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Article
Open AccessSynthetic macrolides overcoming MLSBK-resistant pathogens
Conventional macrolide-lincosamide-streptogramin B-ketolide (MLSBK) antibiotics are unable to counter the growing challenge of antibiotic resistance that is conferred by the constitutive methylation of rRNA base ...
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Article
Open AccessLactobacillus rhamnosus GG ameliorates hyperuricemia in a novel model
Hyperuricemia (HUA) is a metabolic syndrome caused by abnormal purine metabolism. Although recent studies have noted a relationship between the gut microbiota and gout, whether the microbiota could ameliorate ...
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Article
Feeding experience on hairy vetch induces a loss of host-specific adaptation to maize and changes in the gut microbiota communities of the fall armyworm
Develo** ecological control technologies against the fall armyworms (FAWs) is crucial. The ecological role of green manure crops has gained attention for their indirect contribution to enhancing crop resista...
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Article
First report of mulberry vein banding-associated virus infecting Nicotiana tabacum in China
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Article
First report of tobacco vein banding mosaic virus and chilli veinal mottle virus infecting Solanum muricatum in China
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Article
Open AccessFBXW7 gene polymorphism is associated with type 2 diabetes in the Uygur population in **njiang, China
FBXW7 gene expression is positively correlated with glycolipid metabolism and is associated with diabetes in animal models. In the current study, we focused on exploring whether genetic variants of the FBXW7 g...
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Article
AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1
The sympathetic nervous system–catecholamine–uncoupling protein 1 (UCP1) axis plays an essential role in non-shivering adaptive thermogenesis. However, whether there exists a direct effector that physically co...
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Article
Open AccessTBL2 methylation is associated with hyper-low-density lipoprotein cholesterolemia: a case-control study
HMGCR, SCAP, SREBF1, SREBF2 and TBL2 are well-known genes that are involved in the process of lipid metabolism. However, it is not known whether epigenetic changes of these genes are associated with lipid metabol...
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Article
Open AccessSOAT1 methylation is associated with coronary heart disease
This study was designed to investigate whether differential DNA methylationin of cholesterol absorption candidate genes can function as a biomarker for patients with coronary heart disease (CHD).
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Article
Cultivation-dependent and high-throughput sequencing approaches studying the co-occurrence of antibiotic resistance genes in municipal sewage system
During the past years, antibiotic-resistant bacteria (ARB) leading for the spreading of antibiotic resistance genes (ARGs) became a global problem, especially multidrug-resistant (MDR) bacteria are considered ...
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Article
Paenibacillus oryzisoli sp. nov., isolated from the rhizosphere of rice
A novel bacterium, strain 1ZS3-15T, was isolated from rhizosphere of rice. Its taxonomic position was investigated using a polyphasic approach. The novel strain was observed to be Gram-stain positive, spore-formi...
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Article
Intra-host dynamics of Ebola virus during 2014
Since 2013, West Africa has encountered the largest Ebola virus (EBOV) disease outbreak on record, and Sierra Leone is the worst-affected country, with nearly half of the infections. By means of next-generatio...
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Article
Open AccessThe association of cholesterol absorption gene Numb polymorphism with Coronary Artery Disease among Han Chinese and Uighur Chinese in **njiang, China
Hypercholesterolemia is a major risk factor for coronary artery disease (CAD). As Numb is an important regulating factor for intestinal cholesterol absorption and plasma cholesterol level, the aim of the prese...
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Article
Open AccessHuman adipose-derived stem cells partially rescue the stroke syndromes by promoting spatial learning and memory in mouse middle cerebral artery occlusion model
Growing evidence has brought stem cell therapy to the forefront as new promising approaches towards stroke treatment. Of all candidate seeding cells, adipose-derived stem cells (ADSCs) are considered as one of...
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Article
Long-Term Rice and Green Manure Rotation Alters the Endophytic Bacterial Communities of the Rice Root
This study focuses on the effects of long-term rice rotated with milk vetch being as green manure on the composition of bacteria in rice roots. The endophytic bacterial communities in rice roots of the rice–ri...
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Article
Open AccessGenetic variation in Tanis was associated with elevating plasma triglyceride level in Chinese nondiabetic subjects
The association of genetic polymorphisms of Tanis with triglyceride concentration in human has not been thoroughly examined. We aimed to investigate the relationship between triglyceride concentrations and Tan...
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Article
Open AccessThe balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies
Reproducibility is a fundamental requirement in scientific experiments. Some recent publications have claimed that microarrays are unreliable because lists of differentially expressed genes (DEGs) are not repr...
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Chapter and Conference Paper
On the Potential of K-Nutrition and the Requirement of K-Fertilizer in Important Paddy Soils of China
The appearing of potassium deficient symbols on rice plant and the good response of rice crops to potassium fertilizer have been recently revealed in important types of the paddy soil in China(l).