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Article
Open AccessA molecular subty** associated with the cGAS-STING pathway provides novel perspectives on the treatment of ulcerative colitis
Ulcerative colitis (UC) is characterized by an abnormal immune response, and the pathogenesis lacks clear understanding. The cGAS-STING pathway is an innate immune signaling pathway that plays a significant ro...
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Article
Modulation of histone acetylation enables fully mechanized hybrid rice breeding
Hybrid rice has achieved high grain yield and greatly contributes to food security, but the manual-labour-intensive hybrid seed production process limits fully mechanized hybrid rice breeding. For next-generat...
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Article
Integration of multiomics analyses reveals unique insights into CD24-mediated immunosuppressive tumor microenvironment of breast cancer
Tumor immunotherapy brings new light and vitality to breast cancer patients, but low response rate and limitations of therapeutic targets become major obstacles to its clinical application. Recent studies have...
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Article
Open AccessMRI radiomics based on deep learning automated segmentation to predict early recurrence of hepatocellular carcinoma
To investigate the utility of deep learning (DL) automated segmentation-based MRI radiomic features and clinical-radiological characteristics in predicting early recurrence after curative resection of single h...
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Article
Synthesis of Novel High-Performance Adsorbent Based on Modified Polyurethane/Polysaccharidesfor Wastewater Treatment
Water pollution caused by harmful bacteria, heavy metals and dye is a global issue that requires strategic solutions to minimize its environmental impact. In this work, novel polysaccharide-modified polyuretha...
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Article
Mechanism of efficient adsorption for arsenic in aqueous solution by zeolitic imidazolate framework‑8
Arsenic (As) is one extremely hazardous and carcinogenic metalloid element. Due to mining, metal smelting, and other human activities, the pollution of water (especially groundwater) and soil caused by As is i...
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Article
Deep learning-based arterial subtraction images improve the detection of LR-TR algorithm for viable HCC on extracellular agents-enhanced MRI
To determine the role of deep learning-based arterial subtraction images in viability assessment on extracellular agents-enhanced MRI using LR-TR algorithm.
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Article
Aspect category sentiment classification via document-level GAN and POS information
The purpose of aspect-category sentiment classification (ACSC) is to determine the sentiment polarity of the predefined aspect category from the texts. Current methods for ACSC have two main limitations. Since...
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Article
Manipulable, reversible and diversified de-identification via face identity disentanglement
Face de-identification has always been a focal point in privacy-preserving research. Most existing de-identification methods focus only on the anonymization phase, neglecting the importance of deanonymization....
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Open AccessThe learning curve of the MS-TRAM/DIEP breast reconstruction by dual-trained breast surgeons
Breast cancer surgeries involving MS-TRAM/DIEP breast reconstruction has traditionally been collaborative efforts between breast surgeons and plastic surgeons. However, in our institution, this procedure is pe...
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Article
Accumulation of heavy metals in rice and the microbial response in a contaminated paddy field
Microorganisms play an important role in soil chemical cycling and ecological persistence. However, the effects and mechanisms of microorganisms on the accumulation of heavy metals in soils and rice grains are...
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Article
RAB27B-regulated exosomes mediate LSC maintenance via resistance to senescence and crosstalk with the microenvironment
The fate of leukaemia stem cells (LSCs) is determined by both their inherent mechanisms and crosstalk with their niches. Although LSCs were confirmed to be eradicated by restarting senescence, the specific key...
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Article
The Mechanism of Arsenic-Contaminated Soil Remediation by Immobilized Achromobacter sp. HC3
The potential of immobilized microbial technology as a solution to arsenic (As) soil contamination is underexplored, despite its promising prospects. This research employed sodium alginate-silkworm excrement b...
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Article
Open AccessFollicular fluid C3a-peptide promotes oocyte maturation through F-actin aggregation
Immature cumulus-oocyte complexes are retrieved to obtain mature oocytes by in vitro maturation (IVM), a laboratory tool in reproductive medicine to obtain mature oocytes. Unfortunately, the efficiency of IVM ...
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Article
Open AccessA breast cancer classification and immune landscape analysis based on cancer stem-cell-related risk panel
This study sought to identify molecular subtypes of breast cancer (BC) and develop a breast cancer stem cells (BCSCs)-related gene risk score for predicting prognosis and assessing the potential for immunother...
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Article
A novel immune checkpoint-related signature for prognosis and immune analysis in breast cancer
Breast cancer is one of the most prevailing forms of cancer globally. Immunotherapy has demonstrated efficacy in improving the overall survival of breast cancer. The aim of us was to formulate a novel signatur...
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Article
Development of interface haze after femtosecond laser-assisted in situ keratomileusis with accelerated corneal crosslinking: a case series
Femtosecond laser-assisted in situ keratomileusis (FS-LASIK) with accelerated corneal crosslinking (FS-LASIK Xtra) is a recent procedure to achieve safer corneal ablation in myopic patients with borderline cor...
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Article
Open AccessShared biomarkers and immune cell infiltration signatures in ulcerative colitis and nonalcoholic steatohepatitis
The coexistence of ulcerative colitis (UC) and nonalcoholic steatohepatitis (NASH) involves a intricate interplay, though the precise pathophysiological mechanisms remain elusive. To shed light on this, our st...
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Article
Open AccessHuman umbilical cord mesenchymal stem cells ameliorate colon inflammation via modulation of gut microbiota-SCFAs-immune axis
Inflammatory bowel disease (IBD) is a global health problem in which gut microbiota dysbiosis plays a pivotal pathogenic role. Mesenchymal stem cells (MSCs) therapy has emerged as a prospective novel tool for ...
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Article
Stability Mechanism of Hexavalent Chromium Reduction by Nano-zerovalent Iron Under Different Environments
Nanoscale zero-valent iron (NZVI) has a promising application in the remediation of hexavalent chromium in aqueous environments, but its stability in the remediation environment has rarely been investigated. I...
