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Open AccessEffect of Infusion Set Replacement Intervals on Central Line-Associated Bloodstream Infection in the Intensive Care Unit: Study Protocol of the INSPIRATION Study
The replacement intervals for infusion sets may differ among healthcare institutions, which may have an impact on the occurrence of central line-associated bloodstream infections (CLABSI). Nevertheless, there ...
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Article
Open AccessDecreased NK cell count is a high-risk factor for convulsion in children with COVID-19
The neurological symptoms caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are of increasing concern. Convulsions are among the main neurological manifestations reported in children with ...
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Article
Open AccessBiomarkers for isolated congenital heart disease based on maternal amniotic fluid metabolomics analysis
Congenital heart disease (CHD) is one of the most prevalent birth defects in the world. The pathogenesis of CHD is complex and unclear. With the development of metabolomics technology, variations in metabolite...
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Article
Open AccessGalcanezumab in episodic migraine: the phase 3, randomized, double-blind, placebo-controlled PERSIST study
Galcanezumab, a humanized monoclonal antibody that binds calcitonin gene-related peptide, has demonstrated efficacy and good tolerability in patients with episodic migraine in previous phase 3 trials. We repor...
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Article
Open AccessT2 relaxation time for the early prediction of treatment response to chemoradiation in locally advanced rectal cancer
Poor responders to chemoradiotherapy (CRT) for locally advanced rectal cancer (LARC) can still have a good prognosis if the treatment strategy is changed in time. However, no reliable predictor of early-treatm...
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Article
Open AccessGeographical disparities in infant mortality in the rural areas of China: a descriptive study, 2010–2018
The infant mortality rate (IMR) is considered a basic measure of public health for countries around the world. The specific aim of our study was to provide an updated description of infant mortality rate among...
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Article
Open AccessA systematic review of newborn and childhood hearing screening around the world: comparison and quality assessment of guidelines
This study aimed to assess the quality of global guidelines or consensus statements for newborn and childhood hearing screening, as well as to compare various guidelines between other countries and China.
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Article
Open AccessThe microbiological diagnostic performance of metagenomic next-generation sequencing in patients with sepsis
In this study, we aimed to perform a comprehensive analysis on the metagenomic next-generation sequencing for the etiological diagnosis of septic patients, and further to establish optimal read values for dete...
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Article
Open AccessSocial and environmental risk factors for unintentional suffocation among infants in China: a descriptive analysis
This retrospective study aimed to determine the epidemiological features of deaths caused by unintentional suffocation among infants in China.
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Article
Open AccessQuantitative evaluation of range and metabolic activity of hepatic alveolar echinococcosis lesion microenvironment using PET/CT and multi-site sampling method
Alveolar echinococcosis (AE) lesion microenvironment (LME) is crucial site where parasite-host interactions happen and of great significance during surgery and obtaining liver samples for basic research. Howev...
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Article
Open AccessClinicopathological characteristics of patients with paraproteinemia and renal damage
This study aimed to analyze the clinicopathological characteristics of patients with paraproteinemia and renal damage.
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Article
Open AccessNewborn hearing screening coverage and detection rates of hearing impairment across China from 2008-2016
Newborn hearing screening (NHS) can reduce the economic and social burden of hearing impairment. To track the progress of the goal set by the National Program of Action for Child Development (NPACD) and to est...
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Article
Open AccessResidual flow may increase the risk of adverse events in patients received combined catheter ablation and transcatheter left atrial appendage closure for nonvalvular atrial fibrillation: a meta-analysis
Catheter ablation (CA) and left atrial appendage closure (LAAC) have been combined into a novel one-stop procedure for patients with atrial fibrillation (AF). However, postoperative complications are relativel...
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Article
Open AccessClinical evaluation of haploidentical hematopoietic combined with human umbilical cord-derived mesenchymal stem cells in severe aplastic anemia
This study not only evaluated the clinical effects of treatment using haploidentical hematopoietic stem cells (haplo-HSCs) combined with human umbilical cord mesenchymal stem cells (UC-MSCs) in patients with s...
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Article
Open AccessEfficacy and safety of polymer-free stent versus polymer-permanent drug-eluting stent in patients with acute coronary syndrome: a meta-analysis of randomized control trials
The efficacy and safety of polymer-free stent (PFS) versus permanent polymer drug-eluting stent (PPDES) in patients undergoing percutaneous coronary intervention (PCI) remain controversial. Our meta-analysis w...
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Open AccessThe experiences of high school students with pulmonary tuberculosis in China: a qualitative study
Clustered tuberculosis (TB) still occurred nationally in Chinese schools every year, where high school students patients accounts for the highest proportion. These young TB patients are in a critical period of...