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  1. No Access

    Article

    The expression level of Neuronal Calcium Sensor 1 can predict the prognosis of cytogenetically normal AML

    Acute myeloid leukemia (AML) is malignant clonal expansion of myeloid blasts with high heterogeneity and numerous molecular biomarkers have been found to judge the prognosis in some specific classifications of...

    Weilong Zhang, **g Wang, Wei Li, **aoni Liu, Yali Zhao in The Pharmacogenomics Journal (2023)

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    Article

    Global characterization of megakaryocytes in bone marrow, peripheral blood, and cord blood by single-cell RNA sequencing

    Megakaryocytes (MK) are mainly derived from bone marrow and are mainly involved in platelet production. Studies have shown that MK derived from bone marrow may have immune function, and that MK from peripheral...

    Weilong Zhang, Changjian Yan, **aoni Liu, ** Yang, **g Wang in Cancer Gene Therapy (2022)

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    Article

    RDIVpSGP motif of ASPP2 binds to 14-3-3 and enhances ASPP2/k18/14-3-3 ternary complex formulation to promote BRAF/MEK/ERK signal inhibited cell proliferation in hepatocellular carcinoma

    The Apoptosis Stimulating Protein of p53 2 (ASPP2) is a heterozygous insufficient tumor suppressor; however, its molecular mechanism(s) in tumor suppression is not completely understood. ASPP2 plays an essenti...

    Tongwang Yang, Cunle zhu, Ying Shi, Yuntai Shen, Yuxue Gao in Cancer Gene Therapy (2022)

  4. Article

    Open Access

    Knockout of ASPP2 promotes DEN-induced hepatocarcinogenesis via the NF-κB pathway in mice

    Apoptosis-stimulating protein p53 2 (ASPP2) is a member of the p53-binding protein family, which is closely related to tumor development. However, the precise mechanism of ASPP2 in liver inflammation and tumor...

    Shanshan Wang, Buxin Kou, Mengyin Chai, Yuxue Gao, Xuejun Lin in Cancer Gene Therapy (2022)

  5. Article

    Open Access

    Prognosis value of RBBP8 expression in plasma cell myeloma

    Plasma cell myeloma (PCM) secretes monoclonal immunoglobulin (Ig) by clonal plasma cells of abnormal proliferation in the bone marrow. As PCM is incurable, it is necessary to find new biomarkers to predict the...

    Weilong Zhang, Ying Song, Xue He, **aoni Liu, Ye Zhang, Zuozhen Yang in Cancer Gene Therapy (2020)

  6. Article

    Open Access

    High expression of UBE2T predicts poor prognosis and survival in multiple myeloma

    Multiple myeloma (MM) is one of hematological malignancies, characterized by malignant proliferation of plasma cells. Biomarkers play an important role in evaluating the development and prognosis of MM. Ubiqui...

    Weilong Zhang, Ye Zhang, Zuozhen Yang, **aoni Liu, ** Yang in Cancer Gene Therapy (2019)