24 Result(s)
within
**ao-he Li
Science, Humanities and Social Sciences, multidisciplinary
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Article
Brain endothelial GSDMD activation mediates inflammatory BBB breakdown
The blood–brain barrier (BBB) protects the central nervous system from infections or harmful substances1; its impairment can lead to or exacerbate various diseases of the central nervous system2–4. However, the m...
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Creation of memory–memory entanglement in a metropolitan quantum network
Towards realizing the future quantum internet1,2, a pivotal milestone entails the transition from two-node proof-of-principle experiments conducted in laboratories to comprehensive multi-node set-ups on large sca...
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Open AccessStudy on blasting fragmentation mechanism of burnt rock in open-pit coal mine
A large number of burnt rocks in some open-pit mines in **njiang, Inner Mongolia and Ningxia have a great influence on the blasting effect. For this kind of rock, through the analysis of physical and chemical ...
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Article
Open AccessMagnaporthe oryzae effector MoSPAB1 directly activates rice Bsr-d1 expression to facilitate pathogenesis
Fungal pathogens typically use secreted effector proteins to suppress host immune activators to facilitate invasion. However, there is rarely evidence supporting the idea that fungal secretory proteins contrib...
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Open AccessDevelopment of machine learning prognostic models for overall survival of prostate cancer patients with lymph node-positive
Prostate cancer (PCa) patients with lymph node involvement (LNI) constitute a single-risk group with varied prognoses. Existing studies on this group have focused solely on those who underwent prostatectomy (R...
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Article
Open AccessGiant polarization ripple in transverse pyroelectricity
Pyroelectricity originates from spontaneous polarization variation, promising in omnipresent non-static thermodynamic energy harvesting. Particularly, changing spontaneous polarization via out-of-plane uniform...
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Article
Open AccessOropharyngeal administration of mother’s own milk influences levels of salivary sIgA in preterm infants fed by gastric tube
The aim of the present study was to explore the effect of oropharyngeal mother’s milk administration on salivary secretory immunoglobulin A (sIgA) levels in preterm infants fed by gastric tube. Infants (n = 13...
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Open AccessTNF antagonist sensitizes synovial fibroblasts to ferroptotic cell death in collagen-induced arthritis mouse models
Ferroptosis is a nonapoptotic cell death process that requires cellular iron and the accumulation of lipid peroxides. In progressive rheumatoid arthritis (RA), synovial fibroblasts proliferate abnormally in th...
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Open AccessAuthor Correction: Anisomycin prevents OGD-induced necroptosis by regulating the E3 ligase CHIP
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Article
Open AccessQuantitative evaluation of protective antibody response induced by hepatitis E vaccine in humans
Efficacy evaluation through human trials is crucial for advancing a vaccine candidate to clinics. Next-generation sequencing (NGS) can be used to quantify B cell repertoire response and trace antibody lineages...
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Article
Open AccessMaternal control of suspensor programmed cell death via gibberellin signaling
Plant embryos are generated and develop in a stable and well-protected microenvironment surrounded by maternal tissue, which is vital for embryogenesis. However, the signaling mechanisms responsible for matern...
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Open AccessA ZEB1/p53 signaling axis in stromal fibroblasts promotes mammary epithelial tumours
Accumulating evidence indicates that the zinc-finger transcription factor ZEB1 is predominantly expressed in the stroma of several tumours. However, the role of stromal ZEB1 in tumour progression remains unexp...
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Article
Open AccessRing synthetic chromosome V SCRaMbLE
Structural variations (SVs) exert important functional impacts on biological phenotypic diversity. Here we show a ring synthetic yeast chromosome V (ring_synV) can be used to continuously generate complex geno...
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Open AccessAnisomycin prevents OGD-induced necroptosis by regulating the E3 ligase CHIP
Necroptosis is an essential pathophysiological process in cerebral ischemia-related diseases. Therefore, targeting necroptosis may prevent cell death and provide a much-needed therapy. Ansiomycin is an inhibit...
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Open AccessA systems pharmacology-oriented discovery of a new therapeutic use of the TCM formula Liuweiwuling for liver failure
Multiple components of traditional Chinese medicine (TCM) formulae determine their treatment targets for multiple diseases as opposed to a particular disease. However, discovering the unexplored therapeutic po...
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Article
Open AccessNon-equilibrium synergistic effects in atmospheric pressure plasmas
Non-equilibrium is one of the important features of an atmospheric gas discharge plasma. It involves complicated physical-chemical processes and plays a key role in various actual plasma processing. In this re...
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Open AccesspGlyco 2.0 enables precision N-glycoproteomics with comprehensive quality control and one-step mass spectrometry for intact glycopeptide identification
The precise and large-scale identification of intact glycopeptides is a critical step in glycoproteomics. Owing to the complexity of glycosylation, the current overall throughput, data quality and accessibilit...
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Open AccessVisceral Adiposity and Anthropometric Indicators as Screening Tools of Metabolic Syndrome among Low Income Rural Adults in **njiang
Most previous studies on metabolic syndrome (MetS) examined urban and high income settings. We thus investigated the prevalence of MetS among a multi-ethnic population living in a low income rural area and exp...
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Open AccessEpitomics: IgG-epitome decoding of E6, E7 and L1 proteins from oncogenic human papillomavirus type 58
To enable rational multi-epitope vaccine and diagnostic antigen design, it is imperative to delineate complete IgG-epitome of the protein. Here, we describe results of IgG-epitome decoding of three proteins fr...
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Divergent clonal selection dominates medulloblastoma at recurrence
The development of targeted anti-cancer therapies through the study of cancer genomes is intended to increase survival rates and decrease treatment-related toxicity. We treated a transposon–driven, functional ...
