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9 Result(s)

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  1. No Access

    Article

    Pediatric acute myeloid leukemia and hyperleukocytosis with WBC count greater than 50 × 109/L

    Acute myeloid leukemia (AML) and hyperleukocytosis have an unfavorable prognosis, but the impact of hyperleukocytosis on the prognosis of pediatric AML remains uncertain. We investigated the clinical character...

    Aoli Zhang, Lipeng Liu, Suyu Zong, Lixian Chang… in International Journal of Hematology (2023)

  2. No Access

    Article

    Short-term efficacy of decitabine-based therapy in JMML: a retrospective study from a single center in China

    Juvenile myelomonocytic leukemia (JMML) is an aggressive pediatric myeloproliferative disease, and newly diagnosed patients frequently cannot tolerate hematopoietic stem cell transplantation (HSCT) at diagnosi...

    Yuli Cai, **gliao Zhang, Meihui Yi, Wenfeng Zhang… in International Journal of Hematology (2023)

  3. No Access

    Article

    Low absolute neutrophil count during induction therapy is an adverse prognostic factor in childhood acute lymphoblastic leukaemia

    Variation in normal blood cells during chemotherapy has not been recognised as a risk factor guiding chemotherapy in childhood acute lymphoblastic leukaemia (ALL). This study aims to explore whether variations...

    **aoyan Chen, Chao Liu, Aoli Zhang, WenQi Wu, Lipeng Liu, Yang Lan… in Annals of Hematology (2021)

  4. No Access

    Article

    Early T-cell precursor acute lymphoblastic leukemia and other subtypes: a retrospective case report from a single pediatric center in China

    Early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) is rare in China and case reports are varied. We conducted an in-depth analysis of newly diagnosed children with T-ALL from January 1999 to April 2...

    **aoming Liu, Yao Zou, Li Zhang… in Journal of Cancer Research and Clinical On… (2021)

  5. No Access

    Article

    Long-term safety and efficacy of imatinib in pediatric patients with chronic myeloid leukemia: single-center experience from China

    Chronic myeloid leukemia (CML) is a rare disease among children. A retrospective study was conducted from November 2002 to March 2019 at a single institution in China. A total of 36 pediatric CML patients (25 ...

    Yuli Cai, Chao Liu, Ye Guo, **aojuan Chen, Li Zhang… in International Journal of Hematology (2021)

  6. Article

    Open Access

    FGFR-TKI resistance in cancer: current status and perspectives

    Fibroblast growth factor receptors (FGFRs) play key roles in promoting the proliferation, differentiation, and migration of cancer cell. Inactivation of FGFRs by tyrosine kinase inhibitors (TKI) has achieved g...

    Sitong Yue, Yukun Li, **aojuan Chen, Juan Wang… in Journal of Hematology & Oncology (2021)

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  7. Article

    Open Access

    Efficacy and safety of CD19 CAR T constructed with a new anti-CD19 chimeric antigen receptor in relapsed or refractory acute lymphoblastic leukemia

    Recent evidence suggests that resistance to CD19 chimeric antigen receptor (CAR)-modified T cell therapy may be due to the presence of CD19 isoforms that lose binding to the single-chain variable fragment (scF...

    Runxia Gu, Fang Liu, Dehui Zou, Yingxi Xu, Yang Lu… in Journal of Hematology & Oncology (2020)

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  8. No Access

    Article

    Clinical features, mutations and treatment of 104 patients of Diamond-Blackfan anemia in China: a single-center retrospective study

    Diamond-Blackfan anemia (DBA) is an inherited bone marrow failure syndrome characterized by a paucity of erythroid progenitors. We summarized the clinical and genetic features of 104 DBA patients in a single-c...

    Yang Wan, **aojuan Chen, Wenbin An, Min Ruan… in International Journal of Hematology (2016)

  9. No Access

    Article

    Effect of arsenic trioxide on the treatment of children with newly diagnosed acute promyelocytic leukemia in China

    To explore the efficacy of treatment for childhood acute promyelocytic leukemia (APL) with a combination of all-trans-retinoic acid (ATRA) and arsenic trioxide (As2O3) for remission induction, we reviewed the cli...

    Li Zhang, **aofan Zhu, Yao Zou, Yumei Chen… in International Journal of Hematology (2011)