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Article
Open AccessDetermination of anthracnose (Colletotrichum fructicola) resistance mechanism using transcriptome analysis of resistant and susceptible pear (Pyrus pyrifolia)
Anthracnose, mainly caused by Colletotrichum fructicola, leads to severe losses in pear production. However, there is limited information available regarding the molecular response to anthracnose in pears.
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Article
Open AccessTMEM160 promotes tumor immune evasion and radiotherapy resistance via PD-L1 binding in colorectal cancer
The effectiveness of anti-programmed cell death protein 1(PD-1)/programmed cell death 1 ligand 1(PD-L1) therapy in treating certain types of cancer is associated with the level of PD-L1. However, this relation...
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Article
Open AccessGenome-wide identification of GA2ox genes family and analysis of PbrGA2ox1-mediated enhanced chlorophyll accumulation by promoting chloroplast development in pear
Chlorophyll (Chl) is an agronomic trait associated with photosynthesis and yield. Gibberellin 2-oxidases (GA2oxs) have previously been shown to be involved in Chl accumulation. However, whether and how the Pbr...
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Article
Prospective observational study on biomarkers of response in pancreatic ductal adenocarcinoma
Adjuvant chemotherapy benefits patients with resected pancreatic ductal adenocarcinoma (PDAC), but the compromised physical state of post-operative patients can hinder compliance. Biomarkers that identify cand...
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Chapter and Conference Paper
Analysis of Navigation Augmentation Performance Based on LEO Satellite Communication Constellation
With the rapid development of LEO communication constellations, the performance enhancement of existing medium and high orbit constellations has been realized by making full use of the characteristics of LEO c...
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Chapter and Conference Paper
GNSS Carrier Tracking via a Variational Bayesian Adaptive Kalman Filter for High Dynamic Conditions
Under high dynamic conditions, a robust carrier tracking approach is essential for global navigation satellite system (GNSS) receivers. In this paper, the powerful Kalman filter (KF) technique is adopted in GN...
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Article
ATF3-induced activation of NF-κB pathway results in acquired PARP inhibitor resistance in pancreatic adenocarcinoma
Olaparib, an inhibitor of poly-(adenosine diphosphate-ribose) polymerase (PARP), has been shown to have anticancer benefits in patients with pancreatic cancer who have a germline mutation in BRCA1/2. However, ...
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Article
Distribution Patterns of Subgroups of Inhibitory Neurons Divided by Calbindin 1
The inhibitory neurons in the brain play an essential role in neural network firing patterns by releasing γ-aminobutyric acid (GABA) as the neurotransmitter. In the mouse brain, based on the protein molecular ...
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Article
A Novel Mouse Model for Polysynaptic Retrograde Tracing and Rabies Pathological Research
Retrograde tracing is an important method for dissecting neuronal connections and map** neural circuits. Over the past decades, several virus-based retrograde tracers have been developed and have contributed...
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Article
Open AccessA microprotein N1DARP encoded by LINC00261 promotes Notch1 intracellular domain (N1ICD) degradation via disrupting USP10-N1ICD interaction to inhibit chemoresistance in Notch1-hyperactivated pancreatic cancer
The extensively activated Notch signaling pathway in pancreatic cancer cells is important in carcinogenesis, chemoresistance, and recurrence. Targeting this pathway is a promising therapeutic strategy for panc...
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Article
Open AccessPlk1 promotes renal tubulointerstitial fibrosis by targeting autophagy/lysosome axis
The prevalence of chronic kidney disease (CKD) has been increasing over the past decades. However, no effective therapies are available for delaying or curing CKD. Progressive fibrosis is the major pathologica...
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Article
Identification of nsLTP family in Chinese white pear (Pyrus bretschneideri) reveals its potential roles in russet skin formation
Identification of PbLTP genes in pear and functional characterization of PbLTP4 in the transport of suberin monomers of russet skin formation.
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Article
Open AccessAuthenticating GNSS civilian signals: a survey
Civilian services of Global Navigation Satellite System are threatened by spoofing attacks since it is hard to determine the authenticity of a navigation signal with a detailed structure open to the public. Si...
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Chapter
Lianqi Development Co. Ltd. v. Shanghai Baoye Group Corp., Ltd. and Guangzhou Supervision Sakai Intellectual Intelligent Technology Co. Ltd. et al.
Legal action directed at declaring whether the same patent or related patents constitutes non-infringement of patent rights and patent infringement action fall into the scope of separate litigation. In judicia...
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Article
Open AccessAnalysis of GPS P(Y) signal power enhancement based on the observations with a semi-codeless receiver
The Global Position System (GPS) satellites of Block IIR-M and later versions can turn on the signal power enhancement if needed. In recent years, this power enhancement has been triggered several times when t...
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Article
Open AccessEffect of breast milk with or without bacteria on infant gut microbiota
The breast milk microbiome could be a source of infant intestinal microbiota. Several studies have found that some breast milk is extremely low in bacteria or is even sterile. There are limited studies on the ...
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Article
Open AccessDifferences in cognition, short-chain fatty acids and related metabolites in pregnant versus non-pregnant women: a cross-sectional study
Pregnancy induces cognitive reorganization which can lead to mental disorders. The aim of this study is to determine differences in cognitive scores, short-chain fatty acids (SCFAs) and related metabolites bet...
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Article
Open AccessImplementation of multi-mode nursing insulation program for patients receiving surgery for spine tumor: a propensity score-matched analysis
Spinal tumor surgery usually involved long operation time, large area of soft tissue resection and long wound, and was prone to hypothermia during the operation. Therefore, actively promoting insulation and op...
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Chapter and Conference Paper
Hybrid Channel Modeling and Multi-frequency Propagation Characterization for GNSS in Urban Canyons
In order to evaluate the multi-frequency transmission performance of satellite navigation in urban canyon environment, the channel model needs to take into account the difference of multi-frequency transmissio...
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Chapter and Conference Paper
Dispersion Analysis of Ranging-Code Markers Applied to Beidou B1C Signal Based on Chimera
At present, in order to improve the security capabilities of the civil navigation signal system, both Galileo and GPS have proposed a navigation signal authentication scheme. However, there is no civil officia...
