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    mTORC1-Dependent and GSDMD-Mediated Pyroptosis in Developmental Sevoflurane Neurotoxicity

    Developmental sevoflurane exposure leads to neuronal cell death, and subsequent learning and memory cognitive defects. The underlyi\ng mechanism remains to be elucidated. Gasdermin D (GSDMD)-mediated pyroptosi...

    Wang Wen-Yuan, Yi Wan-Qing, Hu Qi-Yun, Liu Yu-Si, Qian Shao-Jie in Molecular Neurobiology (2023)

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    Effects of Involuntary and Voluntary Exercise in Combination with Acousto-Optic Stimulation on Adult Neurogenesis in an Alzheimer's Mouse Model

    Single-factor intervention, such as physical exercise and auditory and visual stimulation, plays a positive role on the prevention and treatment of Alzheimer’s disease (AD); however, the therapeutic effects of...

    Wan-yi Li, Jun-yan Gao, Su-Yang Lin, Shao-tao Pan, in Molecular Neurobiology (2022)

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    Ginsenoside Rg1 Prevents Chemotherapy-Induced Cognitive Impairment: Associations with Microglia-Mediated Cytokines, Neuroinflammation, and Neuroplasticity

    Chemotherapy-induced cognitive impairment, also known as “chemobrain,” is a common side effect. The purpose of this study was to examine whether ginsenoside Rg1, a ginseng-derived compound, could prevent chemo...

    Dong-Dong Shi, Yu-Hua Huang, Cora Sau Wan Lai, Celia M. Dong in Molecular Neurobiology (2019)

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    Chemotherapy-Induced Cognitive Impairment Is Associated with Cytokine Dysregulation and Disruptions in Neuroplasticity

    Chemotherapy-induced cognitive impairment, often referred to as “chemobrain,” is a common side effect. In this study, mice received three intraperitoneal injections of a combination of docetaxel, adriamycin, a...

    Dong-Dong Shi, Yu-Hua Huang, Cora Sau Wan Lai, Celia M. Dong in Molecular Neurobiology (2019)