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286 Result(s)
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Article
Mechanical and dam** performances of TPMS lattice metamaterials fabricated by laser powder bed fusion
Lattice metamaterials based on three-period minimum surface (TPMS) are an effective means to achieve lightweight and high-strength materials which are widely used in various fields such as aerospace and ships....
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Precise separation and efficient recovery of Pd(II) from high-level liquid waste by XAD-based adsorbents
Efficient separation of palladium (Pd(II)) from high-level liquid waste (HLLW) not only helps the safe disposal of nuclear waste, but also is a vital important supplement to Pd(II) resources. Herein, 16 kinds ...
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Leveraging crystal symmetry for thermoelectric performance optimization in cubic GeSe
In thermoelectrics, the manipulation of crystal symmetry is instrumental in optimizing the electrical and thermal transport parameters. Within this context, the present study explored the largely overlooked hi...
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Open AccessAn intelligent threshold selection method to improve orbital angular momentum-encoded quantum key distribution under turbulence
High-dimensional quantum key distribution (HD-QKD) encoded by orbital angular momentum (OAM) presents significant advantages in terms of information capacity. However, perturbations caused by free-space atmosp...
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Article
Radical involved reactive wetting and retarding mechanism of alumina refractory ceramic by molten slags under weak static magnetic field
High alumina slag will cause severe corrosion at the interface of alumina refractory, and the wetting behavior of slag is a key factor influencing the corrosion resistance of refractory ceramics. The static ma...
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Article
Effect of Chinese Medicine in Patients with COVID-19: A Multi-center Retrospective Cohort Study
To evaluate the effectiveness and safety of Chinese medicine (CM) in the treatment of coronavirus disease 2019 (COVID-19) in China.
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Open AccessSerum cytokines and creatinine/cystatin C ratio as prognostic biomarkers in advanced cancer patients treated with anti-PD-1/PD-L1 therapy
Immune checkpoint inhibitors (ICIs), specifically targeting the programmed cell death protein-1 or its ligand (PD-1/PD-L1), have been extensively used in the treatment of a spectrum of malignancies, although t...
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Open AccessOsMAPK6 phosphorylation and CLG1 ubiquitylation of GW6a non-additively enhance rice grain size through stabilization of the substrate
The chromatin modifier GRAIN WEIGHT 6a (GW6a) enhances rice grain size and yield. However, little is known about its gene network determining grain size. Here, we report that MITOGEN-ACTIVED PROTEIN KINASE 6 (...
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Article
Trilaciclib dosage in Chinese patients with extensive-stage small cell lung cancer: a pooled pharmacometrics analysis
This study aimed to analyze potential ethnic disparities in the dose–exposure–response relationships of trilaciclib, a first-in-class intravenous cyclin-dependent kinase 4/6 inhibitor for treating chemotherapy...
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A mixed-valence polyoxometalate-based 3D inorganic framework cathode material for high-efficiency rechargeable AZIBs
The global trend towards new energy storage systems has stimulated the development of electrochemical energy storage technologies. Among these technologies, rechargeable aqueous zinc-ion batteries (AZIBs) have...
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Article
Open AccessCsn5 inhibits autophagy by regulating the ubiquitination of Atg6 and Tor to mediate the pathogenicity of Magnaporthe oryzae
Csn5 is subunit 5 of the COP9 signalosome (CSN), but the mechanism by which it strictly controls the pathogenicity of pathogenic fungi through autophagy remains unclear. Here, we found that Csn5 deficiency att...
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Article
Frontostriatal circuit dysfunction leads to cognitive inflexibility in neuroligin-3 R451C knockin mice
Cognitive and behavioral rigidity are observed in various psychiatric diseases, including in autism spectrum disorder (ASD). However, the underlying mechanism remains to be elucidated. In this study, we found ...
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Article
Open AccessQuercetin-loaded mesoporous nano-delivery system remodels osteoimmune microenvironment to regenerate alveolar bone in periodontitis via the miR-21a-5p/PDCD4/NF-κB pathway
Impaired osteo-/angiogenesis, excessive inflammation, and imbalance of the osteoimmune homeostasis are involved in the pathogenesis of the alveolar bone defect caused by periodontitis. Unfortunately, there is ...
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Preface to the special topic on metals and their compounds for lithium ion/metal batteries
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Advancements in machine learning for material design and process optimization in the field of additive manufacturing
Additive manufacturing technology is highly regarded due to its advantages, such as high precision and the ability to address complex geometric challenges. However, the development of additive manufacturing pr...
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Open AccessFabrication of levofloxacin-loaded porcine acellular dermal matrix hydrogel and functional assessment in urinary tract infection
Bacterial cystitis, a commonly occurring urinary tract infection (UTI), is renowned for its extensive prevalence and tendency to recur. Despite the extensive utilization of levofloxacin as a conventional thera...
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Open AccessHyperinsulinemia impairs decidualization via AKT-NR4A1 signaling: new insight into polycystic ovary syndrome (PCOS)-related infertility
Investigating the underlying molecular mechanisms responsible for endometrial dysfunction in women with PCOS is essential, particularly focusing on the role of hyperinsulinemia.
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Article
Impact of Annealing on the Melt Recrystallization of a-PDLA/α-PLLA Double-layered Films
Poly(lactic acid) (PLA) as a bio-based polymer with biodegradability and biocompatibility has attracted much attention. To manipulate its properties for different applications, regulation of crystal structure ...
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Real-time and selective control of shell deformation based on dynamic and subregional pressure response of flexible dies under magnetic field
Pressure-carrying properties of traditional flexible dies can hardly be controlled during the forming process of shell components. In this work, a forming method based on the subregional and dynamic pressure r...
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Article
ATG5 Knockdown Attenuates Ischemia‒Reperfusion Injury by Reducing Excessive Autophagy-Induced Ferroptosis
Autophagy has been described to be both protective and pathogenic in cerebral ischemia/reperfusion (I/R) injury. The underlying association between autophagy and ferroptosis in ischemic stroke has not yet been...