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  1. No Access

    Article

    Associations of insulin sensitivity and immune inflammatory responses with child blood lead (Pb) and PM2.5 exposure at an e-waste recycling area during the COVID-19 lockdown

    Fine particular matter (PM2.5) and lead (Pb) exposure can induce insulin resistance, elevating the likelihood of diabetes onset. Nonetheless, the underlying mechanism remains ambiguous. Consequently, we assessed ...

    **angbin Zheng, Qihua Wang, **** Xu in Environmental Geochemistry and Health (2024)

  2. Article

    Open Access

    Inaccurate diagnosis of diabetes type in youth: prevalence, characteristics, and implications

    Classifying diabetes at diagnosis is crucial for disease management but increasingly difficult due to overlaps in characteristics between the commonly encountered diabetes types. We evaluated the prevalence an...

    Mustafa Tosur, **aofan Huang, Audrey S. Inglis in Scientific Reports (2024)

  3. No Access

    Chapter and Conference Paper

    Local Maximum Synchrosqueezing-Based Velocity Synchronous Chirplet Transform for Bearing Multi-Fault Diagnosis

    The chirplet transform is widely used to process nonstationary signals and detect mechanical faults. Recently, the velocity synchronous linear chirplet transform (VSLCT), can effectively alleviate the smear ef...

    Dezun Zhao, Honghao Wang, **aofan Huang in Proceedings of the UNIfied Conference of D… (2024)

  4. No Access

    Article

    Characterization and stabilization of incineration fly ash from a new multi-source hazardous waste co-disposal system: field-scale study on solidification and stabilization

    The multi-source hazardous waste co-disposal system, a recent innovation in the industry, offers an efficient approach for hazardous waste disposal. The incineration fly ash (HFA) produced by this system exhib...

    **aofan Huang, Lei Wang, Gu Fan, **aotao Bi in Environmental Science and Pollution Resear… (2024)

  5. Article

    Open Access

    A generalizable and interpretable model for mortality risk stratification of sepsis patients in intensive care unit

    This study aimed to construct a mortality model for the risk stratification of intensive care unit (ICU) patients with sepsis by applying a machine learning algorithm.

    **hu Zhuang, Haofan Huang, Song Jiang in BMC Medical Informatics and Decision Making (2023)

  6. No Access

    Article

    A retrospective study of air quality associated with teratogenic pathogen screening in women of reproductive age in southern China

    Adverse pregnancy outcomes are associated with a poor ambient atmospheric environment. Infections by teratogenic pathogens such as cytomegalovirus (CMV) and herpes simplex virus (HSV) are the main cause of the...

    Yanrong Chen, **angbin Zheng, **aofan Huang in Environmental Science and Pollution Resear… (2023)

  7. Article

    Open Access

    AGGF1 therapy inhibits thoracic aortic aneurysms by enhancing integrin α7-mediated inhibition of TGF-β1 maturation and ERK1/2 signaling

    Thoracic aortic aneurysm (TAA) is a localized or diffuse dilatation of the thoracic aortas, and causes many sudden deaths each year worldwide. However, there is no effective pharmacologic therapy. Here, we sho...

    **ngwen Da, Ziyan Li, **aofan Huang, Zuhan He, Yubing Yu in Nature Communications (2023)

  8. No Access

    Chapter and Conference Paper

    Identification of Sepsis Subphenotypes Based on Bi-directional Long Short-Term Memory Auto-encoder Using Real-Time Laboratory Data Collected from Intensive Care Units

    Sepsis is a heterogeneous syndrome characterized by a dysregulated immunological response to infection that results in organ dysfunction and often death. Identification of clinically relevant subphenotypes, wh...

    Yongsen Tan, Jiahui Huang, **hu Zhuang, Haofan Huang in Health Information Processing (2023)

  9. No Access

    Chapter and Conference Paper

    Investigation on Steady State Characteristics and Loss Reduction Measures of 220 kV Power Cables

    With the rapid development of urbanization in China, power cables have gradually occupied the main position in the urban network, and the loss caused by the power cables in the power transmission has also cont...

    Ligang Zhang, Lifeng Qui, Enzhe Wang in The 37th Annual Conference on Power System… (2023)

  10. No Access

    Article

    Liquid crystal-based optical aptasensor for the sensitive and selective detection of Gram-negative bacteria

    The sensitive and differential detection of Gram-negative bacteria is essential in food processing, environmental monitoring, and the daily chemical industry. Herein, we propose and validate a liquid crystal (...

    Mengjun Liu, Minmin Zhang, Jiamei Chen, Ruizhi Yang in Science China Chemistry (2022)

  11. Article

    Open Access

    Open-source algorithm and software for computed tomography-based virtual pancreatoscopy and other applications

    Pancreatoscopy plays a significant role in the diagnosis and treatment of pancreatic diseases. However, the risk of pancreatoscopy is remarkably greater than that of other endoscopic procedures, such as gastro...

    Haofan Huang, **axia Yu, Mu Tian, Weizhen He in Visual Computing for Industry, Biomedicine… (2022)

  12. No Access

    Article

    Enhancement of electrical properties by including nano-aluminum nitride to micro-silicon carbide/silicone elastomer composites for potential power module packaging applications

    This paper reports an enhancement of the electrical properties of micro-silicon carbide/silicone elastomer (m-SiC/SE) composites by adding nano-aluminum nitride (n-AlN) for the next-generation power module enc...

    **angrong Chen, Qilong Wang, **aofan Huang in Journal of Materials Science: Materials in… (2022)

  13. Article

    Impact of the COVID-19 pandemic on visual outcomes of diabetic macular edema patients at a tertiary care veterans affairs center

    There are limited studies on factors that impacted retina clinic patient outcomes during the COVID-19 pandemic. We aimed to evaluate visual and anatomic outcomes in patients with diabetic macular edema (DME) r...

    Philip Zhou, Jie Gao, **aofan Huang in Journal of Diabetes & Metabolic Disorders (2022)

  14. Article

    Open Access

    Predictors and outcomes of postoperative tracheostomy in patients undergoing acute type A aortic dissection surgery

    Despite surgical advances, acute type A aortic dissection remains a life-threatening disease with high mortality and morbidity. Tracheostomy is usually used for patients who need prolonged mechanical ventilati...

    Dashuai Wang, Su Wang, Yu Song, Hongfei Wang, Anchen Zhang in BMC Cardiovascular Disorders (2022)

  15. Article

    Open Access

    Development and validation of a risk prediction model for postoperative pneumonia in adult patients undergoing Stanford type A acute aortic dissection surgery: a case control study

    Pneumonia is a common complication after Stanford type A acute aortic dissection surgery (AADS) and contributes significantly to morbidity, mortality, and length of stay. The purpose of this study was to ident...

    Dashuai Wang, **aerzhati Abuduaini, **aofan Huang in Journal of Cardiothoracic Surgery (2022)

  16. No Access

    Article

    Bayesian optimization of functional output in inverse problems

    Motivated by the parameter identification problem of a reaction-diffusion transport model in a vapor phase infiltration processes, we propose a Bayesian optimization procedure for solving the inverse problem t...

    Chaofan Huang, Yi Ren, Emily K. McGuinness, Mark D. Losego in Optimization and Engineering (2021)

  17. No Access

    Article

    Constrained minimum energy designs

    Space-filling designs are important in computer experiments, which are critical for building a cheap surrogate model that adequately approximates an expensive computer code. Many design construction techniques...

    Chaofan Huang, V. Roshan Joseph, Douglas M. Ray in Statistics and Computing (2021)

  18. Article

    Open Access

    Risk factors and in-hospital mortality of postoperative hyperlactatemia in patients after acute type A aortic dissection surgery

    Hyperlactatemia may be caused by increased production due to tissue hypoxia or non-hypoxia. The aim of this study was first to identify risk factors for postoperative hyperlactatemia (POHL) after Stanford type...

    Su Wang, Dashuai Wang, **aofan Huang, Hongfei Wang in BMC Cardiovascular Disorders (2021)

  19. No Access

    Article

    Tetrasubstituted allenes via the palladium-catalysed kinetic resolution of propargylic alcohols using a supporting ligand

    Efficient enantioselective construction of fully substituted allenes from simple starting materials is still a fundamental challenge due to the difficulty to discriminate between the four substituents at the 1...

    Wei-Feng Zheng, Wanli Zhang, Chaofan Huang, Penglin Wu, Hui Qian in Nature Catalysis (2019)

  20. Article

    Open Access

    Inhibition of intimal hyperplasia in murine aortic allografts by administration of a small-molecule TLR4 inhibitor TAK-242

    Graft arteriosclerosis (GA) is the leading cause of late cardiac allograft dysfunction. The innate immune system plays a major role in GA, paprticularly Toll-like receptor 4 (TLR4) signaling. Here we character...

    Chuangyan Wu, **angchao Ding, Cheng Zhou, ** Ye, Yuan Sun, Jie Wu in Scientific Reports (2017)

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