52 Result(s)
within
**aoli Zhang
Science, Humanities and Social Sciences, multidisciplinary
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Article
Elevated atherogenic index of plasma associated with stroke risk in general Chinese
The atherogenic index of plasma (AIP) is supposed to be associated with cardiovascular disease (CVD), but there is limited evidence on its longitudinal effect. Our study aimed to explore the associations betwe...
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Article
Open AccessThe thioredoxin system determines CHK1 inhibitor sensitivity via redox-mediated regulation of ribonucleotide reductase activity
Checkpoint kinase 1 (CHK1) is critical for cell survival under replication stress (RS). CHK1 inhibitors (CHK1i’s) in combination with chemotherapy have shown promising results in preclinical studies but have d...
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Article
Association of body mass index with risk of cardiometabolic disease, multimorbidity and mortality: a multi-state analysis based on the Kailuan cohort
To evaluate the association of body mass index (BMI) with risk of first cardiometabolic disease (FCMD), cardiometabolic multimorbidity (CMM) and death.
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Open AccessA short-term forecasting method for photovoltaic power generation based on the TCN-ECANet-GRU hybrid model
Due to the uncertainty of weather conditions and the nonlinearity of high-dimensional data, as well as the need for a continuous and stable power supply to the power system, traditional regression analysis and...
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Open AccessCharacterization of antibiotic resistance genes and mobile genetic elements in Escherichia coli isolated from captive black bears
The objective of this study was to analyze the antimicrobial resistance (AMR) characteristics produced by antibiotic resistance genes (ARGs), mobile genetic elements (MGEs) and gene cassettes in Escherichia coli ...
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Open AccessLarge mechanical properties enhancement in ceramics through vacancy-mediated unit cell disturbance
Tailoring vacancies is a feasible way to improve the mechanical properties of ceramics. However, high concentrations of vacancies usually compromise the strength (or hardness). We show that a high elasticity a...
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Open AccessA natural mutation in the promoter of Ms-cd1 causes dominant male sterility in Brassica oleracea
Male sterility has been used for crop hybrid breeding for a long time. It has contributed greatly to crop yield increase. However, the genetic basis of male sterility has not been fully elucidated. Here, we re...
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Open AccessDeep sequencing of microRNAs reveals circadian-dependent microRNA expression in the eyestalks of the Chinese mitten crab Eriocheir sinensis
MicroRNAs (miRNAs) are small endogenous non-coding RNAs. In crustaceans, miRNAs might be involved in the regulation of circadian rhythms. Many physiological functions of crustaceans including immunity and horm...
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Open AccessIntestinal bacterial community composition of juvenile Chinese mitten crab Eriocheir sinensis under different feeding times in lab conditions
Feeding time is an important factor affecting the physiological activity and feeding rhythm of crustaceans. However, little is known about the factors and mechanisms contributing to variations in feeding time ...
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Open AccessA quartz crystal microbalance method to quantify the size of hyaluronan and other glycosaminoglycans on surfaces
Hyaluronan (HA) is a major component of peri- and extra-cellular matrices and plays important roles in many biological processes such as cell adhesion, proliferation and migration. The abundance, size distribu...
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Open AccessRisk factors associated with preterm birth after IVF/ICSI
In vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) is associated with an increased risk of preterm (33rd–37th gestational week) and early preterm birth (20th–32nd gestational week). The underly...
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Open AccessAuthor Correction: Human m6A-mRNA and lncRNA epitranscriptomic microarray reveal function of RNA methylation in hemoglobin H-constant spring disease
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Article
Association of triglyceride–glucose index with intra- and extra-cranial arterial stenosis: a combined cross-sectional and longitudinal analysis
This study aimed to assess the cross-sectional and longitudinal associations of the triglyceride glucose (TyG) index, a simple surrogate marker of insulin resistance, with intra-cranial and extra-cranial arter...
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Article
Open AccessHuman m6A-mRNA and lncRNA epitranscriptomic microarray reveal function of RNA methylation in hemoglobin H-constant spring disease
The thalassemia of Hemoglobin H-Constant Spring disease (HbH-CS) is the most common type of Thalassemia in non-transfusion thalassemia. Interestingly, the clinical manifestations of the same genotype of thalas...
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Open AccessAuthor Correction: Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessHigher choroidal thickness and lower choriocapillaris blood flow signal density based on optical coherence tomography angiography in diabetics
Diabetes mellitus (DM) is one of the fastest growing chronic diseases in the world and one of the main causes of vision loss. Whether or not diabetic choroidopathy (DC) is involved in the initiation and progre...
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Open AccessGasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo
Burkholderia cenocepacia (B. cenocepacia) is an opportunistic bacterium; causing severe life threatening systemic infections in immunocompromised individuals including cystic fibrosis patients. The lack of gasder...
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Article
Open AccessAutomated synthesis and preliminary evaluation of [18F]FDPA for cardiac inflammation imaging in rats after myocardial infarction
A translocator protein 18 kDa targeted radiotracer, N,N-diethyl-2-(2-(4-[18F]fluorophenyl)-5,7-dimethylpyrazolo[1,5-a] pyrimidin-3-yl) acetamide ([18F]FDPA), was automated synthetized and evaluated for cardiac in...
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Article
Open AccessAkt isoform-specific effects on thyroid cancer development and progression in a murine thyroid cancer model
The Akt family is comprised of three unique homologous proteins with isoform-specific effects, but isoform-specific in vivo data are limited in follicular thyroid cancer (FTC), a PI3 kinase-driven tumor. Prior...
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Open AccessClinical analysis in immunocompetent and immunocompromised patients with pulmonary cryptococcosis in western China
Cryptococcosis is a systemic infection and it may occur in immunocompromised and immunocompetent hosts. In order to better understand the clinical characteristics of patients with PC in different immune status...
