exhaustion by CD38 upregulation contributes to blood pressure elevation and vascular damage in hypertension
Hypertension is characterized by endothelial dysfunction and arterial stiffness, which contribute to the pathogenesis of atherosclerotic cardiovascular diseases. Nicotinamide adenine dinucleotide (NAD+) is an ind...
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Article
Cardiovascular physiological effects of balneotherapy: focused on seasonal differences
Hot water bathing has been demonstrated to be an effective way to improve people’s cardiovascular health in many studies. This study focused on seasonal physiological changes to provide suggestions on bathing ...
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Open AccessReal-world study of the effectiveness of BBIBP-CorV (Sinopharm) COVID-19 vaccine in the Kingdom of Morocco
The Kingdom of Morocco approved BBIBP-CorV (Sinopharm) COVID-19 vaccine for emergency use on 22 January 2021 in a two-dose, three-to-four-week interval schedule. We conducted a retrospective cohort study to de...
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Hesperadin suppresses pancreatic cancer through ATF4/GADD45A axis at nanomolar concentrations
Pancreatic cancer (PC) is a fatal disease with poor survival and limited therapeutic strategies. In this study, we identified Hesperadin as a potent anti-cancer compound against PC, from a high-throughput scre...
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Open AccessAn electrographic AV optimization for the maximum integrative atrioventricular and ventricular resynchronization in CRT
Atrioventricular (AV) delay could affect AV and ventricular synchrony in cardiac resynchronization therapy (CRT). Strategies to optimize AV delay according to optimal AV synchrony (AVopt-AV) or ventricular synchr...
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Article
PGC-1α gene transfer restores adhesion and reendothelialization of endothelial progenitor cells from patients with hypertension
Endothelial progenitor cells (EPCs) play an important role in endothelial vascular development and endothelial repair. The upregulation of functional gene expression in EPCs may contribute to the maintenance o...
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Open AccessEsophagectomy versus definitive chemoradiotherapy for patients with clinical stage N0 and pathological stage T1b esophageal squamous cell carcinoma after endoscopic submucosal dissection: study protocol for a multicenter randomized controlled trial (Ad-ESD Trial)
Esophagectomy is still advised as an additional treatment for pathological T1b (pT1b) esophageal squamous cell carcinoma (ESCC) following attempted endoscopic resection (ER). ER followed with definitive chemor...
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Open AccessCorrection to: Systemic microvascular rarefaction is correlated with dysfunction of late endothelial progenitor cells in mild hypertension: a substudy of EXCAVATION-CHN1
Upon publication of the original article [1], it was noticed that Jun Tao’s affiliation information is not complete. The full affiliation information for Jun Tao can be found below and in the complete affiliat...
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Chronic remote ischemic preconditioning-induced increase of circulating hSDF-1α level and its relation with reduction of blood pressure and protection endothelial function in hypertension
Although previous data showed that remote ischemic preconditioning (RIPC) has beneficial effect on blood pressure (BP) reduction, the efficacy of RIPC-induced decline in BP and the favorable humoral factors in...
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Article
Open AccessSystemic microvascular rarefaction is correlated with dysfunction of late endothelial progenitor cells in mild hypertension: a substudy of EXCAVATION-CHN1
Hypertension often presents with microvascular rarefaction (MVR), which is closely associated with impaired angiogenesis. Early detection of MVR is essential for systemic assessment in patient with hypertensio...
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Article
Health effects of seasonal variation in cardiovascular hemodynamics among workers in forest environments
Seasonal variation in cardiovascular functions (CVFs) associated with climatic changes is an important emerging public health issue. The objectives of this study were to demonstrate seasonal variation in CVFs ...
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The Intersection of Gender and Sexuality: Sexism Shapes Men’s Same-Sex Sexuality in Terms of Self-Label Identification and Partner Choice in China
We examined how sexism related to gay and bisexual men’s preferences for same-sex top (dominant) or bottom (submissive) sexuality in China. Specifically, we determined the impacts of sexism on sexual self-labe...
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Open AccessDifferential effects of the changes of LDL cholesterol and systolic blood pressure on the risk of carotid artery atherosclerosis
The effects of baseline and changes in blood pressure and low density lipoprotein (LDL) cholesterol on the carotid intima media thickness (IMT) have not been well documented.
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Open AccessHeritability and major gene effects on left ventricular mass in the Chinese population: a family study
Genetic components controlling for echocardiographically determined left ventricular (LV) mass are still unclear in the Chinese population.
