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Open AccessPublisher Correction: Mechanisms underlying the interactions and adaptability of nitrogen removal microorganisms in freshwater sediments
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Open AccessMechanisms underlying the interactions and adaptability of nitrogen removal microorganisms in freshwater sediments
Microorganisms in eutrophic water play a vital role in nitrogen (N) removal, which contributes significantly to the nutrient cycling and sustainability of eutrophic ecosystems. However, the mechanisms underlyi...
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Open AccessHypofractionated radiotherapy with simultaneous tumor bed boost (Hi-RISE) in breast cancer patients receiving upfront breast-conserving surgery: study protocol for a phase III randomized controlled trial
The effectiveness and safety of moderately hypofractionated radiotherapy (HFRT) in patients undergoing breast-conserving surgery (BCS) has been demonstrated in several pivotal randomized trials. However, the f...
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Open AccessCorrection: The association between hemoglobin level and sarcopenia in Chinese patients with Crohn’s disease
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Phantom study of a self-shielded X-ray bone age assessment instrument against scattered radiation in children
Hand-wrist radiography is the most common and accurate method for evaluating children’s bone age. To reduce the scattered radiation of radiosensitive organs in bone age assessment, we designed a small X-ray in...
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Open AccessInterleukin-2 enhancer binding factor 2 negatively regulates the replication of duck hepatitis A virus type 1 by disrupting the RNA-dependent RNA polymerase activity of 3D polymerase
The interaction between viral components and cellular proteins plays a crucial role in viral replication. In a previous study, we showed that the 3′—untranslated region (3′—UTR) is an essential element for the...
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Open AccessCorrection: The association between hemoglobin level and sarcopenia in Chinese patients with Crohn’s disease
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Open AccessThe association between hemoglobin level and sarcopenia in Chinese patients with Crohn’s disease
Sarcopenia and anemia are common complications in patients with Crohn’s Disease (CD). However, few studies have shown the association between sarcopenia and hemoglobin levels in CD patients. This retrospective...
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Corneal endothelial morphology changes in patients with proliferative diabetic retinopathy
Diabetes patients often suffer from diabetes keratopathy in the course of their illness. The examination of corneal endothelium in proliferative diabetic retinopathy (PDR) patients has important clinical signi...
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Open AccessAdjuvant medial versus entire supraclavicular lymph node irradiation in high-risk early breast cancer (SUCLANODE): a protocol for a multicenter, randomized, open-label, phase 3 trial
Supraclavicular nodal (SCL) irradiation is commonly used for patients with high-risk breast cancer after breast surgery. The Radiation Therapy Oncology Group (RTOG) and European Society for Radiotherapy and On...
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The elusive nature of the oligoclonal bands in multiple sclerosis
Intrathecal immunoglobulin G (IgG) and oligoclonal bands (OCBs) detected in both the brain and cerebrospinal fluid (CSF) are seminal features of multiple sclerosis (MS). The presence of OCBs correlates with el...
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Open AccessEffects of climate warming and human activities on the distribution patterns of Fritillaria unibracteata in eastern Qinghai-Tibetan Plateau
Fritillaria unibracteata is an endangered medicinal material species endemic to the Qinghai Tibet Plateau, and belongs to the national Class III endangered plant. In addition to expelling wind and removing damne,...
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Open AccessR-loop-dependent promoter-proximal termination ensures genome stability
The proper regulation of transcription is essential for maintaining genome integrity and executing other downstream cellular functions1,2. Here we identify a stable association between the genome-stability regula...
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Open AccessRoles of follicle stimulating hormone and sphingosine 1-phosphate co-administered in the process in mouse ovarian vitrification and transplantation
Some major challenges of ovarian tissue vitrification and transplantation include follicle apoptosis induced by cryopreservation and ischemia-reperfusion injury, as well as ovarian follicle loss during post-tr...
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Open AccessFavorable prognosis of breast cancer brain metastases patients with limited intracranial and extracranial metastatic lesions
Breast cancer brain metastases (BCBM) are highly heterogenous with widely differing survival. The prognosis of the oligometastatic breast cancer (BC) patients with brain metastases (BM) has not been well studi...
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Ecotoxicological risk assessment of 14 pesticides and corresponding metabolites to groundwater and soil organisms using China-PEARL model and RQ approach
Global use of pesticides brings uncertain risks to human and nontarget species via environmental matrix. Currently, various models for exposure risk assessment are developed and widely used to forecast the imp...
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Open AccessMetformin promotes female germline stem cell proliferation by upregulating Gata-binding protein 2 with histone β-hydroxybutyrylation
Metformin as a first-line clinical anti-diabetic agent prolongs the lifespan of model animals and promotes cell proliferation. However, the molecular mechanisms underlying the proliferative phenotype, especial...
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Open AccessOocyte Arrested at Metaphase II Stage were Derived from Human Pluripotent Stem Cells in vitro
Initiation of meiosis is the most difficult aspect of inducing competent oocytes differentiation from human stem cells in vitro. Human induced pluripotent stem cells (hiPSCs) and embryonic stem cells (hESCs) were...
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Open AccessMultiple sclerosis plasma IgG aggregates induce complement-dependent neuronal apoptosis
Grey matter pathology is central to the progression of multiple sclerosis (MS). We discovered that MS plasma immunoglobulin G (IgG) antibodies, mainly IgG1, form large aggregates (>100 nm) which are retained i...
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Open AccessVertically stratified methane, nitrogen and sulphur cycling and coupling mechanisms in mangrove sediment microbiomes
Mangrove ecosystems are considered as hot spots of biogeochemical cycling, yet the diversity, function and coupling mechanism of microbially driven biogeochemical cycling along the sediment depth of mangrove w...
