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  1. Article

    Open Access

    Identification and diagnostic potential of hsa_circ_101303 in colorectal cancer: unraveling a regulatory network

    The role of novel circular RNAs (circRNAs) in colorectal cancer (CRC) remains to be determined. This study aimed to identify a novel circRNA involved in CRC pathogenesis, assess its diagnostic value, and const...

    Ke-zhi Li, **ao-min Liao, Si-qi Li, Hao-tang Wei, Zhi-jian Liang, Liu-xin Ge in BMC Cancer (2024)

  2. Article

    Open Access

    The development of a cSMART-based integrated model for hepatocellular carcinoma diagnosis

    Hepatocellular carcinoma (HCC) generally arises from a background of liver cirrhosis (LC). Patients with cirrhosis and suspected HCC are recommended to undergo serum biomarker tests and imaging diagnostic eval...

    Tong Wu, Rong Fan, Jian Bai, Zhao Yang, Yun-Song Qian in Journal of Hematology & Oncology (2023)

  3. Article

    Open Access

    EYA2 suppresses the progression of hepatocellular carcinoma via SOCS3-mediated blockade of JAK/STAT signaling

    Somatic mutations are involved in hepatocellular carcinoma (HCC) progression, but the genetic mechanism associated to hepatocarcinogenesis remains poorly understood. We report that Eyes absent homolog 2 (EYA2)...

    Ze-Kun Liu, Can Li, Ren-Yu Zhang, Ding Wei, Yu-Kui Shang, Yu-Le Yong in Molecular Cancer (2021)

  4. Article

    Open Access

    miR-4317 suppresses non-small cell lung cancer (NSCLC) by targeting fibroblast growth factor 9 (FGF9) and cyclin D2 (CCND2)

    Non-small cell lung cancer (NSCLC) is a leading cause of death worldwide. MicroRNAs (miRNAs) have been indicated as crucial actors in cancer biology. Accumulating evidence suggests that miRNAs can be used as d...

    ** He, Si-yuan Chen, Zhao Yang, Jie Zhang in Journal of Experimental & Clinical Cancer … (2018)

  5. Article

    Open Access

    Signaling protein signature predicts clinical outcome of non-small-cell lung cancer

    Non-small-cell lung cancer (NSCLC) is characterized by abnormalities of numerous signaling proteins that play pivotal roles in cancer development and progression. Many of these proteins have been reported to b...

    Bao-Feng **, Fan Yang, **ao-Min Ying, Lin Gong, Shuo-Feng Hu, Qing Zhao in BMC Cancer (2018)

  6. Article

    Open Access

    The comparison of clinical and biological characteristics between IDH1 and IDH2 mutations in gliomas

    Mutations in isocitrate dehydrogenase 1 (IDH1) and isocitrate dehydrogenase 2 (IDH2) are frequent in low-grade gliomas and secondary glioblastomas (sGBM). Because they yield the same oncometabolite, D-2-hydroxygl...

    Hao-Yuan Wang, Kai Tang, Ting-Yu Liang in Journal of Experimental & Clinical Cancer … (2016)

  7. No Access

    Article

    Fhl1 as a downstream target of Wnt signaling to promote myogenesis of C2C12 cells

    Previous studies have shown that Wnt signaling is involved in postnatal mammalian myogenesis; however, the downstream mechanism of Wnt signaling is not fully understood. This study reports that the murine four...

    **g-Yu Lee, I-Chun Chien, Win-Yu Lin, Shao-min Wu in Molecular and Cellular Biochemistry (2012)

  8. Article

    Open Access

    Impact of residual and intrafractional errors on strategy of correction for image-guided accelerated partial breast irradiation

    The cone beam CT (CBCT) guided radiation can reduce the systematic and random setup errors as compared to the skin-mark setup. However, the residual and intrafractional (RAIF) errors are still unknown. The pur...

    Gang Cai, Wei-Gang Hu, Jia-Yi Chen, **ao-Li Yu, Zi-Qiang Pan in Radiation Oncology (2010)

  9. No Access

    Article

    The antitumor immune responses induced by nanoemulsion-encapsulated MAGE1-HSP70/SEA complex protein vaccine following peroral administration route

    Previous studies have shown that there are profuse lymphatic tissues under the intestinal mucous membrane. Moreover, vaccine administered orally can elicit both mucous membrane and system immune response simul...

    Wei Ge, Yuan Li, Zeng-Shan Li, Shan-Hong Zhang in Cancer Immunology, Immunotherapy (2009)