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Article
Open AccessVenous blood parameters in determination of respiratory impairment in amyotrophic lateral sclerosis
This study aimed to investigate the relationship between venous blood parameters and respiratory functions in patients with amyotrophic lateral sclerosis (ALS) and develop a model to predict respiratory impair...
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Article
Pharmacokinetics, Pharmacodynamics and Safety of Janagliflozin in Chinese Type 2 Diabetes Mellitus Patients with Renal Impairment
Janagliflozin is a novel sodium–glucose cotransport-2 inhibitor. Despite its remarkable effect in glycemic control, no systematic research has evaluated the effect of renal impairment (RI) on its pharmacokinet...
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Article
A method to characterize ink performance by line resistance measurement through modeling for direct pen writing
The rational evaluation of carbon-based conductive ink performance is critical to both industrial production and applications. Herein, a model to evaluate writing performance of conductive ink by line resistan...
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Article
Open AccessResidue-specific binding of Ni(II) ions influences the structure and aggregation of amyloid beta (Aβ) peptides
Alzheimer’s disease (AD) is the most common cause of dementia worldwide. AD brains display deposits of insoluble amyloid plaques consisting mainly of aggregated amyloid-β (Aβ) peptides, and Aβ oligomers are li...
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Article
Open AccessDiagnosis of coronary artery disease in patients with type 2 diabetes mellitus based on computed tomography and pericoronary adipose tissue radiomics: a retrospective cross-sectional study
Patients with type 2 diabetes mellitus (T2DM) are highly susceptible to cardiovascular disease, and coronary artery disease (CAD) is their leading cause of death. We aimed to assess whether computed tomography...
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Article
Identification of patients with acute myocardial infarction based on coronary CT angiography: the value of pericoronary adipose tissue radiomics
To determine whether radiomics analysis of pericoronary adipose tissue (PCAT) captured by coronary computed tomography angiography (CCTA) could discriminate acute myocardial infarction (MI) from unstable angin...
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Article
Open AccessDorzagliatin add-on therapy to metformin in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled phase 3 trial
Metformin, the first-line therapy for type 2 diabetes (T2D), decreases hepatic glucose production and reduces fasting plasma glucose levels. Dorzagliatin, a dual-acting orally bioavailable glucokinase activato...
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Article
Dorzagliatin in drug-naïve patients with type 2 diabetes: a randomized, double-blind, placebo-controlled phase 3 trial
Improving glucose sensitivity remains an unmet medical need in treating type 2 diabetes (T2D). Dorzagliatin is a dual-acting, orally bioavailable glucokinase activator that enhances glucokinase activity in a g...
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Article
Identification and virulence characterization of entomopathogenic fungus Lecanicillium attenuatum against the pea aphid Acyrthosiphon pisum (Hemiptera: Aphididae)
An entomopathogenic fungal strain was originally isolated on artificial medium from the corpse of a pea aphid (Acyrthosiphon pisum Harris) collected at **gzhou, China (N30°21′18.15″, E112°08′41.63″). Based on te...
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Article
Bioluminescence Imaging of Colonization and Clearance Dynamics of Brucella Suis Vaccine Strain S2 in Mice and Guinea Pigs
The goal of this study was to develop a plasmid-based lux bio-reporter for use to obtain in vivo images of Brucella suis vaccine strain 2 (B.suis S2) infection with high resolution and good definition.
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Article
The Sintering Process and Reaction Kinetics of Fe–Se System after Ball Milling Treatment
The formation mechanism of superconducting phase β-FeSe during sintering process plays a vital role in determining superconductive properties and understanding the mechanism of superconductivity in the iron-based...
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Article
Open AccessFork head transcription factor is required for ovarian mature in the brown planthopper, Nilaparvata lugens (Stål)
The brown planthopper (BPH), Nilaparvata lugens, is the most devastating rice pest in many areas throughout Asia. The reproductive system of female N. lugens consists of a pair of ovaries with 24-33 ovarioles per...
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Article
Efficient, 62.5 watts all-fiber single-mode 1091 nm MOPA laser
A high power all-fiber single-mode 1091 nm laser is constructed in master oscillator power amplifier (MOPA) configuration. The home-made seed source is an Yb3+-doped fiber ring laser with 22.5 mW maximal output p...
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Article
cDNA cloning and recombinant expression of the general odorant binding protein II from Spodoptera litura
A cDNA encoding the general odorant binding protein II (GOBP II) was isolated from the antennae of Spodoptera litura (SlGOBP II, GenBank Accession No. EU086371) by homologous cloning and rapid amplification of cD...
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Article
On Newman-type rational interpolation to |x| at the Chebyshev nodes of the second kind
Recently Brutman and Passow considered Newman-type rational interpolation to |x| induced by arbitrary set of symmetric nodes in [−1, 1] and gave the general estimation of the approximation error. By their methods...
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Article
A new method of recovering polyhydroxyalkanoate fromAzotobacter chroococcum
After polyhydroxyalkanoate (PHA) fermentation for 42 –48 h by theAzotobacter chroococcum G-3, the PHA content reached more than 75% of the dry weight. Biomass was isolated from culture by centrifugation and pretr...
