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Article
Deoxynivalenol Detoxification by a Novel Strain of Pichia kudriavzevii via Enzymatic Degradation and Cell Wall Adsorption
Deoxynivalenol (DON) is a mycotoxin that significantly threatens the food and feed industry. Corn steep liquor (CSL) is an acidic byproduct of the corn starch industry, and DON is concentrated in CSL once the ...
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Article
Open AccessHsc70 promotes anti-tumor immunity by targeting PD-L1 for lysosomal degradation
Immune checkpoint inhibition targeting the PD-1/PD-L1 pathway has become a powerful clinical strategy for treating cancer, but its efficacy is complicated by various resistance mechanisms. One of the reasons f...
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Article
Open AccessCo-production of 1,3-propanediol and phage phiKpS2 from the glycerol fermentation by Klebsiella pneumoniae
As an alternative to antibiotics in response to antimicrobial-resistant infections, bacteriophages (phages) are garnering renewed interest in recent years. However, the massive preparation of phage is restrict...
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Article
Organic phosphorus levels change the hyphosphere phoD-harboring bacterial community of Funneliformis mosseae
The phoD-harboring bacterial community is responsible for organic phosphorus (P) mineralization in soil and is important for understanding the interactions between arbuscular mycorrhizal (AM) fungi and phosphate-...
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Article
Open AccessGenetic map** and molecular mechanism behind color variation in the Asian vine snake
Reptiles exhibit a wide variety of skin colors, which serve essential roles in survival and reproduction. However, the molecular basis of these conspicuous colors remains unresolved.
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Chapter and Conference Paper
Fabry-Pérot Interferometer-Based Raman Mirror Position Measurement Method for Cold Atom Gravimeter
Cold atom gravimeter’s measurement accuracy is strongly affected by position stability of Raman mirror. A Raman mirror position measurement method using Fabry-Pérot interferometer for cold atom gravimeter is p...
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Chapter and Conference Paper
An Improved Integrated Navigation Fault Tolerance Algorithm Based on Dynamic Evaluation
Integrated navigation systems often need to work in harsh and complex environments. In this case, the navigation instruments may output wrong information, such as abnormal values and data loss
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Chapter and Conference Paper
Delving into Temporal-Spectral Connections in Spike-LFP Decoding by Transformer Networks
Invasive brain-computer interfaces (iBCIs) have demonstrated great potential in neural function restoration by decoding intention from brain signals for external device control. Spike trains and local field po...
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Article
Open AccessEmbryonic organizer formation disorder leads to multiorgan dysplasia in Down syndrome
Despite the high prevalence of Down syndrome (DS) and early identification of the cause (trisomy 21), its molecular pathogenesis has been poorly understood and specific treatments have consequently been practi...
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Article
Open-Pit Mine Extraction from Very High-Resolution Remote Sensing Images Using OM-DeepLab
Automatic extraction of open-pit mine (OM) areas from very high-resolution (VHR) remote sensing images is important for mineral resource management and monitoring. However, few good results have been achieved ...
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Article
Open AccessToxicology evaluation of overdose hydroxychloroquine on zebrafish (Danio rerio) embryos
Potential risks of treatment with hydroxychloroquine (HCQ) include QT interval prolongation, hypoglycemia, a wide range of neuropsychiatric manifestations, hematotoxicity, and potential genetic defects. HCQ is...
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Article
Open AccessImprovement of 1,3-propanediol production from crude glycerol by co-cultivation of anaerobic and facultative microbes under non-strictly anaerobic conditions
Natural microbial consortia could efficiently produce 1,3-propanediol (1,3-PDO), a most promising bulk biochemical derived from glycerol that can be used as a monomer in the synthesis of polytrimethylene terep...
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Article
Open AccessCorrection to: Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model
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Article
Open AccessIonic liquid-based multi-stage sugaring-out extraction of lactic acid from simulated broth and actual lignocellulosic fermentation broth
In this study, ionic liquid-based sugaring-out extraction was developed to separate lactic acid from the synthetic solution and actual lignocellulosic fermentation broth. Except for [EOHmim]BF4, the ILs with BF4−
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Article
Open AccessThe advanced performance of microbial consortium for simultaneous utilization of glucose and xylose to produce lactic acid directly from dilute sulfuric acid pretreated corn stover
Lignocellulosic feedstocks have attracted much attention as a potential carbon source for lactic acid (LA) production because of their ready availability, sustainability, and renewability. However, there are a...
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Article
An aptly industrialized bioprocess for lactic acid production from corn stover using thermotolerant microbial consortia
Chemical pretreatment of lignocellulosic biomass is a critical step in the conversion of lignocellulose to biofuels and biochemical. The main drawback of this pretreatment process is the formation of inhibitor...
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Article
Open AccessMetformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model
Chaperone-mediated autophagy (CMA) is a lysosome-dependent selective degradation pathway implicated in the pathogenesis of cancer and neurodegenerative diseases. However, the mechanisms that regulate CMA are n...
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Article
High-efficient l-lactic acid production from inedible starchy biomass by one-step open fermentation using thermotolerant Lactobacillus rhamnosus DUT1908
The purpose of this study was to establish a simplified operational process for lactic acid (LA) production from inedible starchy biomass by open fermentation using thermotolerant Lactobacillus rhamnosus DUT1908....
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Article
Open AccessARIH1 signaling promotes anti-tumor immunity by targeting PD-L1 for proteasomal degradation
Cancer expression of PD-L1 suppresses anti-tumor immunity. PD-L1 has emerged as a remarkable therapeutic target. However, the regulation of PD-L1 degradation is not understood. Here, we identify several compou...
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Article
Simultaneous liquefaction, saccharification, and fermentation of l-lactic acid using aging paddy rice with hull by an isolated thermotolerant Enterococcus faecalis DUT1805
Simultaneous liquefaction, saccharification, and fermentation (SLSF) has attracted much attention for the production of bio-based chemicals, including l-lactic acid, due to its high efficiency and low cost. In th...
