18 Result(s)

Article

New clinical trial design in precision medicine: discovery, development and direction

In the era of precision medicine, it has been increasingly recognized that individuals with a certain disease are complex and different from each other. Due to the underestimation of the significant heterogene...

**ao-Peng Duan, Bao-Dong Qin, **ao-Dong Jiao… in Signal Transduction and Targeted Therapy (2024)

Article

Soluble CD4 effectively prevents excessive TLR activation of resident macrophages in the onset of sepsis

T lymphopenia, occurring in the early phase of sepsis in response to systemic inflammation, is commonly associated with morbidity and mortality of septic infections. We have previously shown that a sufficient ...

Sheng-yuan Zhang, Qiu-** Xu, Li-na Shi… in Signal Transduction and Targeted Therapy (2023)

Article

The association of dietary intake of riboflavin and thiamine with kidney stone: a cross-sectional survey of NHANES 2007–2018

Kidney stone disease (KSD) is a common condition that affects 10% population in the United States (US). The relationship between thiamine and riboflavin intake and KSD has not been well-studied. We aimed to in...

**ng-peng Di, **ao-shuai Gao, Li-yuan **ang, **n Wei in BMC Public Health (2023)

Article

Retraction Note: LINC01410-miR-532-NCF2-NF-kB feedback loop promotes gastric cancer angiogenesis and metastasis

Jia-**ng Zhang, Zhen-Hua Chen, Dong-Liang Chen, **ao-Peng Tian, Chen-Yuan Wang… in Oncogene (2023)

Article

Efficacy and safety of Tibetan medicine Qingpeng ointment for acute gouty arthritis: protocol for a multi-center, randomized, double-blind, placebo-controlled trial

Acute gouty arthritis (AGA) is an inflammatory arthritis clinically characterized by severe pain, swelling, and restricted movement of joints, which may cause physical disability and decrease quality of life. ...

Ya-xi Shang, **a Dong, Zhi-min **e, **ao-peng Li, **n-chang Wang, Ji-yong Huang… in Trials (2022)

Article

Predictive performances of ALS and BLS termination of resuscitation rules in out-of-hospital cardiac arrest for different resuscitation protocols

Resuscitation guidance has advanced; however, the predictive performance of the termination of resuscitation (TOR) rule has not been validated for different resuscitation protocols published by the American He...

Yu-Yuan Lin, Yin-Yu Lai, Hung-Chieh Chang, Chien-Hsin Lu… in BMC Emergency Medicine (2022)

Article

Protective role of berberine in isoprenaline-induced cardiac fibrosis in rats

Cardiac fibrosis is a crucial aspect of cardiac remodeling that can severely affect cardiac function. Cardiac fibroblasts surely influence this process. Besides, macrophage plays an essential role in cardiac r...

Yan Che, Di-Fei Shen, Zhao-Peng Wang, Ya-Ge **… in BMC Cardiovascular Disorders (2019)

Article

RETRACTED ARTICLE: LINC01410-miR-532-NCF2-NF-kB feedback loop promotes gastric cancer angiogenesis and metastasis

Dysregulation of non-coding RNAs, including miRNAs and lncRNAs has been reported to play vital roles in gastric cancer (GC) carcinogenesis, but the mechanism involved is largely unknown. Using the cancer genom...

Jia-**ng Zhang, Zhen-Hua Chen, Dong-Liang Chen, **ao-Peng Tian, Chen-Yuan Wang… in Oncogene (2018)

Article

A novel model for evaluating thrombolytic therapy in dogs with ST-elevation myocardial infarction

There is still no standard large animal model for evaluating the effectiveness of potential thrombolytic therapies. Here, we aimed to develop a new beagle model with ST-elevation myocardial infarction (STEMI) ...

Hong Zhang, Yong-chun Cui, Yi Tian, Wei-min Yuan… in BMC Cardiovascular Disorders (2016)

Article

Detection of activated KRAS from cancer patient peripheral blood using a weighted enzymatic chip array

The KRAS oncogene was one of the earliest discoveries of genetic alterations in colorectal and lung cancers. Moreover, KRAS somatic mutations might be used for predicting the efficiency of anti-EGFR therapeutic d...

Ming-Yii Huang, Hsueh-Chiao Liu, Li-Chen Yen… in Journal of Translational Medicine (2014)

Article

Basic research and clinical applications of bisphosphonates in bone disease: what have we learned over the last 40 years?

It is now 40 years since bisphosphonates (BPs) were first used in the clinic. So, it is timely to provide a brief review of what we have learned about these agents in bone disease. BPs are bone-specific and ha...

**ao-Long Xu, Wen-Long Gou, Ai-Yuan Wang, Yu Wang… in Journal of Translational Medicine (2013)

Article

Serum dihydroxyacetone kinase peptide m/z 520.3 as predictor of disease severity in patients with compensated chronic hepatitis B

Due to known limitations of liver biopsy, reliable non-invasive serum biomarkers for chronic liver diseases are needed. We performed serum peptidomics for such investigation in compensated chronic hepatitis B ...

Ming-Yi Xu, **ao-Fang Jia, Ying Qu, Rui-Dan Zheng… in Journal of Translational Medicine (2013)

Article

A novel tumor suppressor gene ECRG4 interacts directly with TMPRSS11A (ECRG1) to inhibit cancer cell growth in esophageal carcinoma

The esophageal carcinoma related gene 4 (ECRG4) was initially identified and cloned from human normal esophageal epithelium in our laboratory (GenBank accession no.AF325503). ECRG4 has been described as a nove...

Lin-wei Li, Yuan-yuan Li, **ao-yan Li, Chun-peng Zhang, Yun Zhou… in BMC Cancer (2011)