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Role of thrombospondin-1 in high-salt–induced mesenteric artery endothelial impairment in rats

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  1. Article

    Open Access

    Postnatal treatment and evolution patterns of giant fetal hepatic hemangioma: a case series of 29 patients

    To explore the clinical characteristics, postnatal treatment and prognosis of giant fetal hepatic hemangioma (GFHH).

    Lu-lu **e, Yan-bing Huang, Kui-ran Dong, Shao-bo Yang, Chun Shen in BMC Pediatrics (2024)

  2. Article

    Author Correction: Darinaparsin (ZIO-101) enhances the sensitivity of small-cell lung cancer to PARP inhibitors

    Guo-zhen Cao, Li-ying Ma, Zong-hui Zhang, **ao-lin Wang in Acta Pharmacologica Sinica (2023)

  3. Article

    Open Access

    Safety and feasibility of the transoral endoscopic thyroidectomy vestibular approach with neuroprotection techniques for papillary thyroid carcinoma

    This study aimed to evaluate the feasibility and safety of the trans-oral endoscopic thyroidectomy vestibular approach (TOETVA) with neuroprotection techniques for the surgical management of papillary thyroid ...

    Zhen-**n Chen, Ya-Min Song, **g-Bao Chen, **ao-Bo Zhang, Feng-Shun Pang in BMC Surgery (2022)

  4. Article

    Open Access

    Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma

    HDAC inhibitors (HDACis) have been intensively studied for their roles and potential as drug targets in T-cell lymphomas and other hematologic malignancies. Bisthianostat is a novel bisthiazole-based pan-HDACi...

    Yu-bo Zhou, Yang-ming Zhang, Hong-hui Huang, Li-**g Shen in Acta Pharmacologica Sinica (2022)

  5. Article

    Open Access

    High prevalence and low awareness of hyperuricemia in hypertensive patients among adults aged 50–79 years in Southwest China

    This study was aimed to assess the prevalence of hyperuricemia and its associated risk factors among hypertensive patients in Southwest China.

    Yang Zhang, Feng-Qin Nie, **ao-Bo Huang, Weiwei Tang in BMC Cardiovascular Disorders (2022)

  6. Article

    Open Access

    Misdiagnosed tuberculosis being corrected as Nocardia farcinica infection by metagenomic sequencing: a case report

    Disseminated nocardiosis is liable to be misdiagnosed owing to the non-specific clinical manifestations and laboratory/imaging findings. Metagenomic next-generation sequencing (mNGS) is a culture-independent a...

    Lei Pan, **ao-hong Pan, Jie-kun Xu, **ao-qing Huang, Jun-ke Qiu in BMC Infectious Diseases (2021)

  7. Article

    Open Access

    Clinical effect and antiviral mechanism of T-705 in treating severe fever with thrombocytopenia syndrome

    Severe fever with thrombocytopenia syndrome (SFTS) virus (SFTSV) is an emerging tick-borne virus with high fatality and an expanding endemic. Currently, effective anti-SFTSV intervention remains unavailable. F...

    Hao Li, **a-Ming Jiang, Ning Cui, Chun Yuan in Signal Transduction and Targeted Therapy (2021)

  8. Article

    Open Access

    Dilation of the cystic duct confluence in laparoscopic common bile duct exploration and stone extraction in patients with secondary choledocholithiasis

    Many options exist for the management of cholelithiasis and secondary choledocholithiasis. Among them, laparoscopic common bile duct exploration (LCBDE) with choledocotomy followed by laparoscopic cholecystect...

    **ao-Bin Yang, An-Shu Xu, Jian-Gang Li, Yong-** Xu, De-Song Xu in BMC Surgery (2020)

  9. Article

    Open Access

    Unbiased screening reveals that blocking exportin 1 overcomes resistance to PI3Kα inhibition in breast cancer

    Xue-Ling Liu, Bo-Bo Wang, Yi Wang in Signal Transduction and Targeted Therapy (2019)

  10. Article

    Open Access

    Liver graft rejection following immune checkpoint inhibitors treatment: a review

    Immune checkpoint inhibitors (ICIs) have demonstrated remarkable efficacy in a variety of solid tumors; nonetheless, they have not been well investigated and are still recognized as a relative contraindication...

    Bo Hu, **ao-Bo Yang, **n-Ting Sang in Medical Oncology (2019)

  11. Article

    Efficacy of Different Types of Exercise-Based Cardiac Rehabilitation on Coronary Heart Disease: a Network Meta-analysis

    Exercise-based cardiac rehabilitation (CR) has been recognized as an essential component of the treatment for coronary heart disease (CHD). Determining the efficacy of modern alternative treatment methods is t...

    Tian-li **a, Fang-yang Huang, Yong Peng in Journal of General Internal Medicine (2018)

  12. Article

    Open Access

    Vaccination demonstration zone successfully controls rabies in Guangxi Province, China

    Guangxi is the province most seriously affected by rabies virus (RABV) in China. Those most affected by RABV each year are people in rural areas, where dogs are the main cause of human infection with the virus.

    **an-Kai Wei, Yi **ong, **ao-Ning Li, Min Zheng, Yan Pan in BMC Infectious Diseases (2018)

  13. Article

    Open Access

    Ideal T1 laminar screw fixation based on computed tomography morphometry

    The application of laminar screws is an alternative fixation for the first thoracic vertebra (T1). This paper is to determine the anatomical characteristics for adequate laminar screw fixation, and present a m...

    **ao-Bo Wang, **n Zheng, Hou-Qing Long, Wen-Li Chen in BMC Musculoskeletal Disorders (2017)

  14. Article

    In vitro assessment of the glucose-lowering effects of berberrubine-9-O-β-D-glucuronide, an active metabolite of berberrubine

    Berberrubine (BRB) is the primary metabolite of berberine (BBR) that has shown a stronger glucose-lowering effect than BBR in vivo. On the other hand, BRB is quickly and extensively metabolized into berberrubine-...

    Na Yang, Run-bin Sun, **ng-long Chen, Le Zhen, Chun Ge in Acta Pharmacologica Sinica (2017)

  15. Article

    Biochemical features of the adhesion G protein-coupled receptor CD97 related to its auto-proteolysis and HeLa cell attachment activities

    CD97 belongs to the adhesion GPCR family characterized by a long ECD linked to the 7TM via a GPCR proteolytic site (GPS) and plays important roles in modulating cell migration and invasion. CD97 (EGF1-5) is a ...

    Li-yun Yang, **ao-fang Liu, Yang Yang, Lin-lin Yang in Acta Pharmacologica Sinica (2017)

  16. Article

    Open Access

    Fatty liver index correlates with non-alcoholic fatty liver disease, but not with newly diagnosed coronary artery atherosclerotic disease in Chinese patients

    Fatty liver index (FLI) was recently established to predict non-alcoholic fatty liver disease (NAFLD) in general population, which is known to be associated with coronary artery atherosclerotic disease (CAD).

    Zhao-Yan Jiang, Chen-Ying Xu, **an-**ng Chang, Wei-Wei Li in BMC Gastroenterology (2013)

  17. Article

    Strontium ranelate reduces cartilage degeneration and subchondral bone remodeling in rat osteoarthritis model

    To investigate whether strontium ranelate (SR), a new antiosteoporotic agent, could attenuate cartilage degeneration and subchondral bone remodeling in osteoarthritis (OA).

    De-gang Yu, Hui-feng Ding, Yuan-qing Mao, Ming Liu, Bo Yu in Acta Pharmacologica Sinica (2013)

  18. Article

    Pharmacokinetic interactions induced by content variation of major water-soluble components of Danshen preparation in rats

    To investigate the pharmacokinetic interactions induced by content variation of the main water-soluble components of Danshen injection in rats.

    Bo-bo Chang, Lin Zhang, Wan-wen Cao, Yuan Cao, Wen-liang Yang in Acta Pharmacologica Sinica (2010)

  19. Article

    L-carnitine and taurine synergistically inhibit the proliferation and osteoblastic differentiation of vascular smooth muscle cells

    To investigate the synergistic action of L-carnitine (LC) and taurine (TAU) on the proliferation and osteoblastic differentiation of vascular smooth muscle cells (VSMCs).

    Hui **e, Bing Yang, **n-min Zhou, Feng-lin Song, Jian-ming Li in Acta Pharmacologica Sinica (2010)