Skip to main content

4 Result(s)

within **biao Zhan Remove this filter Biomedicine, general Remove this filter

and

  1. No Access

    Chapter

    The Internalization and Intracellular Trafficking of ADCs

    Internalization is thought to be an important process during the antibody-based therapeutics. As ADC internalizes, it is transported to lysosome for degradation and payload is released to target intracellular ...

    Keying Liang, M. Saleem Khan, M. Kalim… in Antibody-Drug Conjugates and Cellular Meta… (2023)

  2. No Access

    Chapter

    Antibody-Drug Conjugates: Basic Concepts and Structures

    Antibody-drug conjugates (ADCs) are new modality of anticancer therapeutics. To enhance the translation, three components of an ADC drug—antibody, linker, and cytotoxin— need to be carefully optimized. The sel...

    **biao Zhan in Antibody-Drug Conjugates and Cellular Metabolic Dynamics (2023)

  3. No Access

    Book

    Antibody-Drug Conjugates and Cellular Metabolic Dynamics

    Shuqing Chen, **biao Zhan (2023)

  4. No Access

    Article

    Efficient development and expression of scFv recombinant proteins against PD-L1 surface domain and potency in cancer therapy

    PD-L1 is a 40 kDa trans-membrane protein of B7 family and an important T cell regulator. Binding of PD-L1 and PD-1 inhibits proliferation and activation of T cell results cell exhaustion. This phenomenon can b...

    Muhammad Kalim, Keying Liang, Muhammad Saleem Iqbal Khan, **biao Zhan in Cytotechnology (2019)