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Article
Open AccessFN-EDA mediates angiogenesis of hepatic fibrosis via integrin-VEGFR2 in a CD63 synergetic manner
Pathological angiogenesis is an important component of hepatic fibrosis along with fibrous deposition, but its role is not well understood. Here, we demonstrated that fibronectin containing extra domain A(FN-E...
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Article
Develo** Spindlin1 small-molecule inhibitors by using protein microarrays
The use of protein microarrays containing human methyllysine effector molecules enabled discovery of a potent and selective inhibitor of the interaction of the Tudor-domain-containing protein Spindlin1 with H3...
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Article
Open AccessEHMT2 inhibitor BIX-01294 induces apoptosis through PMAIP1-USP9X-MCL1 axis in human bladder cancer cells
BIX-01294, an euchromatic histone-lysine N-methyltransferase 2 (EHMT2) inhibitor, has been reported to induce apoptosis in human neuroblastoma cells and inhibit the proliferation of bladder cancer cells. Howev...