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109 Result(s)
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Article
Diabetes in a Weiss-Kruszka syndrome boy and a de novo deletion in 9q31.2
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Article
Corneal endothelial morphology changes in patients with proliferative diabetic retinopathy
Diabetes patients often suffer from diabetes keratopathy in the course of their illness. The examination of corneal endothelium in proliferative diabetic retinopathy (PDR) patients has important clinical signi...
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Article
Open AccessStructural basis and selectivity of sulfatinib binding to FGFR and CSF-1R
Acquired drug resistance poses a challenge for single-target FGFR inhibitors, leading to the development of dual- or multi-target FGFR inhibitors. Sulfatinib is a multi-target kinase inhibitor for treating neu...
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Chapter and Conference Paper
Research on the Performance of Concrete Mix Ratio Based on Artificial Intelligence Optimization Algorithm
With the development of computer informatization, various fields of engineering have gradually realized information means. The concrete mix ratio involves many parameters, and the mutual influence relationship...
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Article
Meta-analysis of correlation between sleep duration and gender difference in adults with type 2 diabetes
To explore the correlation between sleep duration and type II diabetes in adults.
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Article
Pediatric acute myeloid leukemia and hyperleukocytosis with WBC count greater than 50 × 109/L
Acute myeloid leukemia (AML) and hyperleukocytosis have an unfavorable prognosis, but the impact of hyperleukocytosis on the prognosis of pediatric AML remains uncertain. We investigated the clinical character...
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Article
A primary amoebic meningoencephalitis case associated with swimming in seawater
This case report describes a 62-year-old male fisherman who presented with persistent vomiting, headache, and behavior changes. Despite initial antibiotic and corticosteroid treatment, his condition worsened, ...
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Article
Open AccessStructures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity
Mitochondrial apoptosis is strictly controlled by BCL-2 family proteins through a subtle network of protein interactions. The tumor suppressor protein p53 triggers transcription-independent apoptosis through d...
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Article
Open AccessIdentification of cuproptosis-related lncRNA for predicting prognosis and immunotherapeutic response in cervical cancer
Patients diagnosed with advanced cervical cancer (CC) have poor prognosis after primary treatment, and there is a lack of biomarkers for predicting patients with an increased risk of recurrence of CC. Cupropto...
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Article
Open AccessGreen construction and release mechanism of lignin-based double-layer coated urea
Lignin played an important role in the establishment of coated fertilizers coating material as a substitute for petrochemical raw materials. However, so far, the lignin-based coated fertilizers was limited in ...
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Article
Ezrin accelerates breast cancer liver metastasis through promoting furin-like convertase-mediated cleavage of Notch1
Ezrin, known as a crosslinker between the plasma membrane and actin cytoskeleton, is closely associated with breast cancer (BC) progression. Here, we explored a novel role of ezrin in breast cancer liver metas...
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Article
Open AccessCorrection to: Knockdown of heat shock protein family D member 1 (HSPD1) promotes proliferation and migration of ovarian cancer cells via disrupting the stability of mitochondrial 3-oxoacyl-ACP synthase (OXSM)
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Article
Synthesis of silicone blocked bio-polyurethane and its application in highly stretchable fiber-shaped strain sensor
Flexible strain sensors have become a key component of intelligent wearable electronics. However, the fabrication of strain sensors with wide workable strain ranges and high sensitivity remains a great challen...
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Article
Hypoxia-responsive PPARGC1A/BAMBI/ACSL5 axis promotes progression and resistance to lenvatinib in hepatocellular carcinoma
Emerging evidence has indicated that peroxisome proliferator-activated receptor-gamma coactivator-1α (PPARGC1A) is involved in hepatocellular carcinoma (HCC). However, its detailed function and up- and downstr...
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Article
Selection of the appropriate reference genes by quantitative real-time PCR in leopard coral groupers Plectropomus leopardus
Leopard coral groupers (Plectropomus leopardus), commercially bred in South China, are a significant economical fish species. In this study, by means of quantitative real-time PCR (qRT-PCR) technology, we assesse...
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Article
Open AccessEfficacy of preemptive intercostal nerve block on recovery in patients undergoing video-assisted thoracic lobectomy
Preemptive intercostal nerve block (pre-ICNB) achieves the same analgesic effects as postoperative ICNB (post-ICNB) remains unclear. This study aimed to evaluate the efficacy of preemptive ICNB on perioperativ...
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Article
Open AccessKnockdown of heat shock protein family D member 1 (HSPD1) promotes proliferation and migration of ovarian cancer cells via disrupting the stability of mitochondrial 3-oxoacyl-ACP synthase (OXSM)
Heat shock protein 60 (HSP60) is essential for the folding and assembly of newly imported proteins to the mitochondria. HSP60 is overexpressed in most types of cancer, but its association with ovarian cancer i...
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Article
The impacts of climate change on regional temperature characteristics and climate zones
Global warming can lead to a more frequent occurrence of hot days and heat waves and fewer cold days and cold waves. In this paper, the daily mean temperature (TM) was divided into 7 range categories (TM < − ...
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Article
Short-term efficacy of decitabine-based therapy in JMML: a retrospective study from a single center in China
Juvenile myelomonocytic leukemia (JMML) is an aggressive pediatric myeloproliferative disease, and newly diagnosed patients frequently cannot tolerate hematopoietic stem cell transplantation (HSCT) at diagnosi...
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Protocol
Vascularized Islet Transplantation as Composite Islet-Kidney Grafts with Nanoparticle-Labeled Islets in Large Animal Preclinical Transplant Models
Although there are many patients with diabetes and end-stage renal failure (DM/ESRD) who would benefit from a transplantation strategy that addresses both their ESRD and its underlying cause, current methods o...