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Article
Numerical simulation of microwave-induced cracking and melting of granite based on mineral microscopic models
This study introduces a coupled electromagnetic–thermal–mechanical model to reveal the mechanisms of microcracking and mineral melting of polymineralic rocks under microwave radiation. Experimental tests valid...
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Article
Open AccessA novel model of ambulatory teaching of residents in general practice in China: a cross-sectional study
This study aims to determine the satisfaction and future training needs of general practice residents participating in a novel model of ambulatory teaching aligned with the specifications for standardized resi...
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Article
The benefits of hypoglycemic therapy for patients with obstructive sleep apnea
Obstructive sleep apnea (OSA) is often associated with glycemic abnormalities. This study is conducted to investigate the effects of hypoglycemic therapy on OSA-related indicators.
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Article
Emotion Regulation of EFL Teachers in Blended Classroom Assessment
Blended classroom assessment (CA) has become commonplace in the post-pandemic era, offering advantages but also presenting challenges for English as a Foreign Language (EFL) teachers. These challenges can impa...
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Article
Open AccessInhibition of IL-17 signaling in macrophages underlies the anti-arthritic effects of halofuginone hydrobromide: Network pharmacology, molecular docking, and experimental validation
Rheumatoid arthritis (RA) is a prevalent autoimmune disease marked by chronic synovitis as well as cartilage and bone destruction. Halofuginone hydrobromide (HF), a bioactive compound derived from the Chinese ...
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Article
Open AccessFamiliarity of teaching skills among general practitioners transfer training trainers in China: a cross-sectional survey
The insufficient number of general practitioners (GPs) is a major challenge facing China’s healthcare system. The purpose of the GP transfer training programme was to provide training for experienced doctors t...
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Article
Open AccessEfficacy and Safety of Single-Pill Combination of Rosuvastatin and Ezetimibe in Chinese Patients with Primary Hypercholesterolemia Inadequately Controlled by Statin Treatment (ROZEL): A Randomized, Double-Blind, Double Dummy, Active-Controlled Phase 3 Clinical Trial
Many patients with primary hypercholesterolemia do not achieve their plasma low-density lipoprotein cholesterol (LDL-C) goals with statin alone under a recommended dose of statin (e.g., 10 mg rosuvastatin) in ...
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Article
Associations Between Reproductive Factors and the Risk of Adult-Onset Asthma: A Prospective Cohort Study of European Ancestry
Multiple studies showed sex discrepancies in the prevalence, incidence, and disease control of asthma. The relationships between different reproductive factors and the risk of asthma in females remain uncertain.
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Article
Open AccessSPY1 inhibits neuronal ferroptosis in amyotrophic lateral sclerosis by reducing lipid peroxidation through regulation of GCH1 and TFR1
Ferroptosis is an iron-dependent cell death with the accumulation of lipid peroxidation and dysfunction of antioxidant systems. As the critical regulator, glutathione peroxidase 4 (GPX4) has been demonstrated ...
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Article
Open AccessDid the general practice residents well adapt to real public health prevention ——a study from the COVID-19 prevention training in China
GP residents’s has the obligation to take task with the public health prevetion. GP residents receive the public health training during their college study period and the residents training.
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Article
Open AccessIntegrative analyses of immune-related biomarkers and associated mechanisms in coronary heart disease
Various studies showed that the effect of immune activation is pro-atherogenic and coronary heart disease (CHD) should therefore be considered an autoimmune disease. This study aimed to identify potential immu...
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Article
Prognostic value of metabolic syndrome in renal structural changes in type 2 diabetes
To investigate the prognostic value of metabolic syndrome (MetS) and its relationship with renal structure changes in patients with type 2 diabetes and associated diabetic nephropathy (DN).
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Article
Carboxylated cellulose nanocrystals as environmental-friendly and multi-functional additives for bentonite water-based drilling fluids under high-temperature conditions
During the oil and gas drilling engineering, the selection of drilling fluids must take account of the technical and environmental factors. This study investigated the effectiveness of carboxylated cellulose n...
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Article
Experimental studies on physical and mechanical behaviors of heated rocks with pre-fabricated hole exposed to different cooling rates
In enhanced geothermal systems, thermal shock occurs around the borehole when cold water is injected into the hot rock of a geothermal reservoir. Experiments were performed on granite and sandstone specimens t...
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Article
Open AccessPrevalence and correlates of disability among urban–rural older adults in Southwest China: a large, population-based study
As one of the challenges of aging, older adults with disabilities are often overlooked in remote areas of many develo** countries, including southwest China. Similar populations would undoubtedly benefit fro...
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Article
Open AccessSystematic analysis of prognostic significance, functional enrichment and immune implication of STK10 in acute myeloid leukemia
Despite deeper understanding of the genetic landscape of acute myeloid leukemia (AML), the improvement of survival is still a great challenge. STK10 is overexpressed in several cancers with functions varying acco...
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Article
Movement process analysis of the high-speed long-runout Shuicheng landslide over 3-D complex terrain using a depth-averaged numerical model
Flow-like landslide is one of the most catastrophic types of natural hazards due to its high velocity and long travel distance. In 2019, a large catastrophic landslide was triggered by heavy rainfall and occur...
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Article
Open AccessA cross-national analysis of cultural representations in English textbooks used in China and Germany
Culture learning is complicated in teaching English as an international language (EIL), given the global contexts in which English is being used for various purposes. This study aims to examine cultural repres...
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Article
Serum adropin level is associated with endothelial dysfunction in patients with obstructive sleep apnea and hypopnea syndrome
Adropin is a recently discovered peptide hormone that plays a vital role in metabolism and cardiovascular-cerebrovascular function. The purpose of this study is to investigate the role of circulating adropin l...
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A Coupled Discrete Element and Depth-Averaged Model for Flow-Like Landslide Simulations
Flow-like landslides commonly happen in mountainous areas and may cause economic and human life losses in the impacted areas. Computer modelling has become an effective tool for landslide risk assessment and r...