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Article
Regioselective cation exchange reaction for photoelectrochemical water splitting
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Article
Airways epithelial exposure to Streptococcus pneumoniae in the presence of the alarmin IL-33 induces a novel subset of pro-inflammatory ILC2s promoting a mixed inflammatory response
We have previously shown that asthma-like airways inflammation may be induced by topical exposure to respiratory tract pathogens such as S. pneumoniae (SP) in concert with epithelial alarmins such as IL-33. Detai...
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Article
A global survey on the use of the international classification of diseases codes for metabolic dysfunction-associated fatty liver disease
With the implementation of the 11th edition of the International Classification of Diseases (ICD-11) and the publication of the metabolic dysfunction-associated fatty liver disease (MAFLD) nomenclature in 2020...
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Article
Methyl Jasmonate Treatment Relieves Chilling Injury and Improves the Postharvest Quality of Snap Bean by Regulating Antioxidant Metabolism
Snap bean (Phaseolus vulgaris L.) is very sensitive to low temperature during postharvest storage. Methyl jasmonate (MeJA) is a volatile hormone ubiquitous in many kinds of plants and plays important role in regu...
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Article
Open AccessMulti-modal molecular determinants of clinically relevant osteoporosis subtypes
Due to a rapidly aging global population, osteoporosis and the associated risk of bone fractures have become a wide-spread public health problem. However, osteoporosis is very heterogeneous, and the existing s...
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Article
Expression of mitochondrial transcription factor A in granulosa cells: implications for oocyte maturation and in vitro fertilization outcomes
In vitro fertilization-embryo transfer (IVF-ET) is a widely used treatment for infertility, with oocyte maturation and quality having a significant impact on oocyte fertilization, embryo development, and fetal...
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Article
Open AccessGut microbiota impacts bone via Bacteroides vulgatus-valeric acid-related pathways
Although the gut microbiota has been reported to influence osteoporosis risk, the individual species involved, and underlying mechanisms, remain largely unknown. We performed integrative analyses in a Chinese ...
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Article
Open AccessCamrelizumab combined with apatinib in patients with first-line platinum-resistant or PD-1 inhibitor resistant recurrent/metastatic nasopharyngeal carcinoma: a single-arm, phase 2 trial
Immunotherapy combined with antiangiogenic targeted therapy has improved the treatment of certain solid tumors, but effective regimens remain elusive for refractory recurrent/metastatic nasopharyngeal carcinom...
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Article
The tumor immune microenvironment of nasopharyngeal carcinoma after gemcitabine plus cisplatin treatment
Gemcitabine plus cisplatin (GP) chemotherapy is the standard of care for nasopharyngeal carcinoma (NPC). However, the mechanisms underpinning its clinical activity are unclear. Here, using single-cell RNA sequ...
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Article
Inoculation with Rhizophagus intraradices Confers Drought Stress Tolerance in Oat by Improving Nitrogen and Phosphorus Nutrition
This study determined the effects of arbuscular mycorrhizal (AM) fungi inoculation on the N and P contents in the soil–plant continuum and its subsequent effect on oat grain yield under drought stress. Separa...
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Article
Synthesis of Mesoporous Rod-Like MnC2O4/MWCNT Composite Anode Material for Lithium-Ion Batteries
MnC2O4 is a promising anode material for Li-ion batteries. However, MnC2O4 suffers from poor performance due to its low conductivity and volume change in cycles. Herein, a strategy based on the surface charge and...
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Article
Photonuclear production of nuclear isomers using bremsstrahlung induced by laser-wakefield electrons
In this study, we theoretically investigate the feasibility of using laser-wakefield accelerated (LWFA) electrons for the photonuclear measurement of nuclear isomers according to the characteristics of the ele...
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Article
Open AccessPulmonary artery sarcoma: an unexpected settler in the right ventricular outflow tract
Pulmonary artery sarcoma (PAS) is a sporadic malignant tumor that mainly originates from the pulmonary arteries. However, PAS may also involve the right ventricular outflow tract (RVOT) and lead to obstruction...
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Article
Open AccessCEBPD is a master transcriptional factor for hypoxia regulated proteins in glioblastoma and augments hypoxia induced invasion through extracellular matrix-integrin mediated EGFR/PI3K pathway
Hypoxia contributes to the initiation and progression of glioblastoma by regulating a cohort of genes called hypoxia-regulated genes (HRGs) which form a complex molecular interacting network (HRG-MINW). Transc...
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Article
Open AccessThe clinical implications and molecular features of intrahepatic cholangiocarcinoma with perineural invasion
Perineural invasion (PNI) is associated with metastasis in malignancies, including intrahepatic cholangiocarcinoma (ICC), and is correlated with poor prognosis.
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Article
Open AccessAssociation of mitochondrial homeostasis and dynamic balance with malignant biological behaviors of gastrointestinal cancer
Mitochondria determine the physiological status of most eukaryotes. Mitochondrial dynamics plays an important role in maintaining mitochondrial homeostasis, and the disorder in mitochondrial dynamics could aff...
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Article
Evaluation of the diagnostic performance of the EFSUMB CEUS Pancreatic Applications guidelines (2017 version): a retrospective single-center analysis of 455 solid pancreatic masses
To explore the diagnostic performance of EFSUMB CEUS Pancreatic Applications guidelines (version 2017) before and after the addition of iso-enhancement and very fast/fast washout as supplementary diagnostic cr...
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Article
The taxonomic revision of Melanogaster (Paxillaceae, Boletales) in China based on molecular and morphological evidence
The sequestrate genus Melanogaster is rich in mainland China. A total of ten taxa are supported by molecular evidence in this study, including five known species, four new species, and one putatively new species ...
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Article
Aging induces severe SIV infection accompanied by an increase in follicular CD8+ T cells with overactive STAT3 signaling
The number of elderly people living with HIV is increasing globally, and the condition of this population is relatively complicated due to the dual effects of aging and HIV infection. However, the impact of HI...
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Article
High-performance, three-dimensional and porous K3V2(PO4)3/C cathode material for potassium-ion batteries
K3V2(PO4)3 (KVP) can be employed as a potential cathode material for potassium-ion batteries owing to its high theoretical capacity (106 mA h g−1). However, the inherently poor electronic conductivity of KVP seve...