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Article
Open AccessAntiferromagnetic magnonic charge current generation via ultrafast optical excitation
Néel spin-orbit torque allows a charge current pulse to efficiently manipulate the Néel vector in antiferromagnets, which offers a unique opportunity for ultrahigh density information storage with high speed. ...
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Article
Open AccessThe status of binocular visual functions among Taiwan high-tech industry engineers and its correlation with computer vision symptom
To analyze the status of binocular visual functions, the relationship between binocular visual function and computer vision-related symptoms in the high-tech industry group. The study sample was comprised of 3...
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Open AccessStructural mechanism of R2D2 and Loqs-PD synergistic modulation on DmDcr-2 oligomers
Small interference RNAs are the key components of RNA interference, a conserved RNA silencing or viral defense mechanism in many eukaryotes. In Drosophila melanogaster, Dicer-2 (DmDcr-2)-mediated RNAi pathway pla...
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Article
Open AccessEnhancing the reliability of particulate matter sensing by multivariate Tobit model using weather and air quality data
Low-cost particulate matter (PM) sensors have been widely used following recent sensor-technology advancements; however, inherent limitations of low-cost monitors (LCMs), which operate based on light scatterin...
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Article
Open AccessPlasmodium falciparum has evolved multiple mechanisms to hijack human immunoglobulin M
Plasmodium falciparum causes the most severe malaria in humans. Immunoglobulin M (IgM) serves as the first line of humoral defense against infection and potently activates the complement pathway to facilitate P. ...
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Article
Immunoglobulin M perception by FcμR
Immunoglobulin M (IgM) is the first antibody to emerge during embryonic development and the humoral immune response1. IgM can exist in several distinct forms, including monomeric, membrane-bound IgM within the B ...
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Article
Open AccessAschoff’s rule on circadian rhythms orchestrated by blue light sensor CRY2 and clock component PRR9
Circadian pace is modulated by light intensity, known as the Aschoff’s rule, with largely unrevealed mechanisms. Here we report that photoreceptor CRY2 mediates blue light input to the circadian clock by direc...
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Article
Open AccessImpact of mirabegron versus solifenacin on autonomic function and arterial stiffness in female overactive bladder syndrome: a randomized controlled trial
The study aims to elucidate the impact of mirabegron versus solifenacin on autonomic function and peripheral arterial conditions in women with overactive bladder syndrome (OAB). All consecutive women with OAB ...
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Article
Open AccessStructural insights into dsRNA processing by Drosophila Dicer-2–Loqs-PD
Small interfering RNAs (siRNAs) are the key components for RNA interference (RNAi), a conserved RNA-silencing mechanism in many eukaryotes1,2. In Drosophila, an RNase III enzyme Dicer-2 (Dcr-2), aided by its cofa...
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Article
Open AccessCrystal structures and insights into precursor tRNA 5’-end processing by prokaryotic minimal protein-only RNase P
Besides the canonical RNA-based RNase P, pre-tRNA 5’-end processing can also be catalyzed by protein-only RNase P (PRORP). To date, various PRORPs have been discovered, but the basis underlying substrate bindi...
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Article
Open AccessIdentification of transcriptional regulatory network associated with response of host epithelial cells to SARS-CoV-2
Identification of transcriptional regulatory mechanisms and signaling networks involved in the response of host cells to infection by SARS-CoV-2 is a powerful approach that provides a systems biology view of g...
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Article
Open AccessThe ability of physical activity in reducing mortality risks and cardiovascular loading and in extending life expectancy in patients with COPD
For chronic obstructive pulmonary disease (COPD), the role of physical activity in reducing COPD mortality and heart loading and in extending life expectancy remains unclear. Participants in comprehensive medi...
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Article
Open AccessHygroscopic properties of particulate matter and effects of their interactions with weather on visibility
The hygroscopic property of particulate matter (PM) influencing light scattering and absorption is vital for determining visibility and accurate sensing of PM using a low-cost sensor. In this study, we examine...
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Article
Open AccessA rotationally focused flow (RFF) microfluidic biosensor by density difference for early-stage detectable diagnosis
Label-free optical biosensors have received tremendous attention in point-of-care testing, especially in the emerging pandemic, COVID-19, since they advance toward early-detection, rapid, real-time, ease-of-us...
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Article
Open AccessStructural basis for the biosynthesis of lovastatin
Statins are effective cholesterol-lowering drugs. Lovastatin, one of the precursors of statins, is formed from dihydromonacolin L (DML), which is synthesized by lovastatin nonaketide synthase (LovB), with the ...
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Article
Open AccessReal-world evidence and optimization of vocal dysfunction in end-stage renal disease patients with secondary hyperparathyroidism
Patients with end-stage renal disease (ESRD) may demonstrate secondary hyperparathyroidism (SHPT), characterized by parathyroid hormone oversecretion in response to electrolyte imbalance (e.g., hypocalcemia an...
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Article
Open AccessGene expression profiling identifies the role of Zac1 in cervical cancer metastasis
The zinc-finger protein which regulates apoptosis and cell cycle arrest 1 (Zac1), encoded by Plagl1 gene, is a seven-zinc-finger containing transcription factor belonging to the imprinted genome and is express...
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Article
Open AccessAssociation between Plasma N-6 Polyunsaturated Fatty Acids Levels and the Risk of Cardiovascular Disease in a Community-based Cohort Study
Most studies support that saturated fatty acid replacement with polyunsaturated fatty acids (PUFAs) may reduce the risk of cardiovascular diseases (CVDs) and put emphasis on the effects of N-3 PUFAs. The repor...
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Open AccessVacancy cluster in ZnO films grown by pulsed laser deposition
Undoped and Ga-doped ZnO films were grown on c-sapphire using pulsed laser deposition (PLD) at the substrate temperature of 600 °C. Positron annihilation spectroscopy study (PAS) shows that the dominant VZn-relat...
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Open AccessComparative Proteomic Profiling and Biomarker Identification of Traditional Chinese Medicine-Based HIV/AIDS Syndromes
Given the challenges in exploring lifelong therapy with little side effect for human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) cases, there is increasing interest in d...