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Article
Open AccessGenome-wide development of simple sequence repeats markers and genetic diversity analysis of chayote
Chayote is a high economic crop in the Cucurbitaceae family, playing an important role in food production, disease treatment and the production of degradable materials in industries. Due to the harsh environme...
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Article
Open AccessA ferroptosis-related signature predicts the clinical diagnosis and prognosis, and associates with the immune microenvironment of lung cancer
Targeting ferroptosis-related pathway is a potential strategy for treatment of lung cancer (LC). Consequently, exploration of ferroptosis-related markers is important for treating LC. We collected LC clinical ...
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Article
Open AccessRole of reactive oxygen species in myelodysplastic syndromes
Reactive oxygen species (ROS) serve as typical metabolic byproducts of aerobic life and play a pivotal role in redox reactions and signal transduction pathways. Contingent upon their concentration, ROS product...
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Article
Open AccessCAPN2 correlates with insulin resistance states in PCOS as evidenced by multi-dataset analysis
IR emerges as a feature in the pathophysiology of PCOS, precipitating ovulatory anomalies and endometrial dysfunctions that contribute to the infertility challenges characteristic of this condition. Despite it...
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Article
Open AccessIntegrated proteomics reveals autophagy landscape and an autophagy receptor controlling PKA-RI complex homeostasis in neurons
Autophagy is a conserved, catabolic process essential for maintaining cellular homeostasis. Malfunctional autophagy contributes to neurodevelopmental and neurodegenerative diseases. However, the exact role and...
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Article
An oligopeptide permease, OppABCD, requires an iron–sulfur cluster domain for functionality
Oligopeptide permease, OppABCD, belongs to the type I ABC transporter family. Its role is to import oligopeptides into bacteria for nutrient uptake and to modulate the host immune response. OppABCD consists of...
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Article
Modelling Uncertainties and Sensitivity Analysis of Landslide Susceptibility Prediction under Different Environmental Factor Connection Methods and Machine Learning Models
The utilization of different connection methods between landslides and environmental factors introduces uncertainty in landslide susceptibility prediction (LSP). Investigating and identifying the characteristi...
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Article
Role of APR3 in cancer: apoptosis, autophagy, oxidative stress, and cancer therapy
APR3 (Apoptosis-related protein 3) is a gene that has recently been identified to be associated with apoptosis. The gene is located on human chromosome 2p22.3 and contains both transmembrane and EGF (epidermal gr...
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Article
Open AccessPhysiological, anatomical and quality indexes of root tuber formation and development in chayote (Sechium edule)
Chayote is an underutilized species of Cucurbitaceae. It is rich in nutrients such as protein, minerals, phenols and its extracts have anti-cardiovascular and anti-cancer effects, making it a versatile plant f...
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Article
Open AccessComprehensive analysis identifies CLEC1B as a potential prognostic biomarker in hepatocellular carcinoma
C-type lectin domain family 1 member B (CLEC1B, encoding the CLEC-2 protein), a member of the C-type lectin superfamily, is a type II transmembrane receptor involved in platelet activation, angiogenesis, and i...
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Chapter and Conference Paper
Distributed MPC Based on Distributed Evolutionary Game for Leaderless Formation Control
This paper develops a distributed model predictive control (MPC) algorithm for leaderless formation control problem subject to a time-varying communication topology. The motivation for this algorithm is the c...
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Article
Open AccessCharacterization of pyruvate metabolism and citric acid cycle patterns predicts response to immunotherapeutic and ferroptosis in gastric cancer
Gastric cancer is one of the most common malignancies of the digestive system with a high lethal rate. Studies have shown that inherited and acquired mutations in pyruvate metabolism and citric acid cycle (P-C...
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Article
Open AccessSelenium Mitigates Cd-Induced Oxidative Stress and Photosynthesis Inhibition in Two Cherry Tomato Cultivars
The purpose of this study is to explore the physiological mechanisms underlying the attenuation of Cd toxicity using Se in two cherry tomato cultivars ‘Hanluzhe’ (HLZ) and ‘Lvfeicui’ (LFC), with low and high C...
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Article
Landslide susceptibility prediction using an incremental learning Bayesian Network model considering the continuously updated landslide inventories
Existing studies relating to landslide susceptibility prediction (LSP) either do not pay enough attentions to the continuously updated landslide inventories or use batch learning methods for LSP, resulting in ...
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Article
Open AccessGeospatial characterization of rural settlements and potential targets for revitalization by geoinformation technology
To better implement the Strategy of Rural Revitalization, it is essential to characterize the rural settlements and understand their roles in the socio-environmental interactive system. This paper is hence aim...
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Article
Open AccessFTH promotes the proliferation and renders the HCC cells specifically resist to ferroptosis by maintaining iron homeostasis
Ferroptosis is a newly identified type of programmed cell death, which preferentially targets iron-rich cancer cells such as hepatocellular carcinoma (HCC). Ferritin heavy chain (FTH) is a major iron storing n...
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Article
Open AccessGeoinformation-based landslide susceptibility map** in subtropical area
Map** susceptibility of landslide disaster is essential in subtropical area, where abundant rainfall may trigger landslide and mudflow, causing damages to human society. The purpose of this paper is to propo...
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Article
Open AccessAutophagy deficiency in neurodevelopmental disorders
Autophagy is a cell self-digestion pathway through lysosome and plays a critical role in maintaining cellular homeostasis and cytoprotection. Characterization of autophagy related genes in cell and animal mode...
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Article
Open AccessGlide symmetry protected higher-order topological insulators from semimetals with butterfly-like nodal lines
Most topological insulators (TIs) discovered today in spinful systems can be transformed from topological semimetals (TSMs) with vanishing bulk gap via introducing the spin-orbit coupling (SOC), which manifest...
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Article
Orbital exenteration for conjunctival melanoma: comparison of long-term outcome between individualised and conventional techniques
Growing evidence supports an individualised approach rather than radical surgery for conjunctival melanoma (CM). This study aimed to compare the long-term outcome between individualised and conventional exente...
