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Article
Graph neural news recommendation based on multi-view representation learning
Accurate news representation is of crucial importance in personalized news recommendation. Most of existing news recommendation model lack comprehensiveness because they do not consider the higher-order struct...
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Article
Open AccessThe maternal drug exposure birth cohort (DEBC) in China
Drug exposure during pregnancy lacks global fetal safety data. The maternal drug exposure birth cohort (DEBC) study, a prospective longitudinal investigation, aims to explore the correlation of maternal drug e...
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Article
Open AccessImpact of health literacy, social support, and socioeconomic position on the serum uric acid level in asymptomatic hyperuricaemia patients in China: a structural equation model
Hyperuricaemia (HUA) poses a significant public health challenge on a global scale. It is mostly asymptomatic hyperuricemia (AHU) with unsatisfactory recognition and control rates. The role of health literacy ...
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Article
High Temperature and High Pressure Sealing Performance Analysis and Optimization of Small Diameter Tubing Bridge Plug Rubber Tube
It is the key technology to reduce the pollution of production layer by using retrievable bridge plug to plug production string and carry out snubbing operation. This paper establishes the simulation calculati...
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Article
Open AccessLong non-coding RNA LINC00930 targeting miR-6792-3p/ZBTB16 regulates the proliferation and EMT of pancreatic cancer
Emerging evidence suggests the dysregulation of long non-coding RNAs (lncRNAs) involved in pancreatic cancer (PC). However, the function of LINC00930 in PC has not been elaborated. In this study, we found that...
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Article
Diversity and functional traits of seed endophytes of Dysphania ambrosioides from heavy metal contaminated and non-contaminated areas
Seed endophytes played a crucial role on host plants stress tolerance and heavy metal (HM) accumulation. Dysphania ambrosioides is a hyperaccumulator and showed strong tolerance and extraordinary accumulation cap...
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Article
Microbial infection promotes amyloid pathology in a mouse model of Alzheimer’s disease via modulating γ-secretase
Microbial infection as a type of environmental risk factors is considered to be associated with long-term increased risk of dementia, including Alzheimer’s disease (AD). AD is characterized by two neuropatholo...
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Article
The synthesis of CdS hierarchical micro-nanostructures with different pore structure and their influence on the photocatalytic ethanol transformation
Photocatalytic ethanol conversion into high-valuable chemicals while realizing hydrogen production is attractive and challenging. In this study, flower-like, porous flower-like, and net-like CdS nanostructures...
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Article
Open AccessChildhood migration experience and adult health: evidence from China’s rural migrants
Place of residence plays an influential role in sha** individual development, and studies have established links between Childhood migration experience (CME) and health outcomes through maturity. Over the pa...
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Article
Review and Comparative Analysis of Factor of Safety Definitions in Slope Stability
There are several definitions of the factor of safety used to quantitatively characterize slope or landslide stability, which can yield varying results. A comprehensive comparison of the differences among vari...
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Article
Open AccessOnion-like multicolor thermally activated delayed fluorescent carbon quantum dots for efficient electroluminescent light-emitting diodes
Carbon quantum dots are emerging as promising nanomaterials for next-generation displays. The elaborate structural design is crucial for achieving thermally activated delayed fluorescence, particularly for imp...
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Article
Open AccessSmall-molecule α-lipoic acid targets ELK1 to balance human neutrophil and erythrocyte differentiation
Erythroid and myeloid differentiation disorders are commonly occurred in leukemia. Given that the relationship between erythroid and myeloid lineages is still unclear. To find the co-regulators in erythroid an...
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Article
Open AccessEffect of Infusion Set Replacement Intervals on Central Line-Associated Bloodstream Infection in the Intensive Care Unit: Study Protocol of the INSPIRATION Study
The replacement intervals for infusion sets may differ among healthcare institutions, which may have an impact on the occurrence of central line-associated bloodstream infections (CLABSI). Nevertheless, there ...
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Article
Open AccessInterleukin-2 enhancer binding factor 2 negatively regulates the replication of duck hepatitis A virus type 1 by disrupting the RNA-dependent RNA polymerase activity of 3D polymerase
The interaction between viral components and cellular proteins plays a crucial role in viral replication. In a previous study, we showed that the 3′—untranslated region (3′—UTR) is an essential element for the...
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Article
Open AccessMesenchymal stem/stromal cells from human pluripotent stem cell-derived brain organoid enhance the ex vivo expansion and maintenance of hematopoietic stem/progenitor cells
Mesenchymal stem/stromal cells (MSCs) are of great therapeutic value due to their role in maintaining the function of hematopoietic stem/progenitor cells (HSPCs). MSCs derived from human pluripotent stem cells...
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Article
Open AccessAssociation of maternal phthalates exposure and metabolic gene polymorphisms with congenital heart diseases: a multicenter case-control study
The majority of congenital heart diseases (CHDs) are thought to result from the interactions of genetics and the environment factors. This study aimed to assess the association of maternal non-occupational pht...
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Article
Brain network centrality and connectivity are associated with clinical subtypes and disease progression in Parkinson’s disease
To investigate brain network centrality and connectivity alterations in different Parkinson’s disease (PD) clinical subtypes using resting-state functional magnetic resonance imaging (RS-fMRI), and to explore ...
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Article
Open AccessE3 ubiquitin ligase Herc3 deficiency leads to accumulation of subretinal microglia and retinal neurodegeneration
Activated microglia have been implicated in the pathogenesis of age-related macular degeneration (AMD), diabetic retinopathy, and other neurodegenerative and neuroinflammatory disorders, but our understanding ...
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Article
Open AccessTGN-020 Alleviate Inflammation and Apoptosis After Cerebral Ischemia–Reperfusion Injury in Mice Through Glymphatic and ERK1/2 Signaling Pathway
Post-stroke acute inhibition of aquaporin 4 (AQP4) is known to exacerbate inflammation and apoptosis, yet the underlying mechanisms are not fully understood. The objective of this study was to investigate the ...
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Article
Adaptation of Glucose Metabolism to Limb Autotomy and Regeneration in the Chinese Mitten Crab
Limb autotomy and regeneration represent distinctive responses of crustaceans to environmental stress. Glucose metabolism plays a pivotal role in energy generation for tissue development and regeneration acros...
