8 Result(s)

Article

C/EBPαp30 plays transcriptional regulatory roles distinct from C/EBPαp42

CCAAT/enhancer binding protein α (C/EBPα) is a transcriptional regulatory factor that inhibits cell proliferation, and alternative translational initiation produces two polypeptides, C/EBPαp30 and C/EBPαp42. B...

Chunxi Wang, **aotao Chen, Yan** Wang, Jialei Gong, Gengxi Hu in Cell Research (2007)

Article

Enhanced efficiency of generating induced pluripotent stem (iPS) cells from human somatic cells by a combination of six transcription factors

**g Liao, Zhao Wu, Ying Wang, Lu Cheng, Chun Cui, Yuan Gao, Taotao Chen… in Cell Research (2008)

Article

Yamanaka factors critically regulate the developmental signaling network in mouse embryonic stem cells

Yamanaka factors (Oct3/4, Sox2, Klf4, c-Myc) are highly expressed in embryonic stem (ES) cells, and their over-expression can induce pluripotency in both mouse and human somatic cells, indicating that these fa...

**aosong Liu, **yan Huang, Taotao Chen, Ying Wang, Shunmei **n, Jian Li… in Cell Research (2008)

Article

More synergetic cooperation of Yamanaka factors in induced pluripotent stem cells than in embryonic stem cells

The role of Yamanaka factors as the core regulators in the induction of pluripotency during somatic cell reprogramming has been discovered recently. Our previous study found that Yamanaka factors regulate a de...

**yan Huang, Taotao Chen, **aosong Liu, **g Jiang, **song Li… in Cell Research (2009)

Article

Ascorbic acid enhances the cardiac differentiation of induced pluripotent stem cells through promoting the proliferation of cardiac progenitor cells

Generation of induced pluripotent stem cells (iPSCs) has opened new avenues for the investigation of heart diseases, drug screening and potential autologous cardiac regeneration. However, their application is ...

Nan Cao, Zumei Liu, Zhongyan Chen, Jia Wang, Taotao Chen, **aoyang Zhao… in Cell Research (2012)

Article

Erratum: Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivin

Nat. Cell Biol. 14, 1203–1211 (2012); published online 7th October 2012; corrected online 14 March 2013 During the preparation of Fig. 8c, the image of c-Fos staining on non-HCC samples was inadvertantly dupli...

Lihua Min, Yuan Ji, Latifa Bakiri, Zhixin Qiu, ** Cen, **aotao Chen… in Nature Cell Biology (2013)