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Article
Open AccessMesothelin-based CAR-T cells exhibit potent antitumor activity against ovarian cancer
Ovarian cancer (OC) is characterized by its rapid growth and spread which, accompanied by a low 5-year survival rate, necessitates the development of improved treatments. In ovarian cancer, the selective overe...
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Article
Open AccessQuantitative analysis of choroidal vasculature in central serous chorioretinopathy using ultra-widefield swept-source optical coherence tomography angiography
We aimed to quantitatively compare the choroid blood flow and choroid thickness at the periphery among eyes with central serous chorioretinopathy (CSC), fellow eyes and healthy eyes using ultra-widefield swept...
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Article
Open AccessComparison of swept-source OCTA and indocyanine green angiography in central serous chorioretinopathy
To compare swept-source optical coherence tomography angiography (SS-OCTA) and indocyanine green angiography (ICGA) in patients with central serous chorioretinopathy (CSC).
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Article
Open AccessDevelopment and validation of a nomogram to predict cancer-specific survival of uveal melanoma
Uveal melanoma (UM) is a rare but aggressive cancer, which is the most common primary intraocular malignancy in adults. We aimed to develop and validate a competing risk nomogram to predict cancer-specific sur...
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Article
Open AccessDisparities between IgG4-related kidney disease and extrarenal IgG4-related disease in a case–control study based on 450 patients
We aimed to compare the demographic, clinical and laboratory characteristics between IgG4-related kidney disease (IgG4-RKD+) and extrarenal IgG4-related disease (IgG4-RKD−) in a large Chinese cohort, as well a...
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Article
Open AccessClinical features and relapse risks of IgG4-related ophthalmic disease: a single-center experience in China
IgG4-related ophthalmic disease (IgG4-ROD) is one of the phenotypes of IgG4-related disease (IgG4-RD), and its lesions are mainly located in the ocular. Currently, there are few studies on IgG4-ROD and no stud...
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Article
Open AccessMigration of pre-induced human peripheral blood mononuclear cells from the transplanted to contralateral eye in mice
Retina diseases may lead to blindness as they often afflict both eyes. Stem cell transplantation into the affected eye(s) is a promising therapeutic strategy for certain retinal diseases. Human peripheral bloo...
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Article
Current and emerging treatments based on novel mechanisms for immune thrombocytopenia