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Solidification behaviour and hot cracking susceptibility of a novel Ni-based superalloy
A novel Ni-based superalloy GH4151, with a γ′ volume fraction of about 55% and a service temperature capability up to 800 °C, was investigated. Due to the different cooling conditions of various regions during...
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Article
Open AccessMaternal dominance contributes to subgenome differentiation in allopolyploid fishes
Teleost fishes, which are the largest and most diverse group of living vertebrates, have a rich history of ancient and recent polyploidy. Previous studies of allotetraploid common carp and goldfish (cyprinids)...
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Open AccessA longitudinal resource for population neuroscience of school-age children and adolescents in China
During the past decade, cognitive neuroscience has been calling for population diversity to address the challenge of validity and generalizability, ushering in a new era of population neuroscience. The develop...
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Article
Multiple domestications of Asian rice
The origin of domesticated Asian rice (Oryza sativa L.) has been controversial for more than half a century. The debates have focused on two leading hypotheses: a single domestication event in China or multiple d...
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Article
Open AccessCorrection to: AT1R gene rs389566 polymorphism contributes to MACCEs in hypertension patients
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Open AccessAT1R gene rs389566 polymorphism contributes to MACCEs in hypertension patients
To investigate the possible association between AT1R gene polymorphisms and major adverse cardiovascular and cerebrovascular events (MACCEs) in hypertension patients combined with or without coronary artery di...
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Article
Open AccessThe development of a cSMART-based integrated model for hepatocellular carcinoma diagnosis
Hepatocellular carcinoma (HCC) generally arises from a background of liver cirrhosis (LC). Patients with cirrhosis and suspected HCC are recommended to undergo serum biomarker tests and imaging diagnostic eval...
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Article
Silane coupling agent treated copper foil as a current collector for silicon anode
Since the volume variation of silicon particles during cycling, the binding spots between Cu current collector and silicon anode raised to be one of the critical binding problems. In this work, an amino-modifi...
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Article
Open AccessCircSMARCC1 facilitates tumor progression by disrupting the crosstalk between prostate cancer cells and tumor-associated macrophages via miR-1322/CCL20/CCR6 signaling
Circular RNAs (circRNAs) mediate the infiltration of tumor-associated macrophages (TAMs) to facilitate carcinogenesis and development of various types of cancers. However, the role of circRNAs in regulating ma...
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Open AccessCorrection: Management of granulomatous lobular mastitis: an international multidisciplinary consensus (2021 edition)
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Article
Open AccessAssociation of annual hospital septic shock case volume and hospital mortality
The burden of sepsis remains high in China. The relationship between case volume and hospital mortality among patients with septic shock, the most severe complication of sepsis, is unknown in China.
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Cardiomyocyte peroxisome proliferator-activated receptor α is essential for energy metabolism and extracellular matrix homeostasis during pressure overload-induced cardiac remodeling
Peroxisome proliferator-activated receptor α (PPARα), a ligand-activated nuclear receptor critical for systemic lipid homeostasis, has been shown closely related to cardiac remodeling. However, the roles of ca...
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Open AccessManagement of granulomatous lobular mastitis: an international multidisciplinary consensus (2021 edition)
Granulomatous lobular mastitis (GLM) is a rare and chronic benign inflammatory disease of the breast. Difficulties exist in the management of GLM for many front-line surgeons and medical specialists who care f...
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Interdiscipline between optoelectronic materials and mechanical sensors: Recent advances of organic triboluminescent compounds and their applications in sensing
Triboluminescence, also as known as mechanoluminescence, is an attractive optical behavior that means the light emitted from specific organic and inorganic materials when they are subjected to external forces,...
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Open AccessDissecting spatial heterogeneity and the immune-evasion mechanism of CTCs by single-cell RNA-seq in hepatocellular carcinoma
Little is known about the transcriptomic plasticity and adaptive mechanisms of circulating tumor cells (CTCs) during hematogeneous dissemination. Here we interrogate the transcriptome of 113 single CTCs from 4...
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Open AccessSafety and efficacy of meplazumab in healthy volunteers and COVID-19 patients: a randomized phase 1 and an exploratory phase 2 trial
Recent evidence suggests that CD147 serves as a novel receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Blocking CD147 via anti-CD147 antibody could suppress the in vitro SAR...
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Article
A Secure Quantum Voting Scheme Based on Orthogonal Product States
As an important topic of quantum cryptography, quantum voting has attracted more and more attention in recent years. In this paper, we propose a quantum voting scheme based on a new set of orthogonal product s...
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Open AccessUnraveling tumour microenvironment heterogeneity in nasopharyngeal carcinoma identifies biologically distinct immune subtypes predicting prognosis and immunotherapy responses
Currently, there is no strong evidence of the well-established biomarkers for immune checkpoint inhibitors (ICIs) in nasopharyngeal carcinoma (NPC). Here, we aimed to reveal the heterogeneity of tumour microen...
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Open AccessCorrelations of apathy with clinical symptoms of Alzheimer’s disease and olfactory dysfunctions: a cross-sectional study
Apathy is one of the most common symptoms of Alzheimer’s disease (AD), however, correlations of apathy with demographic variables, cognitive functions, neuropsychiatric symptoms, activity of daily living and o...
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Divergence in flowering time is a major component contributing to reproductive isolation between two wild rice species (Oryza rufipogon and O. nivara)
It is of critical importance for our understanding of speciation process to determine the forms of reproductive isolation and their relative importance in species divergence. Oryza nivara and O. rufipogon are dir...
