5 Result(s)
within
**aochuan Chen
Biomedicine
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Article
Open AccessIdentification of novel molecular subtypes to improve the classification framework of nasopharyngeal carcinoma
Nasopharyngeal carcinoma (NPC) treatment is largely based on a ‘one-drug-fits-all’ strategy in patients with similar pathological characteristics. However, given its biological heterogeneity, patients at the s...
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Article
Open AccessIntegrated multi-omics analyses reveal Jorunnamycin A as a novel suppressor for muscle-invasive bladder cancer by targeting FASN and TOP1
Bladder cancer is a urological carcinoma with high incidence, among which muscle invasive bladder cancer (MIBC) is a malignant carcinoma with high mortality. There is an urgent need to develop new drugs with l...
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Article
Open AccessBioinformatics analysis combined with experiments predicts CENPK as a potential prognostic factor for lung adenocarcinoma
Lung cancer is the most common malignant tumor. Identification of novel diagnostic and prognostic biomarkers for lung cancer is a key research imperative. The role of centromere protein K (CENPK) in cancer is ...
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Article
Mycoplasma-mediated alterations of in vitro generation and functions of human dendritic cells
While tumor cell-derived factors have been demonstrated to hamper the in vitro differentiation and maturation of dendritic cells (DCs) from hematopoietic stem cells, their effects on DC differentiation from CD14+
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Article
Open AccessAlteration of T cell immunity by lentiviral transduction of human monocyte-derived dendritic cells
Dendritic cells (DCs) are professional antigen-presenting cells that play important roles during human immunodeficiency virus type 1 (HIV-1) infection. HIV-1 derived lentiviral vectors (LVs) transduce DCs at h...
