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Article
Open AccessIdentification of an HLA-A*11:01-restricted neoepitope of mutant PIK3CA and its specific T cell receptors for cancer immunotherapy targeting hotspot driver mutations
Hotspot driver mutations presented by human leukocyte antigens might be recognized by anti-tumor T cells. Based on their advantages of tumor-specificity and immunogenicity, neoantigens derived from hotspot mut...
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Article
Open AccessPotent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants
Accumulating mutations in the SARS-CoV-2 Spike (S) protein can increase the possibility of immune escape, challenging the present COVID-19 prophylaxis and clinical interventions. Here, 3 receptor binding domai...
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Article
Efficient Removal of Dyes from Aqueous Solution by a Porous Sodium Alginate/gelatin/graphene Oxide Triple-network Composite Aerogel
A three-dimensional (3D) robust sodium alginate/gelatin/graphene oxide (SGGO) triple-network composite aerogel was designed using a “hydrophilic assembly–sustained release gelation” two-step method. The result...
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Article
Wrinkling prediction of aluminum alloy tubes during reduced diameter compression forming
Wrinkling is a significant challenge associated with the forming of tubes via diameter reduction. The work reported herein employed elastoplastic principles to assess the external pressure diameter reduction f...
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Article
Inhibitor of DNA Binding-1 Overexpression in Prostate Cancer: Relevance to Tumor Differentiation
Inhibitor of DNA binding-1 (Id1) is a dominant-negative regulator of basic helix–loop–helix transcription factor, which control malignant cell behaviors in several types of carcinomas. This study aimed to find...