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Article
Enhanced Nitriding of 38CrMoAl Steels with Laser Vibrational Excitation of Ammonia
Gas nitriding is a thermochemical surface hardening process that is widely used in industry but suffers from a low decomposition rate of ammonia (NH3) and extremely long processing cycles. To enhance the gas nitr...
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Article
Determination of the genetic diversity and population structure of Vaccinium uliginosum in Northeast China based on the chloroplast matK gene and EST-SSRseq molecular markers
Vaccinium uliginosum Linn. is an important wild fruit resource in China. It is primarily distributed throughout the forest regions of Da **ng’an, **ao **ng’an, and Changbai Mountains. However, to the best of our ...
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Article
Microstructures and Wear Resistance of Mo Coating Fabricated by In Situ Laser-Assisted Plasma Spraying
In order to solve the problems of high porosity and poor wear resistance of molybdenum (Mo) coating deposited by atmospheric plasma spraying (APS), the in situ laser-assisted plasma spraying (LAPS) technology ...
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Article
Open AccessEffect of dapagliflozin on proteomics and metabolomics of serum from patients with type 2 diabetes
Sodium-glucose co-transporter 2 (SGLT2) inhibitors reduced the risk of cardiovascular and renal outcomes in patients with type 2 diabetes (T2D), but the underlying mechanism has not been well elucidated. The c...
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Article
Open AccessMitochondrial genome comparison and phylogenetic analysis of Dendrobium (Orchidaceae) based on whole mitogenomes
Mitochondrial genomes are essential for deciphering the unique evolutionary history of seed plants. However, the rules of their extreme variation in genomic size, multi-chromosomal structure, and foreign seque...
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Article
Open AccessLongitudinal changes in serum adropin levels and liver fat content during liraglutide treatment in newly diagnosed patients with type 2 diabetes mellitus and metabolic dysfunction-associated fatty liver disease
To explore the effect of liraglutide treatment on serum adropin and its relationship to the liver fat content in newly diagnosed patients with type 2 diabetes mellitus (T2DM) and metabolic dysfunction-associat...
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Article
Accelerating the stimuli-responsive bending of a gel using mechanical constraints
Gel bends in response to external stimuli, which has important technical applications ranging from artificial muscle to drug delivery. Here, we predict a simple and effective method to accelerate the bending o...
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Article
Open AccessThe climate changes promoted the chloroplast genomic evolution of Dendrobium orchids among multiple photosynthetic pathways
Dendrobium orchids have multiple photosynthetic pathways, which can be used as a model system for studying the evolution of crassulacean acid metabolism (CAM). In this study, based on the results of the net photo...
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Article
Open AccessCelastrol suppresses colorectal cancer via covalent targeting peroxiredoxin 1
As a terpenoids natural product isolated from the plant Thunder God Vine, Celastrol is widely studied for its pharmacological activities, including anti-tumor activities. The clinical application of Celastrol is ...
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Article
Serum Ferritin Levels Are Associated with Adipose Tissue Dysfunction-Related Indices in Obese Adults
Iron overload is associated with type 2 diabetes and metabolic syndrome. However, little is known about the role of iron status on adipose tissue. We aimed to investigate the association of iron metabolism mar...
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Chapter and Conference Paper
Multi-size Scaled CAM for More Accurate Visual Interpretation of CNNs
The search for decision bases for image classification neural networks is one of the popular research directions in deep neural network interpretability. These studies highlight regions of interest to image cl...
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Article
Open AccessElevated serum Meteorin-like levels in patients with hyperthyroidism
Meteorin-like (Metrnl) is a newly discovered adipomyokine that regulates systemic energy homeostasis. Both thyroid hormones and Metrnl increase energy expenditure and induce browning of adipose tissue. Thus, t...
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Article
Open AccessEvolution patterns of NBS genes in the genus Dendrobium and NBS-LRR gene expression in D. officinale by salicylic acid treatment
Dendrobium officinale Kimura et Migo, which contains rich polysaccharides, flavonoids and alkaloids, is a Traditional Chinese Medicine (TCM) with important economic benefits, while various pathogens have brought ...
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Article
Open AccessAssociation of hyperuricemia with apolipoprotein AI and atherogenic index of plasma in healthy Chinese people: a cross-sectional study
The atherogenic index of plasma (AIP) is a predictor for cardiovascular diseases (CVD), while hyperuricemia is an independent risk factor for a variety of CVD. Apolipoprotein AI has been found to be a protecti...
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Article
Open AccessBlood–brain barrier penetration prediction enhanced by uncertainty estimation
Blood–brain barrier is a pivotal factor to be considered in the process of central nervous system (CNS) drug development, and it is of great significance to rapidly explore the blood–brain barrier permeability...
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Article
Open AccessStudy on the relationship between hormone and Lp(a) in Chinese overweight/obese patients
Obesity is a risk factor for metabolic diseases and often influences hormone change. Lipoprotein (a) (Lp(a)) is associated with various metabolic diseases, but there are few studies on the relationship between...
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Article
Open AccessEffects of geographic isolation on the Bulbophyllum chloroplast genomes
Because chloroplast (cp) genome has more conserved structures than nuclear genome and mitochondrial genome, it is a useful tool in estimating the phylogenetic relationships of plants. With a series of research...
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Article
Open AccessInitial analysis of viral dynamics and circulating viral variants during the mRNA-1273 Phase 3 COVE trial
The mRNA-1273 vaccine for coronavirus disease 2019 (COVID-19) demonstrated 93.2% efficacy in reduction of symptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in the blinded port...
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Article
Open AccessReview of research on loosening of threaded fasteners
Loosening of threaded fasteners is a key failure mode, which is mainly caused by the slippage and friction behaviors on the thread and bearing surfaces, and will affect the integrity and reliability of product...
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Article
Open AccessImproving large-scale biomass and total alkaloid production of Dendrobium nobile Lindl. using a temporary immersion bioreactor system and MeJA elicitation
Dendrobium nobile Lindl. is an important pharmacopeial plant with medicinal and ornamental value. This study sought to provide a technical means for the large-scale production of total alkaloid in D. nobile. Seed...
