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    Article

    Development of a real-time multiplex PCR assay for detection of viral pathogens of penaeid shrimp

    A real-time multiplex polymerase chain reaction (rtm-PCR) assay was developed and optimized to simultaneously detect three viral pathogens of shrimp in one reaction. Three sets of specific oligonucleotide prim...

    Zhixun **e, Liji **e, Yaoshan Pang, Zhaofa Lu, Zhiqin **e in Archives of Virology (2008)

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    Inefficiency of C3H/HeN Mice to Control Chlamydial Lung Infection Correlates with Downregulation of Neutrophil Activation During the Late Stage of Infection

    We previously reported that massive infiltration of neutrophils in C3H/HeN (C3H) mice could not efficiently control Chlamydia muridarum (Cm) infection and might contribute to the high susceptibility of these mice...

    **aofei Tang, **aokun Bu, Naihong Zhang, **aoxia Li in Cellular & Molecular Immunology (2009)

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    Article

    Type 1 T-cell responses in chlamydial lung infections are associated with local MIP-1α response

    Chemokines and their receptors are important mediators of leukocyte trafficking and recruitment and sometimes work as modulators of T-cell responses during infections and inflammation. Modulating the biologica...

    Naihong Zhang, Zhaoe Wang, **aofei Tang, Hai** Wang in Cellular & Molecular Immunology (2010)

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    A pH/Time/Pectinase-Dependent Oral Colon-Targeted System Containing Isoliquiritigenin: Pharmacokinetics and Colon Targeting Evaluation in Mice

    Oral colon-targeted gel beads containing isoliquiritigenin (ISL) were successfully designed in our study. In order to further explore the targeting of the colon by the gel beads, a systematic study of their in...

    **aoFei Tang, **aoYun Zhang, QianQian Zhao in European Journal of Drug Metabolism and Ph… (2022)

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    Article

    Transdermal Delivery of Estradiol Simultaneously Possessing Rapid Release and Sustained Release Effect

    Dissolving microneedle (DMN) has been researched as a drug delivery technology that improves drug molecule transportation through the skin with little discomfort. However, the sluggish drug absorption, poor sk...

    **aoFei Tang, Huaiying Qin, Jianhua Yang, **aoYun Zhang in AAPS PharmSciTech (2023)

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    Article

    Design, optimization, and evaluation for a long-time-released transdermal microneedle delivery system containing estradiol

    Transdermal drug delivery systems (TDDS) have drawbacks such as poor absorption, low blood concentration, and delayed effects. Dissolving microneedle has sharp tips and short length, which overcome patients’ p...

    **aoFei Tang, Huaiying Qin, **aoYun Zhang in Drug Delivery and Translational Research (2024)