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  1. Article

    Open Access

    Renin-angiotensin system inhibitors improve the survival of cholangiocarcinoma: a propensity score-matched cohort study

    Hypertension is a risk factor for cholangiocarcinoma (CCA). The effect of anti-hypertensive drugs on the prognosis of CCA is not clear.

    **ao-Xu Zhu, Jian-Hui Li, Peng Fang, **ao-Fei Qu, Li-Jian Liang, Jia-Ming Lai in BMC Cancer (2023)

  2. Article

    Open Access

    Chidamide increases the sensitivity of refractory or relapsed acute myeloid leukemia cells to anthracyclines via regulation of the HDAC3 -AKT-P21-CDK2 signaling pathway

    Induction therapy for acute myeloid leukemia (AML) is an anthracycline-based chemotherapy regimen. However, many patients experience a relapse or exhibit refractory disease (R/R). There is an urgent need for m...

    Hao Wang, Yu-chen Liu, Cheng-ying Zhu in Journal of Experimental & Clinical Cancer … (2020)

  3. Article

    Open Access

    MFAP5 facilitates the aggressiveness of intrahepatic Cholangiocarcinoma by activating the Notch1 signaling pathway

    Intrahepatic cholangiocarcinoma (ICC) is the second most common primary liver cancer. The dismal outcome of ICC patients is due to lack of early diagnosis, the aggressive biological behavior of ICC and the lac...

    Jian-Hui Li, **ao-Xu Zhu, Fu-** Li in Journal of Experimental & Clinical Cancer … (2019)

  4. No Access

    Article

    BTG2 Is Down-Regulated and Inhibits Cancer Stem Cell-Like Features of Side Population Cells in Hepatocellular Carcinoma

    Our previous study found that B cell translocation gene 2 (BTG2) was hyper-methylated and down-regulated in side population (SP) cells of hepatocellular carcinoma (HCC) cell line. However, its clinical signifi...

    Chen-Song Huang, **g-Ming Zhai, **ao-Xu Zhu in Digestive Diseases and Sciences (2017)

  5. No Access

    Article

    Hepatoprotective Effect of Ulinastatin in a Rat Model of Major Hepatectomy After Obstructive Jaundice

    To date, major hepatectomy with obstructive jaundice is still a highly risky and difficult surgery because of the high rate of complications. An excessive inflammatory response may be the primary hindrance to ...

    Xun Li, **g Li, Yang-Jie Ou, **ao-Xu Zhu, **ao-Yu Yin in Digestive Diseases and Sciences (2015)

  6. No Access

    Article

    Hormone replacement therapy and risk of meningioma in women: a meta-analysis

    The relationship between hormone replacement therapy (HRT) and the incidence of meningioma in women has been investigated in several epidemiologic studies, but their results were not entirely consistent. Here,...

    Zuo-Xu Fan, Jian Shen, Yao-Yao Wu, Hai Yu, Yu Zhu, Ren-Ya Zhan in Cancer Causes & Control (2013)