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  1. Article

    Author Correction: CB2 receptor activation inhibits the phagocytic function of microglia through activating ERK/AKT-Nurr1 signal pathways

    Qi-wen Han, Qian-hang Shao, **ao-tong Wang, Kai-li Ma… in Acta Pharmacologica Sinica (2024)

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  2. Article

    Open Access

    Lactobacillus rhamnosus GG ameliorates hyperuricemia in a novel model

    Hyperuricemia (HUA) is a metabolic syndrome caused by abnormal purine metabolism. Although recent studies have noted a relationship between the gut microbiota and gout, whether the microbiota could ameliorate ...

    Yang Fu, Yong-Song Chen, Dai-Yang **a, **ao-Dan Luo… in npj Biofilms and Microbiomes (2024)

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    Article

    CB2 receptor activation inhibits the phagocytic function of microglia through activating ERK/AKT-Nurr1 signal pathways

    Neuroinflammation is closely related to the pathogenesis of neurodegenerative diseases. Activation of microglia, the resident immune cells in CNS, induces inflammatory responses, resulting in the release of ne...

    Qi-wen Han, Qian-hang Shao, **ao-tong Wang, Kai-li Ma… in Acta Pharmacologica Sinica (2022)

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    Article

    FK228 potentiates topotecan activity against small cell lung cancer cells via induction of SLFN11

    The response rate of topotecan, as a second-line chemotherapeutic drug for small cell lung cancer, is ~20%. DNA/RNA helicase SLFN11 (schlafen family member 11), a member of the Schlafen (SLFN) family, is a cru...

    Yan-** Yin, Li-ying Ma, Guo-zhen Cao, **g-han Hua… in Acta Pharmacologica Sinica (2022)

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    Article

    Diosmetin has therapeutic efficacy in colitis regulating gut microbiota, inflammation, and oxidative stress via the circ-Sirt1/Sirt1 axis

    Diosmetin (3',5,7 -trihydroxy-4'-methoxy flavone) is a natural flavonoid compound in the citrus species, it exhibits a variety of pharmacological activities, but little is known of its effects on colitis. In t...

    Hai-long Li, Yi-ying Wei, **ao-he Li, Shan-shan Zhang… in Acta Pharmacologica Sinica (2022)

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    Article

    Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice

    Gluconeogenesis is a major source of hyperglycemia in patients with type 2 diabetes mellitus (T2DM), thus targeting gluconeogenesis to suppress glucose production is a promising strategy for anti-T2DM drug dis...

    Ting-ting Zhou, Tong Zhao, Fei Ma, Yi-nan Zhang, **g Jiang… in Acta Pharmacologica Sinica (2019)

  7. Article

    Open Access

    Catalogue of antibiotic resistome and host-tracking in drinking water deciphered by a large scale survey

    Excesses of antibiotic resistance genes (ARGs), which are regarded as emerging environmental pollutants, have been observed in various environments. The incidence of ARGs in drinking water causes potential ris...

    Li** Ma, Bing Li, **ao-Tao Jiang, Yu-Lin Wang, Yu **a, An-Dong Li… in Microbiome (2017)

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    Article

    Paenibacillus oryzisoli sp. nov., isolated from the rhizosphere of rice

    A novel bacterium, strain 1ZS3-15T, was isolated from rhizosphere of rice. Its taxonomic position was investigated using a polyphasic approach. The novel strain was observed to be Gram-stain positive, spore-formi...

    Jun Zhang, **ao-Tong Ma, Jun-Sheng Gao, Cai-Wen Zhang… in Antonie van Leeuwenhoek (2017)

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    Article

    Intra-host dynamics of Ebola virus during 2014

    Since 2013, West Africa has encountered the largest Ebola virus (EBOV) disease outbreak on record, and Sierra Leone is the worst-affected country, with nearly half of the infections. By means of next-generatio...

    Ming Ni, Chen Chen, Jun Qian, Hai-**a **ao, Wei-Feng Shi, Yang Luo… in Nature Microbiology (2016)