9 Result(s)
within
**aojuan Chen
Science, Humanities and Social Sciences, multidisciplinary
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Article
Diabetes in a Weiss-Kruszka syndrome boy and a de novo deletion in 9q31.2
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Article
Open AccessStructures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity
Mitochondrial apoptosis is strictly controlled by BCL-2 family proteins through a subtle network of protein interactions. The tumor suppressor protein p53 triggers transcription-independent apoptosis through d...
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Article
Open AccessIdentification of cuproptosis-related lncRNA for predicting prognosis and immunotherapeutic response in cervical cancer
Patients diagnosed with advanced cervical cancer (CC) have poor prognosis after primary treatment, and there is a lack of biomarkers for predicting patients with an increased risk of recurrence of CC. Cupropto...
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Open AccessFunctional and metabolic alterations of gut microbiota in children with new-onset type 1 diabetes
Gut dysbiosis has been linked to type 1 diabetes (T1D); however, microbial capacity in T1D remains unclear. Here, we integratively profiled gut microbial functional and metabolic alterations in children with n...
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Open AccessStructural insight into the ligand binding mechanism of aryl hydrocarbon receptor
The aryl hydrocarbon receptor (AHR), a member of the basic helix–loop–helix (bHLH) Per–Arnt–Sim (PAS) family of transcription factors, plays important roles in regulating xenobiotic metabolism, cellular differ...
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Open AccessStructural insight into the molecular mechanism of p53-mediated mitochondrial apoptosis
The tumor suppressor p53 is mutated in approximately half of all human cancers. p53 can induce apoptosis through mitochondrial membrane permeabilization by interacting with and antagonizing the anti-apoptotic ...
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Open AccessComparative mitochondrial genome analysis reveals intron dynamics and gene rearrangements in two Trametes species
Trametes species are efficient wood decomposers that are widespread throughout the world. Mitogenomes have been widely used to understand the phylogeny and evolution of fungi. Up to now, two mitogenomes from the
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Article
Open AccessA phytic acid derived LiMn0.5Fe0.5PO4/Carbon composite of high energy density for lithium rechargeable batteries
A composite of olivine lithium manganese iron phosphate (LiMn0.5Fe0.5PO4), external carbon coating and internal embedded carbon flakes, EC-IC-LMFP, is prepared by using phytic acid (PhyA) as phosphorus source via
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Article
Open AccessRetinoic acid facilitates inactivated transmissible gastroenteritis virus induction of CD8+ T-cell migration to the porcine gut
The digestive tract is the entry site for transmissible gastroenteritis virus (TGEV). TGEV transmission can be prevented if local immunity is established with increased lymphocytes. The current parenteral mode...
