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Article
Propagation of the Longitude Stress Wave through a Filled Fracture Considering Cyclic Loading/Unloading Behaviours
Modelling the response of the filled fracture to the stress wave is of great significance for the prediction and prevention of rock mass instability under dynamic loads. An actual stress wave has varied freque...
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Article
Ultrasensitive dynamic light scattering immunodetection of alpha-fetoprotein using heptamer-amplified nanoparticle crosslinking aggregation
A novel construction strategy is introduced for an ultrasensitive dynamic light scattering (DLS) immunosensor targeting alpha fetoprotein (AFP). This approach relies on a self-assembled heptamer fusion protei...
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Article
Open AccessPPIH acts as a potential predictive biomarker for patients with common solid tumors
Our previous studies have indicated that mRNA and protein levels of PPIH are significantly upregulated in Hepatocellular Carcinoma (LIHC) and could act as predictive biomarkers for patients with LIHC. Nonetheless...
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Article
Identification and Thermostability Modification of the Mesophilic L-asparaginase from Limosilactobacillus secaliphilus
L-asparaginase (L-ASNase, E.C.3.5.1.1) could effectively inhibit the formation of acrylamide (AA) by hydrolyzing the AA precursor L-asparagine. However, most of the L-ASNases showed a relatively weak thermosta...
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Article
Measurement of Elastic Bi-modulus of Rock-type Materials: Insight from comparative and parallel tests
Rock materials exhibit different elastic moduli under tension and compression, making them typical bi-modulus materials. Few testing methods can measure both tensile and compressive moduli (Et and Ec) of such mat...
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Article
Open AccessMulti-cohort study on cytokine and chemokine profiles in the progression of COVID-19
Various substances in the blood plasma serve as prognostic indicators of the progression of COVID-19. Consequently, multi-omics studies, such as proteomic and metabolomics, are ongoing to identify accurate bio...
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Article
Open AccessFGF7 enhances the expression of ACE2 in human islet organoids aggravating SARS-CoV-2 infection
The angiotensin-converting enzyme 2 (ACE2) is a primary cell surface viral binding receptor for SARS-CoV-2, so finding new regulatory molecules to modulate ACE2 expression levels is a promising strategy agains...
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Article
Compression-Hardening Memory of the Microstructure and Its Effect on the Cyclic Loading/Unloading Response of Crystalline Rock Using a Grain-Based Model
A rock can undergo hardening deformation during compression and have a memory of the hardening action, which can be displayed when unloaded. This compression-hardening memory effect (CHME) is related to the mi...
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Article
Open AccessDendritic mGluR2 and perisomatic Kv3 signaling regulate dendritic computation of mouse starburst amacrine cells
Dendritic mechanisms driving input-output transformation in starburst amacrine cells (SACs) are not fully understood. Here, we combine two-photon subcellular voltage and calcium imaging and electrophysiologica...
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Chapter and Conference Paper
DeCAB: Debiased Semi-supervised Learning for Imbalanced Open-Set Data
Semi-supervised learning (SSL) has received significant attention due to its ability to use limited labeled data and various unlabeled data to train models with high generalization performance. However, the as...
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Article
Open AccessThe effects of preconceptions on directed forgetting - the example of e-learning
This study used the item-based legal forgetting paradigm to investigate the effects of preconception type and material type on directed forgetting, and further explored the effects of preconception on directed...
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Article
Open AccessAssociation between serum lipoprotein(a) and mildly reduced eGFR: a cross-sectional study
Lipoprotein(a) [Lp(a)] is a risk factor for cardiovascular disease (CVD) and aortic stenosis. However, the data on the relationship between Lp(a) and mildly reduced estimated glomerular filtration rate (eGFR) ...
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Article
The impacts of driving variables on energy-related carbon emissions reduction in the building sector based on an extended LMDI model: a case study in China
As China’s main contributor to energy-related carbon emissions, the building sector in Jiangsu Province generates around 13.58% of the national carbon emissions. However, the influential variables of the energ...
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Article
Urban–rural interface dominates the effects of urbanization on watershed energy and water balances in Southern China
Quantifying the interactions between land disturbances and energy and water balances, particularly evapotranspiration (ET), is helpful for understanding the land-atmospheric interactions and assessing the effe...
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Article
Open AccessImmunity-and-matrix-regulatory cells enhance cartilage regeneration for meniscus injuries: a phase I dose-escalation trial
Immunity-and-matrix-regulatory cells (IMRCs) derived from human embryonic stem cells have unique abilities in modulating immunity and regulating the extracellular matrix, which could be mass-produced with stab...
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Article
Early age at menarche is associated with an increased risk of preeclampsia and adverse neonatal outcomes: a 6‑year retrospective study
Preeclampsia affects between 2 to 8% of pregnancies worldwide and is associated with significant adverse outcomes for both mothers and their offspring. The present study aims to investigate whether there is a ...
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Article
Open AccessUrbanization alters atmospheric dryness through land evapotranspiration
‘Urban Dry (Wet) Islands’ (UDI/UWI) represents microclimate change that impacts ecosystems and human well-being. However, causes of the UDI (UWI) phenomena are not fully understood due to the lack of empirical...
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Article
Synergistic effect of rainfall and pipe leakage erosion on the formation and development of loess caves in Weinan city, Loess Plateau, Northwest China
Rapid urban expansion and climate change often bring about loess cave disasters on the Chinese Loess Plateau. It is believed that human activity and rainfall can synergistically alter the hydrogeological condi...
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Article
Weighted neural tangent kernel: a generalized and improved network-induced kernel
The neural tangent kernel (NTK) has recently attracted intense study, as it describes the evolution of an over-parameterized neural network (NN) trained by gradient descent. However, it is now well-known that ...
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Article
Improving Colonoscopy Polyp Detection Rate Using Semi-Supervised Learning
Colorectal cancer is one of the biggest health threats to humans and takes thousands of lives every year. Colonoscopy is the gold standard in clinical practice to inspect the intestinal wall, detect polyps and...
