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Article
Open AccessUncovering the characteristics of the gut microbiota in patients with ischemic stroke and hemorrhagic stroke
This study aimed to explore the gut microbiota characteristics of ischemic and hemorrhagic stroke patients. A case–control study was conducted, and high-throughput sequencing of the V4–V5 region of 16S rRNA wa...
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Article
Open AccessSafety, immunogenicity and protective effect of sequential vaccination with inactivated and recombinant protein COVID-19 vaccine in the elderly: a prospective longitudinal study
The safety and efficacy of COVID-19 vaccines in the elderly, a high-risk group for severe COVID-19 infection, have not been fully understood. To clarify these issues, this prospective study followed up 157 eld...
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Article
Observation of spectral lines in the exceptional GRB 221009A
As the brightest gamma-ray burst ever observed, GRB 221009A provided a precious opportunity to explore spectral line features. In this article, we performed a comprehensive spectroscopy analysis of GRB 221009A...
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Article
Open AccessSyndromic ciliopathy: a taiwanese single-center study
Syndromic ciliopathies are a group of congenital disorders characterized by broad clinical and genetic overlap, including obesity, visual problems, skeletal anomalies, mental retardation, and renal diseases. T...
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Article
Structure of GPR101–Gs enables identification of ligands with rejuvenating potential
GPR101 is an orphan G protein-coupled receptor actively participating in energy homeostasis. Here we report the cryo-electron microscopy structure of GPR101 constitutively coupled to Gs heterotrimer, which rev...
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Article
Open AccessLactobacillus rhamnosus GG ameliorates hyperuricemia in a novel model
Hyperuricemia (HUA) is a metabolic syndrome caused by abnormal purine metabolism. Although recent studies have noted a relationship between the gut microbiota and gout, whether the microbiota could ameliorate ...
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Article
Open AccessZbtb16 increases susceptibility of atrial fibrillation in type 2 diabetic mice via Txnip-Trx2 signaling
Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia, and recent epidemiological studies suggested type 2 diabetes mellitus (T2DM) is an independent risk factor for the development of AF...
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Article
Black holes as the source of dark energy: A stringent test with high-redshift JWST AGNs
Studies have proposed that there is evidence for cosmological coupling of black holes (BHs) with an index of k ≈ 3; hence, BHs serve as the astrophysical source of dark energy. However, the data sample is limited...
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Article
Open AccessTubeimosides are pan-coronavirus and filovirus inhibitors that can block their fusion protein binding to Niemann-Pick C1
SARS-CoV-2 and filovirus enter cells via the cell surface angiotensin-converting enzyme 2 (ACE2) or the late-endosome Niemann-Pick C1 (NPC1) as a receptor. Here, we screened 974 natural compounds and identifie...
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Chapter and Conference Paper
Evaluation of the Effectiveness of Workovers for Low Amplitude and Strong Edge Water Reservoirs in South America
A low amplitude sandstone reservoir in South America was put into production in 1978, and currently has a comprehensive water cut of 93.7%. In response to the challenges of dispersed remaining oil in the main ...
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Article
Quasi-open Cu(i) sites for efficient CO separation with high O2/H2O tolerance
Carbon monoxide (CO) separation relies on chemical adsorption but suffers from the difficulty of desorption and instability of open metal sites against O2, H2O and so on. Here we demonstrate quasi-open metal site...
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Article
Open AccessCharacteristics of blood immune cell profile and their correlation with disease progression in patients infected with HIV-1
Antiretroviral therapy (ART) can reduce viral load in individuals infected with human immunodeficiency virus (HIV); however, some HIV-infected individuals still cannot achieve optimal immune recovery even afte...
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Article
Sequencing polymers to enable solid-state lithium batteries
Rational designs of solid polymer electrolytes with high ion conduction are critical in enabling the creation of advanced lithium batteries. However, known polymer electrolytes have much lower ionic conductivi...
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Article
A one-third magnetization plateau phase as evidence for the Kitaev interaction in a honeycomb-lattice antiferromagnet
The magnetization of a quantum magnet can be pinned at a fraction of its saturated value by collective effects. One example of such a plateau phase is found in spin-1/2 triangular-lattice antiferromagnets. The...
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Article
Banxia **exin Decoction Alleviated Cerebral Glucose Metabolism Disorder by Regulating Intestinal Microbiota in APP/PS1 Mice
To identify whether Banxia **exin Decoction (BXD) alleviates cerebral glucose metabolism disorder by intestinal microbiota regulation in APP/PS1 mice.
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Article
The effects of gestational diabetes mellitus on fetal growth: is it different for low-risk and medium–high-risk pregnant women?
It has been suggested that gestational diabetes mellitus (GDM) alters the growth trajectory of a fetus and increases the risk of abnormal birth weight. In spite of this, there is still a significant debate reg...
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Article
Towards reliable assessment of hydrogen oxidation electrocatalysts for anion-exchange membrane fuel cells
Recent advancement of proton exchange membrane fuel cells has led to commercial sales of fuel-cell cars but market barrier exists because this technology heavily relies on platinum catalyst. Given the permissi...
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Article
Open AccessHigh-performance hybrid nanogenerator for self-powered wireless multi-sensing microsystems
Wireless sensor network nodes are widely used in wearable devices, consumer electronics, and industrial electronics and are a crucial component of the Internet of Things (IoT). Recently, advanced power technol...
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Article
Open AccessApplication of genetic risk score for in-stent restenosis of second- and third-generation drug-eluting stents in geriatric patients
The second-and third-generation drug-eluting stents (DESs) in-stent restenosis (ISR) genetic risk score (GRS) model has been previously validated. However, the model has not been validated in geriatric patient...
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Article
Open AccessSoluble CD4 effectively prevents excessive TLR activation of resident macrophages in the onset of sepsis
T lymphopenia, occurring in the early phase of sepsis in response to systemic inflammation, is commonly associated with morbidity and mortality of septic infections. We have previously shown that a sufficient ...
