1,713 Result(s)
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**ao-yu Wang
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Article
Open AccessMining the interpretable prognostic features from pathological image of intrahepatic cholangiocarcinoma using multi-modal deep learning
The advances in deep learning-based pathological image analysis have invoked tremendous insights into cancer prognostication. Still, lack of interpretability remains a significant barrier to clinical application.
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Constructing 2D bismuth-based heterostructure for highly efficient photocatalytic CO2 reduction
Reforming carbon dioxide (CO2) into fuels and valuable chemicals using solar energy holds significant potential for emission reduction and addressing energy supply challenges. The recombination of photocarriers r...
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Distribution, risk evaluation, and source allocation of cesium and strontium in surface soil in a mining city
Radioactive nuclides cesium (Cs) and strontium (Sr) possess long half-lives, with 135Cs at approximately 2.3 million years and 87Sr at about 49 billion years. Their persistent accumulation can result in long-last...
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Characterization of a pangolin SARS-CoV-2-related virus isolate that uses the human ACE2 receptor
Various SARS-CoV-2-related coronaviruses have been increasingly identified in pangolins, showing a potential threat to humans. Here we report the infectivity and pathogenicity of the SARS-CoV-2-related virus, ...
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Acetylcytidine modification of Amotl1 by N-acetyltransferase 10 contributes to cardiac fibrotic expansion in mice after myocardial infarction
Cardiac fibrosis is a pathological scarring process that impairs cardiac function. N-acetyltransferase 10 (Nat10) is recently identified as the key enzyme for the N4-acetylcytidine (ac4C) modification of mRNAs...
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Open AccessA Phase 3, Randomized, Controlled Trial Evaluating the Efficacy and Safety of Ropeginterferon Alfa-2b in Patients with Moderate COVID-19
Ropeginterferon alfa-2b is a novel mono-pegylated proline-interferon. This clinical study aimed to evaluate its antiviral efficacy of ropeginterferon alfa-2b against SARS-CoV-2 infection.
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Conditional Survival of Patients with Limited-Stage Small Cell Lung Cancer After Surgery: A National Real-World Cohort Study
The prognosis of limited-stage small cell lung cancer (LS-SCLC) after surgery usually is estimated at diagnosis, but how the prognosis actually evolves over time for patients who survived for a predefined time...
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Article
Progress and challenges of electrolyte modulation in aqueous zinc-ion batteries
As a new type of green battery system, aqueous zinc-ion batteries (AZIBs) have gradually become a research hotspot due to their low cost, high safety, excellent stability, high theoretical capacity (820 mAh·g−1) ...
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Improvement in corrosion resistance of Mg97Zn1Y2 alloy by Zr addition
Magnesium alloys, known for their exceptional lightweight properties, have presented challenges in various applications due to their limited corrosion resistance. In this study, the corrosion resistance of Mg97Zn
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Simplified p-i-n Perovskite Solar Cells with a Multifunctional Polyfullerene Electron Transporter
In prevailing p-i-n perovskite solar cells (PSCs), solution-processible fullerene molecules are widely used as electron-transporting layers (ETLs) but they typically suffer from poor uniformity and undesirable...
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Article
Low cost and low density chloride solid electrolyte for all solid state cathode with high active material ratio
Chloride solid electrolytes (SEs) have attracted widespread attention due to their high room-temperature ionic conductivity and excellent cathode compatibility. However, the conventionally selected central met...
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Article
Open AccessN6-methyladenosine modified TGFB2 triggers lipid metabolism reprogramming to confer pancreatic ductal adenocarcinoma gemcitabine resistance
Gemcitabine resistance is a major obstacle to the effectiveness of chemotherapy in pancreatic ductal adenocarcinoma (PDAC). Therefore, new strategies are needed to sensitize cancer cells to gemcitabine. Here, ...
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Article
Lethal pulmonary thromboembolism in mice induced by intravenous human umbilical cord mesenchymal stem cell-derived large extracellular vesicles in a dose- and tissue factor-dependent manner
Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) have obvious advantages over MSC therapy. But the strong procoagulant properties of MSC-EVs pose a potential risk of thromboembolism, an issue tha...
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Article
Two new aromatic tenvermectins from mutant Streptomyces avermitilis HU02-06
Two new aromatic tenvermectins (TVMs), 13-oleandrosyl-oleandrosyloxy ST906 (1) and aromatic TVM B (2), were isolated from the fermentation broth of Streptomyces avermitilis HU02-06. Their structures were establis...
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Probing electrolyte effects on cation-enhanced CO2 reduction on copper in acidic media
Tuning the properties of the electric double layer via cations is a recognized approach for improving the efficiency of the CO2 reduction reaction (CO2RR). However, the mechanism behind cation-enhanced CO2RR kine...
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From Perspective of Hippocampal Plasticity: Function of Antidepressant Chinese Medicine **aoyaosan
The hippocampus is one of the most commonly studied brain regions in the context of depression. The volume of the hippocampus is significantly reduced in patients with depression, which severely disrupts hippo...
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Open AccessNovel radiopaque ethanol injection: physicochemical properties, animal experiments, and clinical application in vascular malformations
Despite the efficacy of absolute ethanol (EtOH), its radiolucency introduces several risks in interventional therapy for treating vascular malformations. This study aims to develop a novel radiopaque ethanol i...
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Article
Wave Attenuation and Turbulence Driven by Submerged Vegetation Under Current–Wave Flow
A set of laboratory experiments are carried out to investigate the effect of following/opposing currents on wave attenuation. Rigid vegetation canopies with aligned and staggered configurations were tested und...
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Urolithin A promotes atherosclerotic plaque stability by limiting inflammation and hypercholesteremia in Apolipoprotein E–deficient mice
Urolithin A (UroA), a dietary phytochemical, is produced by gut bacteria from fruits rich in natural polyphenols ellagitannins (ETs). The efficiency of ETs metabolism to UroA in humans depends on gut microbiot...
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A global survey on the use of the international classification of diseases codes for metabolic dysfunction-associated fatty liver disease
With the implementation of the 11th edition of the International Classification of Diseases (ICD-11) and the publication of the metabolic dysfunction-associated fatty liver disease (MAFLD) nomenclature in 2020...
