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Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression

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  1. Article

    Open Access

    Targeting HIC1/TGF-β axis-shaped prostate cancer microenvironment restrains its progression

    Prostate cancer (PCa) is a malignant tumor that seriously threatens men’s health worldwide. Recently, stromal cells in the tumor microenvironment (TME) have been reported to contribute to the progression of PC...

    Tianqi Wu, Wenfeng Wang, Guohai Shi, Mingang Hao, Yingying Wang… in Cell Death & Disease (2022)

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  2. Article

    Open Access

    LINC00675 activates androgen receptor axis signaling pathway to promote castration-resistant prostate cancer progression

    The development of prostate cancer (PCa) from androgen-deprivation therapy (ADT) sensitive to castration resistant (CRPC) seriously impacts life quality and survival of PCa patients. Emerging evidence shows th...

    Mengfei Yao, **aolei Shi, Yue Li, Yutian **ao, William Butler… in Cell Death & Disease (2020)

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  3. Article

    Open Access

    Microvesicles and chemokines in tumor microenvironment: mediators of intercellular communications in tumor progression

    Increasing evidence indicates that the ability of cancer cells to convey biological information to recipient cells within the tumor microenvironment (TME) is crucial for tumor progression. Microvesicles (MVs) ...

    **aojie Bian, Yu-Tian **ao, Tianqi Wu, Mengfei Yao, Leilei Du… in Molecular Cancer (2019)

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  4. Article

    Open Access

    TNF-α sensitizes chemotherapy and radiotherapy against breast cancer cells

    Despite new developments in cancer therapy, chemotherapy and radiotherapy remain the cornerstone of breast cancer treatment. Therefore, finding ways to reduce the toxicity and increase sensitivity is particula...

    **ao Wu, Meng-Yao Wu, Min Jiang, Qiaoming Zhi, **aojie Bian… in Cancer Cell International (2017)

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