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Article
Research on Structural Defect Characteristics and Influencing Factors for High-Fill Cut-and-Cover Tunnels in Mountainous Areas
In regions such as Chongqing where high-fill areas are prevalently distributed, cut-and-cover tunnels traversing such terrains are subjected to considerable structural risks due to unconsolidated or unstable h...
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Article
A Modified Jacking Force Model to Predict Sliding Friction Coefficient Considering Partially Developed Arching Effect in Highly Weathered Rocks
Here, the prediction of friction characteristics for pipe jacking drives during soil traversing has been explored. This work is done in the context of no great understanding of how drivers negotiate highly wea...
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Article
Optimizing stability design of support system for the parallel tunnels excavation crossing a fill slope
Tunnel construction is becoming necessary as cities continue to grow, particularly in crowded locations. Thus, the majority of tunneling projects include creating two parallel tunnels, which known as twin tunn...
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Article
Quantitative trait loci detection for three tiller-related traits and the effects on wheat (Triticum aestivum L.) yields
A total of 38 putative additive QTLs and 55 pairwise putative epistatic QTLs for tiller-related traits were reported, and the candidate genes underlying qMtn-KJ-5D, a novel major and stable QTL for maximum tiller...
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Article
Study on Spatiotemporal Evolution Laws and Deformation Characteristics of Circular Deep and Large Foundation Pits in Soft Soils
With the increasing demand for large and deep anchor projects in soft soil areas, issues related to settlement in circular foundation pits and damage to supporting structures have become significantly pronounc...
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Article
Open AccessGSTM3 enhances radiosensitivity of nasopharyngeal carcinoma by promoting radiation-induced ferroptosis through USP14/FASN axis and GPX4
Radiotherapy is a critical treatment modality for nasopharyngeal carcinoma (NPC). However, the mechanisms underlying radiation resistance and tumour recurrence in NPC remain incompletely understood.
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Chapter and Conference Paper
Time-Warp-Invariant Processing with Multi-spike Learning
Sensory signals are encoded and processed by neurons in the brain in a form of action potentials, also called spikes that carry clue information across both spatial and temporal dimensions. Learning of such a ...
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Article
Association between host nitrogen absorption and root-associated microbial community in field-grown wheat
Plant roots and rhizosphere soils assemble diverse microbial communities, and these root-associated microbiomes profoundly influence host development. Modern wheat has given rise to numerous cultivars for its ...
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Article
Open AccessLeveraging circulating microbiome signatures to predict tumor immune microenvironment and prognosis of patients with non-small cell lung cancer
Accumulating evidence supports the significant role of human microbiome in development and therapeutic response of tumors. Circulating microbial DNA is non-invasive and could show a general view of the microbi...
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Article
Settlement characteristics due to excavate twin tunnels in a supported slope: model test and numerical simulation
Traffic issues are a result of rising population, expanding urbanization, and rising living standards. Consequently, there is a growing demand for the urban rail and road transport network to evolve. Twin tunn...
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Article
The spatiotemporal impact of urban elderly care facilities on residential value and the resulting governance implications
As the world is increasingly witnessing an aging society, the demand for elderly care facilities has gradually increased. However, there is controversy regarding the impact of 'establishing elderly care facili...
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Article
QTL Detection for Internode Component Index in Wheat Using a RIL Map** Population
Plant height (PH) is one of the most important traits related to plant architecture in wheat. Together, the lengths of individual internodes determine plant height and have a great influence on lodging resista...
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Article
The Effects of Interface Roughness on the Pull-Out Performance and Failure Characteristics of Tunnel-Type Anchorages in Soft Rock
To investigate the effects of interface roughness on the pull-out performance and stability of a tunnel-type anchorage (TTA) installed in soft rock, tensile load tests are performed with model plug bodies with...
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Article
Liposome-coated CaO2 nanoblockers for enhanced checkpoint blockade therapy by inhibiting PD-L1 de novo biosynthesis
The blocking of the immune checkpoint pathway with antibodies, especially targeting to programmed death-1/programmed death ligand-1 (PD-1/PD-L1) pathway, was currently a widely used treatment strategy in clini...
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Article
Open AccessLow-carbon city planning based on collaborative analysis of supply and demand scenarios
With the proposal of carbon reduction goals of countries around the world, "green and low-carbon" has become a new key to urban development and construction. However, in the existing urban planning system, the...
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Article
Thoracic interstitial injection of drug-liposomes in mice for treating atherosclerosis
Intervaginal space injection (ISI) is a novel mode of administration investigated over the last decade. After injecting nanoparticles into the intervaginal space, they can be transported along low flow resista...
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Article
Settlement Characteristic Due to Excavate Parallel Tunnels in a Fill-rock Slope: Model Test and Numerical Analysis
The settlement caused by excavating twin tunnels on a slope is regarded as a critical aspect in assuring asymmetric twin tunnel safety. In this paper, both physical model test and numerical analysis (FEM) were...
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Article
Investigation on the dynamic cumulative damage mechanism and stability of bedding rock slope under the deterioration of rock mass in the hydro-fluctuation belt
The deterioration of rock mass in the hydro-fluctuation belt and reservoir-induced earthquakes in the Three Gorges Reservoir Area (TGRA) have great impact on the stability of bedding rock slope. The cumulative...
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Article
Identification of a major stable QTL for spikelet number in wheat (Triticum aestivum L.) and its genetic effects analysis on yield-related traits
As one of the important spike components, spikelet number is closely related to wheat yield. In the present study, a major stable QTL for spikelet number per spike (SNPS), qSnps-7D, was identified using a recombi...
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Article
Open AccessMicrobial hydrogen “manufactory” for enhanced gas therapy and self-activated immunotherapy via reduced immune escape
As an antioxidant, hydrogen (H2) can selectively react with the highly toxic hydroxyl radical (·OH) in tumor cells to break the balance of reactive oxygen species (ROS) and cause oxidative stress. However, due to...
