39 Result(s)

Article

Improving the accuracy of genomic prediction in dairy cattle using the biologically annotated neural networks framework

Biologically annotated neural networks (BANNs) are feedforward Bayesian neural network models that utilize partially connected architectures based on SNP-set annotations. As an interpretable neural network, BA...

Xue Wang, Shaolei Shi, Md. Yousuf Ali Khan… in Journal of Animal Science and Biotechnology (2024)

Article

De novo genome assembly of a high-protein soybean variety HJ117

Soybean is an important feed and oil crop in the world due to its high protein and oil content. China has a collection of more than 43,000 soybean germplasm resources, which provides a rich genetic diversity f...

Zhi Liu, Qing Yang, Bingqiang Liu, Chenhui Li, **aolei Shi, Yu Wei… in BMC Genomic Data (2024)

Article

Correction: Mesenchymal stem cell-secreted prostaglandin E2 ameliorates acute liver failure via attenuation of cell death and regulation of macrophage polarization

**glin Wang, Yang Liu, Haoran Ding, **aolei Shi… in Stem Cell Research & Therapy (2023)

Article

Number of recurrences is significantly associated with the post-acute pancreatitis diabetes mellitus in a population with hypertriglyceridemic acute pancreatitis

Twenty-three percent of patients are diagnosed with diabetes mellitus after the first episode of acute pancreatitis. The incidence of post-acute pancreatitis diabetes mellitus is significantly higher than that...

**amin Tu, Qingxie Liu, Lin Chen, Jie Li, ** Yu… in Lipids in Health and Disease (2023)

Article

Integrative transcriptome and proteome analyses of clear cell renal cell carcinoma develop a prognostic classifier associated with thrombus

Clear cell renal cell carcinoma (ccRCC) with venous tumor thrombus (VTT) is associated with poor prognosis. Our integrative analyses of transcriptome and proteome reveal distinctive molecular features of ccRCC...

**aolei Shi, Qingyang Pang, **nwen Nian, Aimin Jiang, Haoqing Shi… in Scientific Reports (2023)

Article

ALAN is a computational approach that interprets genomic findings in the context of tumor ecosystems

Gene behavior is governed by activity of other genes in an ecosystem as well as context-specific cues including cell type, microenvironment, and prior exposure to therapy. Here, we developed the Algorithm for ...

Hannah E. Bergom, Ashraf Shabaneh, Abderrahman Day, Atef Ali… in Communications Biology (2023)

Article

Human endoderm stem cells reverse inflammation-related acute liver failure through cystatin SN-mediated inhibition of interferon signaling

Acute liver failure (ALF) is a life-threatening disease that occurs secondary to drug toxicity, infection or a devastating immune response. Orthotopic liver transplantation is an effective treatment but limite...

Yilin Xu, **glin Wang, Haozhen Ren, Hao Dai, Ying Zhou, **ongzhao Ren… in Cell Research (2023)

Chapter and Conference Paper

3D Printing of Hydrogel-Based Seed Planter for In-Space Seed Nursery

Interest in manufacturing parts using 3D printing became popular across academic and industrial sectors because of its improved reliability and accessibility. With the necessity of self-sustentation, growing p...

Yanhua Huang, Li Yu, Liangkui Jiang… in Flexible Automation and Intelligent Manufa… (2023)

Article

Correction: Hepatocellular carcinoma-derived exosomal miRNA-21 contributes to tumor progression by converting hepatocyte stellate cells tocancer-associated fibroblasts

Yuan Zhou, Haozhen Ren, Bo Dai, Jun Li… in Journal of Experimental & Clinical Cancer … (2022)

Article

Comparative epigenomics reveals the impact of ruminant-specific regulatory elements on complex traits

Insights into the genetic basis of complex traits and disease in both human and livestock species have been achieved over the past decade through detection of genetic variants in genome-wide association studie...

Siqian Chen, Shuli Liu, Shaolei Shi, Yifan Jiang, Mingyue Cao, Yongjie Tang… in BMC Biology (2022)

Article

Integrative molecular analyses define correlates of high B7-H3 expression in metastatic castrate-resistant prostate cancer

B7-H3 (CD276) is an immune checkpoint overexpressed in prostate cancer with minimal expression in normal tissues and associated with poor prognosis, making it an excellent therapy target. We interrogated B7-H3...

**aolei Shi, Abderrahman Day, Hannah E. Bergom, Sydney Tape… in npj Precision Oncology (2022)

Article

The associations between plasma soluble Trem1 and neurological diseases: a Mendelian randomization study

Triggering receptor expressed on myeloid cell 1 (Trem1) is an important regulator of cellular inflammatory responses. Neuroinflammation is a common thread across various neurological diseases. Soluble Trem1 (s...

**aolei Shi, Tao Wei, Yachun Hu, Meng Wang, Yi Tang in Journal of Neuroinflammation (2022)

Article

Antibiotic pretreatment attenuates liver ischemia–reperfusion injury by Farnesoid X receptor activation

Prophylactic antibiotics (Abx) are used before liver surgery, and the influence of antibiotic pretreatment on hepatic ischemia–reperfusion injury (IRI) remains unclear. Hence, we explored the impact of Abx pre...

Hanyi Liu, **glin Wang, Yitao Ding, **aolei Shi, Haozhen Ren in Cell Death & Disease (2022)

Article

Using machine learning to improve the accuracy of genomic prediction of reproduction traits in pigs

Recently, machine learning (ML) has become attractive in genomic prediction, but its superiority in genomic prediction over conventional (ss) GBLUP methods and the choice of optimal ML methods need to be inves...

Xue Wang, Shaolei Shi, Guijiang Wang… in Journal of Animal Science and Biotechnology (2022)

Article

CircZDBF2 up-regulates RNF145 by ceRNA model and recruits CEBPB to accelerate oral squamous cell carcinoma progression via NFκB signaling pathway

Oral squamous cell carcinoma (OSCC), as one of the commonest malignancies showing poor prognosis, has been increasingly suggested to be modulated by circular RNAs (circRNAs). Through GEO (Gene Expression Omnib...

Liang Rong, Bo Chen, Ke Liu, Bingyao Liu, **nyao He… in Journal of Translational Medicine (2022)

Article

Author Correction: Skill levels and gains in university STEM education in China, India, Russia and the United States

A Correction to this paper has been published: https://doi.org/10.1038/s41562-021-01102-y.

Prashant Loyalka, Ou Lydia Liu, Guirong Li, Elena Kardanova… in Nature Human Behaviour (2021)

Article

Prognostic nomogram for hepatocellular carcinoma with radiofrequency ablation: a retrospective cohort study

Radiofrequency ablation (RFA) is an effective treatment option for hepatocellular carcinoma (HCC). This study aimed to analyze the prognostic factors of HCC patients treated with RFA and to develop nomograms f...

Zhenhua Lu, Zhen Sun, Chengyu Liu, **aolei Shi, Rui Li, Weiwei Shao… in BMC Cancer (2021)

Article

Circulating exosomal mRNA profiling identifies novel signatures for the detection of prostate cancer

The landscape and characteristics of circulating exosomal messenger RNAs (emRNAs) are poorly understood, which hampered the accurate detection of circulating emRNAs. Through comparing RNA sequencing data of ci...

** Ji, Rui Chen, Lin Zhao, Yalong Xu, Zhi Cao, Huan Xu, ** Chen… in Molecular Cancer (2021)

Article

Mesenchymal stem cell-secreted prostaglandin E₂ ameliorates acute liver failure via attenuation of cell death and regulation of macrophage polarization

Acute liver failure (ALF) is an acute inflammatory liver disease with high mortality. Previous preclinical and clinical trials have confirmed that mesenchymal stem cell (MSC) is a promising therapeutic approac...

**glin Wang, Yang Liu, Haoran Ding, **aolei Shi… in Stem Cell Research & Therapy (2021)

Article

KDM6B is an androgen regulated gene and plays oncogenic roles by demethylating H3K27me3 at cyclin D1 promoter in prostate cancer

Lysine (K)-specific demethylase 6B (KDM6B), a stress-inducible H3K27me3 demethylase, plays oncogenic or antitumoral roles in malignant tumors depending on the type of tumor cell. However, how this histone modi...

Zhi Cao, **aolei Shi, Feng Tian, Yu Fang, Jason Boyang Wu… in Cell Death & Disease (2021)