9 Result(s)
within
**ao-Xu Zhu
Biochemistry, general
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Article
Open AccessSUMO specific peptidase 3 halts pancreatic ductal adenocarcinoma metastasis via deSUMOylating DKC1
In the past few decades, advances in the outcomes of patients suffering from pancreatic ductal adenocarcinoma (PDAC) have lagged behind these gained in the treatment of many other malignancies. Although the pi...
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Article
Rapid detection of EGFR mutation in CTCs based on a double spiral microfluidic chip and the real-time RPA method
Circulating tumor cells (CTCs) are cells shed from primary or metastatic tumors and spread into the peripheral bloodstream. Mutation detection in CTCs can reveal vital genetic information about the tumors and ...
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Article
Open AccessLncRNA H19 governs mitophagy and restores mitochondrial respiration in the heart through Pink1/Parkin signaling during obesity
Maintaining proper mitochondrial respiratory function is crucial for alleviating cardiac metabolic disorders during obesity, and mitophagy is critically involved in this process. Long non-coding RNA H19 (H19) ...
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Article
BTG2 Is Down-Regulated and Inhibits Cancer Stem Cell-Like Features of Side Population Cells in Hepatocellular Carcinoma
Our previous study found that B cell translocation gene 2 (BTG2) was hyper-methylated and down-regulated in side population (SP) cells of hepatocellular carcinoma (HCC) cell line. However, its clinical signifi...
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Article
CDK inhibitor SU9516 induces tetraploid blastocyst formation from parthenogenetically activated porcine embryos
To examine the effect of SU9516, a cyclin-dependent kinase inhibitor, on the induction of tetraploid blastocyst formation in porcine embryos by parthenogenetic activation.
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Article
RepSox improves viability and regulates gene expression in rhesus monkey–pig interspecies cloned embryos
To investigate the effect of the small molecule, RepSox, on the expression of developmentally important genes and the pre-implantation development of rhesus monkey–pig interspecies somatic cell nuclear transfe...
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Article
The developmental competence of oocytes parthenogenetically activated by an electric pulse and anisomycin treatment
The aim of this study was to investigate the developmental competence of oocytes parthenogenetically activated by an electric pulse (EP) and treated with anisomycin and to determine whether this method is appl...
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Article
PCI-24781 can improve in vitro and in vivo developmental capacity of pig somatic cell nuclear transfer embryos
To examine the effect of PCI-24781 (abexinostat) on the blastocyst formation rate in pig somatic cell nuclear transferred (SCNT) embryos and acetylation levels of the histone H3 lysine 9 and histone H4 lysine 12.
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Article
Hepatoprotective Effect of Ulinastatin in a Rat Model of Major Hepatectomy After Obstructive Jaundice
To date, major hepatectomy with obstructive jaundice is still a highly risky and difficult surgery because of the high rate of complications. An excessive inflammatory response may be the primary hindrance to ...
